DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mrj and DNAJB14

DIOPT Version :9

Sequence 1:	NP_001246364.1	Gene:	mrj / 36797	FlyBaseID:	FBgn0034091	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_001026893.1	Gene:	DNAJB14 / 79982	HGNCID:	25881	Length:	379	Species:	Homo sapiens

Alignment Length:	194	Identity:	55/194 - (28%)
Similarity:	83/194 - (42%)	Gaps:	62/194 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNLDEANKRFRELSEAYEVLSDARKRRIYDA 67
            :||::|.|::.|.|.::||||||||||:|||||  :...|...|:::..||.|||:..||:.||.
Human   108 NYYEVLGVTKDAGDEDLKKAYRKLALKFHPDKN--HAPGATDAFKKIGNAYAVLSNPEKRKQYDL 170

  Fly    68 RATLHKSSNSGSSSSNSSSYTRYRNGGTGGSSSYGRDYDYDYYP--------GSGYGSGSGRRSG 124
                         :.|......::|   .|..::.|..:.|..|        |.|:.|||
Human   171 -------------TGNEEQACNHQN---NGRFNFHRGCEADITPEDLFNIFFGGGFPSGS----- 214

  Fly   125 NRYQAFTFRNIFEGTPFHKMFEKKRRIYDEYGKDGLGDRGQSRSHARHHYSTHDFDDFDILGGF 188
                ..:|.|                          |..|.|:.| :|.:|.|:.::....|||
Human   215 ----VHSFSN--------------------------GRAGYSQQH-QHRHSGHEREEERGDGGF 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mrj	NP_001246364.1	DnaJ	2..>66	CDD:223560	30/62 (48%)
mrj	NP_001246364.1	DnaJ	3..66	CDD:278647	30/62 (48%)
DNAJB14	NP_001026893.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	55..94
		DnaJ	107..>214	CDD:223560	41/123 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	219..241		8/48 (17%)
		DUF1977	271..371	CDD:370429
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810