Protein Alignment CG15706 and MFSD6L

DIOPT Version :10

• Sequence 1: NP_611099.2
• Gene: CG15706 / 36799
• FlyBaseID: FBgn0034093
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_689812.3
• Gene: MFSD6L / 162387
• HGNCID: 26656
• Length: 586
• Species: Homo sapiens
• Alignment Length: 606
• Identity: 124/606 - (20%)
• Similarity: 221/606 - (36%)
• Gaps: 171/606 - (28%)

  Fly    25 ILPQLSVIGKQIGVPPDVMGYITAALPLLYVLAKPLVGFLADYFTSLRKFIFISLI------LIM 83
            :.|.|::..:|:|:....:|.:.....|:.....|:..|||..:...|..:..||:      |:|
Human    30 VTPFLTLYLRQLGLAAPWVGTLMGTKHLIAAFWAPVCAFLAKSYRKRRALLIGSLLGSVGASLLM 94

  Fly    84 TLAFAGFYFLP----DNSHFIPLDEGSAQWNVTLL---TNPNDCNTIIQSSNAFCQTTHQAKCIQ 141
            .|       :|    :..|| |.:..|...:...|   |.|.:..:..:|:     ::|.||...
Human    95 VL-------VPPVDKNRVHF-PCNGSSGLTSTDALPGVTLPVNITSAQESA-----SSHPAKRTA 146

  Fly   142 E-----------EKEVGEFSALIV----ANESGLNLNQNLLHGNES----------YHICLT--- 178
            |           |.:...|..|.|    :.|.....:|.|||...|          :.:..|
Human   147 EVEMPGFRNPPGESDRETFRDLHVYLAPSVEGARTTSQALLHPVTSGLKDHPWEVTFEVVKTALP 211

  Fly   179 ---------QPAAIDWNSASCEVRHVNSCIYGAGKFWLF---------VCLLCIGIVGF-----N 220
                     .||.:....               ||.|.|         ..:|.:|.|.|     .
Human   212 LLPGGKGPGNPANLSGTK---------------GKAWAFDLSLEALRRTFILSLGSVAFWELLTA 261

  Fly   221 VTNSISDACCFDLLG-DEEQEKYGAQRVWGTIGF-----GATAMLAGI-----------VVNWWT 268
            ....::|...::.|. .:..::|.:..||..:|.     |.||::..:           ||:::.
Human   262 PLEQVADDSLYEFLDFVDATDRYRSLWVWRLLGMSAGVCGITALVGQLDCFLMTSGPRGVVHFYG 326

  Fly   269 TDAVKSLTPALIIMCVF--SLLDLFSVSKLKLPKLGGSESIWSDVWQLVRKPPILVFLFFAT-MA 330
            ...|.:|  ||::...|  .:...:..|..::..|           .:|...|.|:.|...| :.
Human   327 YSVVSTL--ALLVSIAFPIPICQQWEPSYKRVKAL-----------SIVGGDPHLILLASTTVLV 378

  Fly   331 GIIDSFIIYFMFWHLEQVAEATGYMHQIKLIEGLVVAAECLAGEVPFFFYSGKIIKKL---GYV- 391
            |.|.|.:..|:|||::.  ..:|     :|:.|..||.. |.||:....:...:::||   |.|
Human   379 GAIVSTVQNFLFWHMKD--HGSG-----ELVMGFSVALS-LLGEILLHPFKATLLRKLSRTGLVG 435

  Fly   392 ---HCMSMCFFFYAVRLSLIAWIPNPWYLVGVELFFQGITYALCYTCIVAYASAVAPPGTSATVQ 453
               .|::....:|:.   |.:|    |.::.::: ...|:....:..:.|....:|.|.....:.
Human   436 LGLSCLAGQLLYYSF---LWSW----WSVLPIQI-LSAISNRALWWAVGASVEDLATPRMERALS 492

  Fly   454 GLMAGMDDGLGFSIGSLIGGLMFKSLGGRESFKYFAIAAI--CTCVA---HIVIRPTSRKRQFLP 513
            .|..|...|.|.|:||.:||.:...         |::|.:  ..|||   .:.:..:.::|  ||
Human   493 ALFRGHFYGSGCSLGSFVGGFVVMR---------FSLAVLYQACCVALLLWLALLLSIQRR--LP 546

  Fly   514 RQGYVPPTEQEIKQPPAQEME 534
            |       |::||......||
Human   547 R-------ERKIKYSKLLSME 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15706	NP_611099.2	MFS_MFSD6	10..503	CDD:340893	115/573 (20%)
MFSD6L	NP_689812.3	MFS_MFSD6L	16..529	CDD:341032	112/564 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	133..160		5/31 (16%)