DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG44243 and Lipt1

DIOPT Version :9

Sequence 1:	NP_001188958.1	Gene:	CG44243 / 36795	FlyBaseID:	FBgn0265178	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	XP_006244877.1	Gene:	Lipt1 / 316342	RGDID:	1310276	Length:	406	Species:	Rattus norvegicus

Alignment Length:	321	Identity:	121/321 - (37%)
Similarity:	187/321 - (58%)	Gaps:	30/321 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 VPDSEIKKS-----VFISQSSDVFTNLALEDWLYKNFDFSRHHVLLLWANDPCVVIGRHQNPFTE 110
            ||.:..|..     :..|.|:||:.|||:|||::.:.......:|.||.|.|.|||||||||:.|
  Rat    54 VPTAGFKSPPTHGLILQSISNDVYENLAVEDWIHDHIHLEGKPILFLWRNSPSVVIGRHQNPWQE 118

  Fly   111 ANVSQLVERGITLARRNSGGGAVYHDLGNLNCTFFSPRERYDRKYNLNIVTRALFREWAIKAEIN 175
            .|:..:.:.||.||||.||||.||||:||:|.|||:.:.:|||..||.::.|||.   |::.:::
  Rat   119 CNLHLMRQEGIKLARRKSGGGTVYHDMGNINLTFFTTKTKYDRMENLKLIVRALN---AVQPQLD 180

  Fly   176 ----ERDDIVVMNK-KISGTAAKLGHPNSYHHCTILASANKLHLGESLVREPANYI-SKATASVP 234
                ::.|:::..: ||||||:|:|...:|||||:|.|.::..|..|| :.|.:.| |.||.|:|
  Rat   181 VQPTKKFDLLLDGQFKISGTASKIGRTAAYHHCTLLCSTDRTALSSSL-KSPYHGIKSNATPSIP 244

  Fly   235 SPIRNLVDVNRTVNVAQLRSAVGYEYLRTAATTLEDGGSTQTMQQRGFQLVNPT-EKWFPGIEEL 298
            |.::||::.:.|:....|.|||..||  .|...::|          ...|:||. |..||||...
  Rat   245 STVKNLLERDSTLTCDVLMSAVAAEY--AAYHQIDD----------HVNLINPADETVFPGINSK 297

  Fly   299 RSNYSSWDWVIGKTPKFTVQKELEVKGDEQDMKLKLSVEVEAGLMKEIGIQLPQSDQLVPV 359
            .....||:||.|:||:|||.....|...:..:::::.::|:.|.::...|:.|  |..:|:
  Rat   298 IKELQSWEWVYGRTPRFTVDTMFHVPHGQACLEIQVFMDVKNGRIETCDIKAP--DHWLPL 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44243	NP_001188958.1	LplA	63..311	CDD:223173	105/254 (41%)
CG44243	NP_001188958.1	lipoyltrans	60..380	CDD:161920	118/307 (38%)
Lipt1	XP_006244877.1	LplA	67..310	CDD:223173	105/258 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340920
Domainoid	1	1.000	206	1.000	Domainoid score	I2816
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H50569
Inparanoid	1	1.050	206	1.000	Inparanoid score	I3645
OMA	1	1.010	-	-		QHG54427
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003725
OrthoInspector	1	1.000	-	-		oto95890
orthoMCL	1	0.900	-	-		OOG6_101366
Panther	1	1.100	-	-	LDO	PTHR12561
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3085
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.900