Protein Alignment mrj and Dnajb6

DIOPT Version :10

• Sequence 1: NP_725545.2
• Gene: mrj / 36797
• FlyBaseID: FBgn0034091
• Length: 346
• Species: Drosophila melanogaster
• Sequence 2: NP_001365764.1
• Gene: Dnajb6 / 23950
• MGIID: 1344381
• Length: 372
• Species: Mus musculus
• Alignment Length: 350
• Identity: 119/350 - (34%)
• Similarity: 148/350 - (42%)
• Gaps: 125/350 - (35%)

  Fly     1 MVDYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNLDEANKRFRELSEAYEVLSDARKRRIY 65
            |||||::|.|.|.|:..::||||||.||||||||||:|.:||.::|::::|||||||||
Mouse     1 MVDYYEVLGVQRHASPEDIKKAYRKQALKWHPDKNPENKEEAERKFKQVAEAYEVLSDA------ 59

  Fly    66 DARATLHKSSNSGSSSSNSSSYTRYRNGGTGGSSSYGRDYDYDYYPGSGYGSGSGRRSGNRYQAF 130
                                                                             
Mouse    60 ----------------------------------------------------------------- 59

  Fly   131 TFRNIFEGTPFHKMFEKKRRIYDEYGKDGL-GDRGQSRSHARHHYSTHDFDDFDILGGFQFAFRP 194
                            |||.|||:|||:|| |..|....|            ||....|.|.||.
Mouse    60 ----------------KKRDIYDKYGKEGLNGGGGGGGIH------------FDSPFEFGFTFRN 96

  Fly   195 PEEVFREFFGIHSPFA-DLFRDANGHSNGSTSGSSGSRRNGGSSGSSRHHHHHHQHKVASPFGAP 258
            |::|||||||...||: |.|.|......|:..|..|:|..|..|..|...            |.|
Mouse    97 PDDVFREFFGGRDPFSFDFFEDPFDDFFGNRRGPRGNRSRGAGSFFSTFS------------GFP 149

  Fly   259 MLNYSMMDFFMPTSGFTSFSSMTHGNGSSGVTHISS----GPG-ASVKRTSTSTVFVNGKKLMTK 318
            ........|   .:|||.|.|:.||    |:|..||    |.| .:.|..||||..|||||:.||
Mouse   150 SFGSGFPAF---DTGFTPFGSLGHG----GLTSFSSTSFGGSGMGNFKSISTSTKIVNGKKITTK 207

  Fly   319 RVVENGKETVFSYENDVLKSKTVMG 343
            |:||||:|.|...|:..|||.|:.|
Mouse   208 RIVENGQERVEVEEDGQLKSLTING 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mrj	NP_725545.2	DnaJ	3..66	CDD:395170	36/62 (58%)
Dnajb6	NP_001365764.1	Interaction with HSP70. /evidence=ECO:0000250|UniProtKB:O75190	2..147		77/255 (30%)
		PRK10767	3..>138	CDD:236757	73/233 (31%)
		Interaction with KRT18. /evidence=ECO:0000250|UniProtKB:O75190	120..243		47/131 (36%)