| Sequence 1: | NP_477160.1 | Gene: | Lis-1 / 36791 | FlyBaseID: | FBgn0015754 | Length: | 411 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_663622.2 | Gene: | TBC1D31 / 93594 | HGNCID: | 30888 | Length: | 1066 | Species: | Homo sapiens |
| Alignment Length: | 287 | Identity: | 58/287 - (20%) |
|---|---|---|---|
| Similarity: | 117/287 - (40%) | Gaps: | 38/287 - (13%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 102 FSLTGHRASITRVIFHPIFAL---------MVSASEDATIRIWDFETGEYERSLKGHTDSVQDVA 157
Fly 158 FDAQGKLLASCSADLSIKLWD---FQQSYEC-IKTMHGHDHNVSSVAFVPAGDYVLSASRDRTIK 218
Fly 219 MWEVATGYCVKTYTGHRE----WVRMVRVHIEGSIFATCSNDQTIRVWLTNSKDC--KVELRDHE 277
Fly 278 HTVECIAWAPEAAASAINEAAGADNKKGHHQGPFLASGSRDKTIRIWDVSVGLCLLTLSGHDNWV 342
Fly 343 RGLAFHPGGKYLVSASDDKTIRVWDLR 369 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Lis-1 | NP_477160.1 | LisH | 9..40 | CDD:128913 | |
| WD40 | 100..409 | CDD:238121 | 58/287 (20%) | ||
| WD40 repeat | 111..148 | CDD:293791 | 8/45 (18%) | ||
| WD40 repeat | 154..191 | CDD:293791 | 11/40 (28%) | ||
| WD40 repeat | 196..232 | CDD:293791 | 11/35 (31%) | ||
| WD40 repeat | 239..274 | CDD:293791 | 5/36 (14%) | ||
| WD40 repeat | 280..336 | CDD:293791 | 7/55 (13%) | ||
| WD40 repeat | 342..378 | CDD:293791 | 5/28 (18%) | ||
| WD40 repeat | 384..408 | CDD:293791 | |||
| TBC1D31 | NP_663622.2 | WD 1 | 33..74 | 2/4 (50%) | |
| WD40 | 44..340 | CDD:441893 | 58/287 (20%) | ||
| WD40 repeat | 46..81 | CDD:293791 | 4/11 (36%) | ||
| WD 2 | 75..116 | 7/40 (18%) | |||
| WD40 repeat | 86..123 | CDD:293791 | 8/36 (22%) | ||
| WD 3 | 117..157 | 13/40 (33%) | |||
| WD40 repeat | 130..164 | CDD:293791 | 10/34 (29%) | ||
| WD 4 | 158..200 | 12/45 (27%) | |||
| WD40 repeat | 171..207 | CDD:293791 | 11/35 (31%) | ||
| WD 5 | 201..248 | 7/46 (15%) | |||
| WD40 repeat | 215..253 | CDD:293791 | 5/37 (14%) | ||
| WD 6 | 249..296 | 6/60 (10%) | |||
| WD40 repeat | 261..291 | CDD:293791 | 6/43 (14%) | ||
| WD 7 | 297..334 | 7/36 (19%) | |||
| WD40 repeat | 309..335 | CDD:293791 | 5/25 (20%) | ||
| RabGAP-TBC | 462..605 | CDD:480642 | |||
| DUF5401 | <684..>962 | CDD:375164 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 989..1020 | ||||
| Mediates direct interaction with PJA2. /evidence=ECO:0000269|PubMed:33934390 | 1053..1056 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||