DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment calypso and Uchl5

DIOPT Version :9

Sequence 1:	NP_611096.1	Gene:	calypso / 36794	FlyBaseID:	FBgn0262166	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_062508.2	Gene:	Uchl5 / 56207	MGIID:	1914848	Length:	329	Species:	Mus musculus

Alignment Length:	372	Identity:	123/372 - (33%)
Similarity:	187/372 - (50%)	Gaps:	68/372 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 MAQLADGWLELESDPGLFTLLLKDFGCHDVQVEEVYDLQ-------KPIESPYGFIFLFRWIEER 96
            |:..|..|..:|||||:||.|:|.|||...||||::.|:       ||:   :|.||||:|....
Mouse     1 MSSNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPESFEKLKPV---HGLIFLFKWQPGE 62

  Fly    97 RARRKIVETTAEIFVKDEEAISSIFFAQQVVPNSCATHALLSVLLNCNENNLQLGDTLSRLKTHT 161
            .....:|:         :..:.:||||:||:.|:|||.|::||||||...::.||:|||..|..:
Mouse    63 EPAGSVVQ---------DSRLETIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFS 118

  Fly   162 KGMSPENKGLAIGNTPELACAHNSHAMPQARRRLERTGAGVSSCRFTGEAFHFVSFVPINGQLFE 226
            :......||||:.|:..:...|||.|..|......:|.|...      :||||||:||:||:|:|
Mouse   119 QSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTPAKEE------DAFHFVSYVPVNGRLYE 177

  Fly   227 LDGLKPYPMNHGGWEDSEDWTDKFRRVMAERLGIATGEQDIRFNLMAVVPDRRIAITHKLKMLRT 291
            ||||:..|::.|.. :.:||....|.|:.:|:. ...|.:|||||||:|.||::....|:
Mouse   178 LDGLREGPIDLGAC-NQDDWITAVRPVIEKRIQ-KYSEGEIRFNLMAIVSDRKMIYEQKI----- 235

  Fly   292 NQAIVSGTLQKLLKADEQGESGNGDSQRPDTPTTLLEPSAFTARDLQSLLKNLDTEIAINEQHLA 356
                  ..||:.|..:|..::..|                      .::|..:.:|:|.|:..:.
Mouse   236 ------AELQRQLAEEEPMDTDQG----------------------STVLSAIQSEVARNQMLIE 272

  Fly   357 DENDRRHMFKVDASRRTHNYDKFICTFLSMLAHQGVLGELVSQHLLP 403
            :|..:...:|::..||.|||..||...|..||..        |.|:|
Mouse   273 EEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEH--------QQLIP 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
calypso	NP_611096.1	Peptidase_C12_UCH37_BAP1	46..274	CDD:187738	92/234 (39%)
Uchl5	NP_062508.2	Peptidase_C12	8..223	CDD:187736	92/234 (39%)
		UCH_C	264..309	CDD:375501	15/52 (29%)
		Interaction with ADRM1. /evidence=ECO:0000250	313..329
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2778
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810