Protein Alignment CG44243 and LIPT1

DIOPT Version :9

• Sequence 1: NP_001188958.1
• Gene: CG44243 / 36795
• FlyBaseID: FBgn0265178
• Length: 396
• Species: Drosophila melanogaster
• Sequence 2: NP_001191759.1
• Gene: LIPT1 / 51601
• HGNCID: 29569
• Length: 373
• Species: Homo sapiens
• Alignment Length: 321
• Identity: 124/321 - (38%)
• Similarity: 192/321 - (59%)
• Gaps: 30/321 - (9%)

  Fly    51 VPDSEIKKSV-----FISQSSDVFTNLALEDWLYKNFDFSRHHVLLLWANDPCVVIGRHQNPFTE 110
            ||.:..||:|     ..|.|:||:.|||:|||::.:.:.....:|..|.|.|.|||||||||:.|
Human    19 VPAAGFKKTVKNGLILQSISNDVYQNLAVEDWIHDHMNLEGKPILFFWQNSPSVVIGRHQNPWQE 83

  Fly   111 ANVSQLVERGITLARRNSGGGAVYHDLGNLNCTFFSPRERYDRKYNLNIVTRALFREWAIKAEIN 175
            .|::.:.|.||.||||.||||.||||:||:|.|||:.:::|||..||.::.|||.   |::.:::
Human    84 CNLNLMREEGIKLARRRSGGGTVYHDMGNINLTFFTTKKKYDRMENLKLIVRALN---AVQPQLD 145

  Fly   176 ----ERDDIVVMNK-KISGTAAKLGHPNSYHHCTILASANKLHLGESLVREPANYI-SKATASVP 234
                :|.|:::..: ||||||:|:|...:|||||:|.|.:...| .||::.|...| |.||||:|
Human   146 VQATKRFDLLLDGQFKISGTASKIGRTTAYHHCTLLCSTDGTFL-SSLLKSPYQGIRSNATASIP 209

  Fly   235 SPIRNLVDVNRTVNVAQLRSAVGYEYLRTAATTLEDGGSTQTMQQRGFQLVNPT-EKWFPGIEEL 298
            |.::||::.:.|:....|.:||..||   ||....|         ....|:||| |..||||...
Human   210 SLVKNLLEKDPTLTCEVLMNAVATEY---AAYHQID---------NHIHLINPTDETLFPGINSK 262

  Fly   299 RSNYSSWDWVIGKTPKFTVQKELEVKGDEQDMKLKLSVEVEAGLMKEIGIQLPQSDQLVPV 359
            .....:|:|:.||||||::.....|..::..:::|:.::::.|.::...|:.|  |..:|:
Human   263 AKELQTWEWIYGKTPKFSINTSFHVLYEQSHLEIKVFIDIKNGRIEICNIEAP--DHWLPL 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG44243	NP_001188958.1	LplA	63..311	CDD:223173	106/254 (42%)
		lipoyltrans	60..380	CDD:161920	120/312 (38%)
LIPT1	NP_001191759.1	LplA	33..235	CDD:319742	90/205 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147270
Domainoid	1	1.000	215	1.000	Domainoid score	I2707
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H50569
Inparanoid	1	1.050	215	1.000	Inparanoid score	I3617
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54427
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003725
OrthoInspector	1	1.000	-	-		oto88755
orthoMCL	1	0.900	-	-		OOG6_101366
Panther	1	1.100	-	-	LDO	PTHR12561
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R663
SonicParanoid	1	1.000	-	-		X3085
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	13	12.930