Protein Alignment Lipt1 and LIPT1

DIOPT Version :10

• Sequence 1: NP_611097.2
• Gene: Lipt1 / 36795
• FlyBaseID: FBgn0265178
• Length: 396
• Species: Drosophila melanogaster
• Sequence 2: NP_057013.1
• Gene: LIPT1 / 51601
• HGNCID: 29569
• Length: 373
• Species: Homo sapiens
• Alignment Length: 321
• Identity: 124/321 - (38%)
• Similarity: 192/321 - (59%)
• Gaps: 30/321 - (9%)

  Fly    51 VPDSEIKKSV-----FISQSSDVFTNLALEDWLYKNFDFSRHHVLLLWANDPCVVIGRHQNPFTE 110
            ||.:..||:|     ..|.|:||:.|||:|||::.:.:.....:|..|.|.|.|||||||||:.|
Human    19 VPAAGFKKTVKNGLILQSISNDVYQNLAVEDWIHDHMNLEGKPILFFWQNSPSVVIGRHQNPWQE 83

  Fly   111 ANVSQLVERGITLARRNSGGGAVYHDLGNLNCTFFSPRERYDRKYNLNIVTRALFREWAIKAEIN 175
            .|::.:.|.||.||||.||||.||||:||:|.|||:.:::|||..||.::.|||.   |::.:::
Human    84 CNLNLMREEGIKLARRRSGGGTVYHDMGNINLTFFTTKKKYDRMENLKLIVRALN---AVQPQLD 145

  Fly   176 ----ERDDIVVMNK-KISGTAAKLGHPNSYHHCTILASANKLHLGESLVREPANYI-SKATASVP 234
                :|.|:::..: ||||||:|:|...:|||||:|.|.:...| .||::.|...| |.||||:|
Human   146 VQATKRFDLLLDGQFKISGTASKIGRTTAYHHCTLLCSTDGTFL-SSLLKSPYQGIRSNATASIP 209

  Fly   235 SPIRNLVDVNRTVNVAQLRSAVGYEYLRTAATTLEDGGSTQTMQQRGFQLVNPT-EKWFPGIEEL 298
            |.::||::.:.|:....|.:||..||   ||....|         ....|:||| |..||||...
Human   210 SLVKNLLEKDPTLTCEVLMNAVATEY---AAYHQID---------NHIHLINPTDETLFPGINSK 262

  Fly   299 RSNYSSWDWVIGKTPKFTVQKELEVKGDEQDMKLKLSVEVEAGLMKEIGIQLPQSDQLVPV 359
            .....:|:|:.||||||::.....|..::..:::|:.::::.|.::...|:.|  |..:|:
Human   263 AKELQTWEWIYGKTPKFSINTSFHVLYEQSHLEIKVFIDIKNGRIEICNIEAP--DHWLPL 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lipt1	NP_611097.2	LplA	60..260	CDD:319742	91/210 (43%)
LIPT1	NP_057013.1	LplA	33..235	CDD:319742	90/205 (44%)