Protein Alignment Ptp52F and Ptp99A

DIOPT Version :10

• Sequence 1: NP_611093.2
• Gene: Ptp52F / 36790
• FlyBaseID: FBgn0034085
• Length: 1433
• Species: Drosophila melanogaster
• Sequence 2: NP_651691.4
• Gene: Ptp99A / 43469
• FlyBaseID: FBgn0004369
• Length: 1397
• Species: Drosophila melanogaster
• Alignment Length: 974
• Identity: 238/974 - (24%)
• Similarity: 374/974 - (38%)
• Gaps: 264/974 - (27%)

  Fly   552 LEMKNAGSEF----IDLIAFNADYNNS----CP------TIFALFTCNATTQVRNPYAERYVEGH 602
            |....||..|    :|.:..||:...:    ||      .:..|....|:|.:.. :|.|....|
  Fly    29 LPATQAGRIFDVTNLDYVKVNAEAGKNVTIPCPGVNEHSLVDTLVWKTASTTIAQ-FANRIPLLH 92

  Fly   603 S------KQGFNASLSP--LSPYATYVCKVILYNVAGPSEPVVDADMHTTTYFPEQPESVMLEKS 659
            |      ...|....||  .|..:.|:|   |.|.....|.:||..:...   |:.||..:|...
  Fly    93 SPRIQLLSDNFGLQFSPSLASDTSEYIC---LVNDRHIPEAIVDLLVQDV---PDPPERPLLISF 151

  Fly   660 TVSSLLFNW---QPPTYTNGPIKYYQAFLMRHEASYFVPADCAIVEQDTKSETKGD-PSVNFTGL 720
            |..|:..:|   |.|  .|.|:.::  .:...|      .:..|.||..:..||.: .|...|||
  Fly   152 TSRSVNLSWAHSQHP--RNAPVTHF--IIETRE------GEDGIWEQLARIYTKTNATSYQVTGL 206

  Fly   721 APAVRYMMQVAAQNDFGMGVYTEPVIGITLPAVSDS---VTQLTVLTQGPVNNNA--VYEANVTI 780
            .|...|..::.|.|..|:.           |...:|   ||.....|..|:...|  ....:|.|
  Fly   207 TPFTVYSFRLLAVNKLGIS-----------PPSKESYYIVTLREAPTGKPIPTTAHNTSSTSVYI 260

  Fly   781 TWKVPCKSN--GDIEYFQLAF-------NGTRNNFAPVSFERRVELDTGNKQGRMSYTETEMQPQ 836
            :||.|....  |:...:::.:       |.|:..:.     |...:::...|...:||:
  Fly   261 SWKAPPPDTILGEFLGYRITYRPRDRDPNDTKEIYI-----RDNTVESHEIQNLQTYTQ------ 314

  Fly   837 FDYTVEVSVKNRD-------------------------VEQLSSSVPGSWQSP-------AGLPT 869
              |.|.|.|.|.:                         ::..::|:..||..|       ||...
  Fly   315 --YKVTVQVFNPEGLGPETTILVMTDEGVPSKPQNLTILDVSANSITMSWHPPKNQNGAIAGYHV 377

  Fly   870 I------PSDELIKQMRANVE-----ETSNPTKTAIVRLPADIMTSAS-GDIKWMALMISQKNCA 922
            .      ...|::|..|.:||     |..|.......|:.....|:.: |:   .:..|:|:...
  Fly   378 FHIHDNQTGVEIVKNSRNSVETLIHFELQNLRPYTDYRVIVKAFTTKNEGE---PSDQIAQRTDV 439

  Fly   923 GVP----------HLKYDVSSDWPK-----------VLSYQEAGADGTGDCS------------- 953
            |.|          |.:..::..|.:           ::..:.||.|...|..
  Fly   440 GGPSAPAIVNLTCHSQESITIRWRRPYEFYNTIDFYIIKTRLAGQDTHRDIRINASAKELETAMI 504

  Fly   954 LEYQTTEERWHPEPVQRQRRDGEVTSDEEIVFTIGLDKCSEVQ----KTYCN--GPLLPDT--DY 1010
            |:..||...:.   |:.......|.:.::||    |.|.||.:    :..|.  .|||..:  ||
  Fly   505 LQNLTTNSYYE---VKVAAATFSVINPKKIV----LGKFSESRIIQLQPNCEKLQPLLRQSHNDY 562

  Fly  1011 NVVVRLFTASGYSDAAVLNFKTKAAIKVTLILVSVC-SCLLLAFVLGLTVLWVRK---------- 1064
            |:.|                           ||.:. ||..:..::....||.||
  Fly   563 NLAV---------------------------LVGIIFSCFGIILIIMAFFLWSRKCFHAAYYYLD 600

  Fly  1065 ---------RLAWKRDSGQGIEDPFG---NVIAKNFAIFYTEVAKPEKLAREFKEITVVALELSY 1117
                     ::.|:.....|.|....   |..||:.|..:.:  .....:||::     |::...
  Fly   601 DPPHHPNAPQVDWEVPVKIGDEIRAAVPVNEFAKHVASLHAD--GDIGFSREYE-----AIQNEC 658

  Fly  1118 SASELGC---------HKNRYADIFPYDKNRVILDI---DAEGSDYINASFIDGHTRKKEYIATQ 1170
            .:.:|.|         .||||.:|..||.:||.|..   ..:..|||||:||||:.:...:|.||
  Fly   659 ISDDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHPTPGQKKNLDYINANFIDGYQKGHAFIGTQ 723

  Fly  1171 GPKPESVMDFWRMILQYNVRVIVQVTQFREGNTIKCHEYYP------YNVRGLTVTIKSKEVLEL 1229
            ||.|::...|||||.:..|.:||.:|...|....||..|:|      |.|  :.|.:..:||:..
  Fly   724 GPLPDTFDCFWRMIWEQRVAIIVMITNLVERGRRKCDMYWPKDGVETYGV--IQVKLIEEEVMST 786

  Fly  1230 YDRTELTVVHDKYGLKEK--------VIHYYFKKWPDHGVPEDPMHLIMFVKKVKAEKRPSYSPI 1286
            |....|.:.|.|  ||:|        |..|::..|||||.|:.|:.::.||||..|.......||
  Fly   787 YTVRTLQIKHLK--LKKKKQCNTEKLVYQYHYTNWPDHGTPDHPLPVLNFVKKSSAANPAEAGPI 849

  Fly  1287 VVHCSAGVGRTGTFIGLDLIMQRLKSESKINIFETVKKLRFQRMKMVQTQQQYTFLYACTYELV 1350
            |||||||||||||:|.||.::::::.::.:|:|..::.:|.||..:|||::||.||:....|.:
  Fly   850 VVHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEAI 913

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020	26/104 (25%)
		PTPc	1100..1345	CDD:214550	100/270 (37%)
Ptp99A	NP_651691.4	FN3	140..236	CDD:238020	28/116 (24%)
		FN3	243..337	CDD:238020	19/106 (18%)
		fn3	343..430	CDD:394996	16/89 (18%)
		FN3	442..520	CDD:238020	11/80 (14%)
		R5-PTPc-1	704..907	CDD:350397	84/206 (41%)
		R5-PTP-2	989..1182	CDD:350398