DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mrj and dnajb6a

DIOPT Version :9

Sequence 1:	NP_001246364.1	Gene:	mrj / 36797	FlyBaseID:	FBgn0034091	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_001002353.1	Gene:	dnajb6a / 436626	ZFINID:	ZDB-GENE-040718-45	Length:	316	Species:	Danio rerio

Alignment Length:	366	Identity:	122/366 - (33%)
Similarity:	155/366 - (42%)	Gaps:	135/366 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVDYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNLDEANKRFRELSEAYEVLSDARKRRIY 65
            |.|||::|.|.::|:..::|||||||||:|||||||||.::|.|:|:||||||||||||.||.:|
Zfish     1 MADYYQVLGVQKTASPDDIKKAYRKLALRWHPDKNPDNKEDAEKKFKELSEAYEVLSDANKRSLY 65

  Fly    66 DARATLHKSSNSGSSSSNSSSYTRYRNGGTGGSSSYGRDYDYDYYPGSGYGSGSGRRSGNRYQAF 130
            |                                 .||::       |...|.|.||
Zfish    66 D---------------------------------RYGKE-------GLTPGGGGGR--------- 81

  Fly   131 TFRNIFEGTPFHKMFEKKRRIYDEYGKDGLGDRGQSRSHARHHYSTHDFDDFDILGGFQFAFRPP 195
                                                    .||:           ||..|.||.|
Zfish    82 ----------------------------------------EHHF-----------GGGGFTFRNP 95

  Fly   196 EEVFREFFGIHSPFADLFRDANGHSNGSTSGSSGSRRNGGS-SGSSRHHHHHHQHKVA------- 252
            |:|||||||...||||.|               |:...|.. .|..||:|||||..::
Zfish    96 EDVFREFFGGQDPFADFF---------------GADPFGDDFFGGRRHYHHHHQRGMSRSRTGGS 145

  Fly   253 --------SPFGAPMLNY--SMMDFFMPTSGFTSFSSMTHGNGSSGVTHISSGPG--ASVKRTST 305
                    .||||...::  ....|.....||||||:.:.|.|..|......|.|  .|.:..||
Zfish   146 FFGGFGGFPPFGAGFTSFDAGFTPFGHMGGGFTSFSTSSFGGGGGGGGGGGGGGGGMGSFRSVST 210

  Fly   306 STVFVNGKKLMTKRVVENGKETVFSYENDVLKSKTVMGSLQ 346
            ||.|:||:|:.|||:.|||:|.|...|:..|||.|:.|..|
Zfish   211 STKFINGRKITTKRIFENGQERVEVEEDGQLKSLTINGKAQ 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mrj	NP_001246364.1	DnaJ	2..>66	CDD:223560	41/63 (65%)
mrj	NP_001246364.1	DnaJ	3..66	CDD:278647	41/62 (66%)
dnajb6a	NP_001002353.1	DnaJ	3..66	CDD:278647	41/62 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	105	1.000	Domainoid score	I6575
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	143	1.000	Inparanoid score	I4437
OMA	1	1.010	-	-		QHG52292
OrthoDB	1	1.010	-	-		D593036at33208
OrthoFinder	1	1.000	-	-		FOG0000721
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102921
Panther	1	1.100	-	-	O	PTHR43948
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5097
SonicParanoid	1	1.000	-	-		X251
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.970