DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp52F and Ptp61F

DIOPT Version :9

Sequence 1:	NP_611093.2	Gene:	Ptp52F / 36790	FlyBaseID:	FBgn0034085	Length:	1433	Species:	Drosophila melanogaster
Sequence 2:	NP_476687.1	Gene:	Ptp61F / 38160	FlyBaseID:	FBgn0267487	Length:	548	Species:	Drosophila melanogaster

Alignment Length:	383	Identity:	107/383 - (27%)
Similarity:	168/383 - (43%)	Gaps:	78/383 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  1091 FYTEVAKPEKLAREFKEITVVALELSYSASELGCHK--NRYADIFPYDKNRVILDIDAEGS-DYI 1152
            ||.|:.  |...||.||     .:.|.|.||...::  |||.|:.|||.:|::|   ..|| |||
  Fly    33 FYKEIC--ETCDREAKE-----KQFSTSESERHTNRGLNRYRDVNPYDHSRIVL---KRGSVDYI 87

  Fly  1153 NASFIDGHTRKKEYIATQGPKPESVMDFWRMILQYNVRVIVQVTQFREGNTIKCHEYYPYNVRGL 1217
            ||:.:.....:::||.||||..::|..||.|:.:...|.::.:.:..|...||||.|:| |..|.
  Fly    88 NANLVQLERAERQYILTQGPLVDTVGHFWLMVWEQKSRAVLMLNKLMEKKQIKCHLYWP-NEMGA 151

  Fly  1218 TVTIKSKEV--------LELYDR--------TELTVVHDKYGLKEKVIHYYFKKWPDHGVPEDPM 1266
            ...:|...|        ||.|..        |:|.....:     :|:.:::..|||.|:|..|.
  Fly   152 DKALKLPHVKLTVELVRLETYQNFVRRWFKLTDLETQQSR-----EVMQFHYTTWPDFGIPSSPN 211

  Fly  1267 HLIMFVKKVKAEKRPS--YSPIVVHCSAGVGRTGTFIGLDLIMQRLKSESKINIFETVKKLRFQR 1329
            ..:.|:::|:.....|  ..|.|||||||:||:|||..:|..:..:....:.|:.:.:.:||..|
  Fly   212 AFLKFLQQVRDSGCLSRDVGPAVVHCSAGIGRSGTFCLVDCCLVLIDKYGECNVSKVLCELRSYR 276

  Fly  1330 MKMVQTQQQYTFLYACTYELVK---------------------HKIPRAALKMDGRPKSVTVPAI 1373
            |.::||..|..|.|....|.:|                     |.:......:..|.:|:.:|..
  Fly   277 MGLIQTADQLDFSYQAIIEGIKKLHDPTFLDAEEPLISNDTETHTLDELPPPLPPRVQSLNLPLA 341

  Fly  1374 PSPKKVSFPDV---------DVGSEYVSSA---------PITDLD--DGRPIVQLPSR 1411
            |:...:...::         .:|.|....|         .|.|.:  |.||:..||.|
  Fly   342 PNSGGILSLNMRAAQANGAESIGKELSKDALNNFINQHDMIHDAEVADSRPLPPLPVR 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020
		PTPc	1100..1345	CDD:214550	85/265 (32%)
		PTPc	1125..1348	CDD:238006	77/243 (32%)
Ptp61F	NP_476687.1	PTPc	34..295	CDD:214550	88/276 (32%)
Ptp61F	NP_476687.1	PTPc	62..295	CDD:238006	77/241 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45443551
Domainoid	1	1.000	133	1.000	Domainoid score	I1104
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46470
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840