DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG44243 and lipt-1

DIOPT Version :9

Sequence 1:	NP_001188958.1	Gene:	CG44243 / 36795	FlyBaseID:	FBgn0265178	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_001379231.1	Gene:	lipt-1 / 183473	WormBaseID:	WBGene00001590	Length:	289	Species:	Caenorhabditis elegans

Alignment Length:	300	Identity:	98/300 - (32%)
Similarity:	155/300 - (51%)	Gaps:	35/300 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 SVFISQSSDVFTNLALEDWLYKNFDFSRH-HVLLLWANDPCVVIGRHQNPFTEANVSQLVERGIT 122
            :|..|.||.:|.|||.|:.:::..:.::: .:||:|:|.|.|||||||||:.|.|:....:..|.
Worm    11 TVLKSTSSCIFENLAYEEHIFRTHNVAQNGEILLMWSNRPAVVIGRHQNPWIEVNIPYANKNNIQ 75

  Fly   123 LARRNSGGGAVYHDLGNLNCTFFSPRERYDRKYNLNIVTRALFREWAIKAEINERDDIVVM--NK 185
            :.||:||||.|||||||||.:..:...::.|..||..::.||.:::::|...|:|||:.:.  .:
Worm    76 IVRRHSGGGTVYHDLGNLNISLLTTHAQHCRPKNLKFISDALNQQFSVKIVPNKRDDMELHPGER 140

  Fly   186 KISGTAAKLGHPNSYHHCTILASANKLHLGESLVREPANYI-SKATASVPSPIRNLV---DVNRT 246
            |.|||||::....:|||.|:|..|:...|.:||.....:.| |.||.||.:|....:   |.|..
Worm   141 KCSGTAARIARGQAYHHLTLLVGADLQVLSKSLKSPWRDKIESNATRSVRAPAVGFLKQDDANAN 205

  Fly   247 VNVAQLRSAVGYEYLRTAATTLEDGGSTQTMQQRGFQLVNPTE--KWFPGIEELRSNYSSWDWVI 309
            |..::|.....|..|               .::...:.||..|  |....|.::.....:|.|:.
Worm   206 VEQSKLAIVEAYRKL---------------FEESHIKTVNVAEEVKKNAEISKIFDELKAWKWIY 255

  Fly   310 GKTPKFTVQKELEVKGDEQDMKLKLSVEVEAGLMKEIGIQ 349
            ||:|||...:|           .|..:||:.||:.:...|
Worm   256 GKSPKFQYSRE-----------NKSIIEVKDGLVLDTNQQ 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44243	NP_001188958.1	LplA	63..311	CDD:223173	85/256 (33%)
CG44243	NP_001188958.1	lipoyltrans	60..380	CDD:161920	97/298 (33%)
lipt-1	NP_001379231.1	LplA	11..217	CDD:319742	77/205 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159401
Domainoid	1	1.000	148	1.000	Domainoid score	I2738
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H50569
Inparanoid	1	1.050	149	1.000	Inparanoid score	I2982
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54427
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003725
OrthoInspector	1	1.000	-	-		oto18269
orthoMCL	1	0.900	-	-		OOG6_101366
Panther	1	1.100	-	-	LDO	PTHR12561
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R663
SonicParanoid	1	1.000	-	-		X3085
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.930