Protein Alignment Ptp52F and PTP-ER

DIOPT Version :10

• Sequence 1: NP_611093.2
• Gene: Ptp52F / 36790
• FlyBaseID: FBgn0034085
• Length: 1433
• Species: Drosophila melanogaster
• Sequence 2: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Alignment Length: 1099
• Identity: 200/1099 - (18%)
• Similarity: 335/1099 - (30%)
• Gaps: 432/1099 - (39%)

  Fly   555 KNAGSEFIDLIAFNADYN--NSCPTIFALFTCNATTQVR-------NPYAERY-------VEGHS 603
            |:.|....|.:.::...|  ...||     .|::|||..       .|....:       |:|.|
  Fly   395 KSPGINTTDWLMYHRKQNPYQVQPT-----HCSSTTQSSLDSDASLTPSLGDFELKSACSVDGGS 454

  Fly   604 KQGFNASLSPLSPY---------ATYV-----CKVIL---YNVAGPSE-PVVDADMHTTTYFPEQ 650
            |.|..|||:|.|.:         :|.:     |..::   .:..||.| |.....|       :.
  Fly   455 KFGIGASLAPRSAHKHNQLLHSSSTNLKTLPECLTLVEFSSSGGGPKESPFKQKSM-------DL 512

  Fly   651 PESVMLEKSTVSSLLFNWQPPTYTNGPIKYYQAFLMRHEASYFVPADCAIVEQDTKSETKGDPSV 715
            |...:..|:|||:...|......:|            |..:..:.:.|.              ::
  Fly   513 PMPTLQAKTTVSTSSMNLLQRRGSN------------HSLTLNLHSSCG--------------NL 551

  Fly   716 NFTGLAPAVRYMMQVAAQNDFGMGVYTEPVIGITLPAVSDSVTQLTVLTQGPVNNNAVYEANVTI 780
            ..:||           :.:::.:|..........|.|.:.|..:...|.|..:..::
  Fly   552 MNSGL-----------SHSNYSLGSILNSKSSCNLDAGTASQIRADQLPQSHLLGSS-------- 597

  Fly   781 TWKVPCKSNGDIEYFQLAFNGTRNNFAPVSFERR-----VELDTGNKQGRMSYTETEMQPQFDYT 840
                               .|:|...    |.||     :.|.||:.........:..|.|....
  Fly   598 -------------------QGSRQGL----FRRRGSNHSITLKTGHTTTSCGDLNSMQQLQQQQA 639

  Fly   841 VEVSVKNRDVEQLSSSVPGSWQSPAGLPTIPSDELIKQMRANVEETSNPTKTAIVRLPADIMTSA 905
            :..:.|...:...::|......|.:.:|| |...|:::..:|...|.|         ...|:..|
  Fly   640 MLSAEKYNRLNMRTNSTGSGSGSGSNVPT-PKRGLLERRGSNQSLTLN---------MGSILGGA 694

  Fly   906 SGDIKWMALMISQK----NCAG---VPHLKYDVSSD---WPKVLSYQEAGADGTGDCSLEYQTTE 960
            :|....|..::..|    :||.   .||.:...|::   ..|..|.:..|....|..| :.|
  Fly   695 AGTEIQMTDIVQPKVTVCSCAAANQAPHQRKFFSTENLNSSKANSQKFFGQVCFGSAS-DLQ--- 755

  Fly   961 ERWHPEPVQRQRRDGEVTSDEEIVFTIGLDKCSEVQKTYCNGPLLPDT---DYNV----VVRLFT 1018
                |.|.|     ..|..|:.|..|.   .|:...:.....||.|.|   ::.:    :..|.:
  Fly   756 ----PNPQQ-----DSVREDQAIGATC---TCAGTVRNIMTRPLSPQTTSEEFKIYLASIQMLQS 808

  Fly  1019 AS---GYSDAAVLNFKTKAAIKVTLILVSVCSCLLLAFVLGLTVLWVRKRLAWKRDSGQGIEDPF 1080
            ||   ...|...||:....:.:....::....      |||              .:.:.:|.|.
  Fly   809 ASNPLNQFDLIRLNYVFDHSYQTNRNIIEQPP------VLG--------------SNARDVETPT 853

  Fly  1081 GNV--------IAKNFAIFYTEVAKP---------EKLAREF-KEITVVALELSYSASELGCH-K 1126
            ..|        :..::....:.:|:|         :::.|:. ||...:.|.........|.. |
  Fly   854 DMVPPSSEDSELLASYQTVVSRMAQPIPELKENEQKRIFRDLHKEFWDLPLNHQEKPMVFGSQTK 918

  Fly  1127 NRYADIFPYDKNRVILDID-------------------AEGSDYINASFIDGHTR-KKEYIATQG 1171
            |||..|.|.:.:||:|:.:                   :|...||||::|.|... .|.|:||||
  Fly   919 NRYKTILPNENSRVLLESESSELTSLLGEIKRTSSVTASEDLPYINANYIKGPDYVSKCYVATQG 983

  Fly  1172 PKPESVMDFWRM---------------------------ILQYNVRVIVQVTQFREGNTIKCHEY 1209
            |.|.::.:||.|                           |||...:.||.:|.|.|.|..||..|
  Fly   984 PLPNTIFEFWLMIYQNTQRYIRRCVDGGSSSSPHVDREQILQQYFQKIVMLTNFTEANRQKCAVY 1048

  Fly  1210 YPYNVRGLTVTIKSKEVLEL-------YDR-------------------------------TELT 1236
            :|..:..:.......||.:|       :||                               .::|
  Fly  1049 FPIELNEIFAVAAKCEVFQLSAAARDYFDRYLTPTFVPDTVVASSDAIDYEISGRHIGVESVKVT 1113

  Fly  1237 VVHD-----------------------KYGLKEKVI--------------------HYYFKKWPD 1258
            :..|                       .|.:::.|:                    ||::..|||
  Fly  1114 LEGDLLEALPAQGSFFLIKNVGIVRRNGYSVRKLVLLYCIRVPQSASYHLQKIYCYHYWYPDWPD 1178

  Fly  1259 HGVPED-------PMHLIMFVK-----------------KVKAEKRPSY--------SPI-VVHC 1290
            |..|.|       .:|::...|                 .:.|::...|        .|: |:||
  Fly  1179 HHSPRDINTLLDTCLHVLNLGKCESEFDIYDDTRSERNAHLAAQRLEIYQQDIFNAVQPLPVIHC 1243

  Fly  1291 SAGVGRTGTFIGL----------------DLIMQRLKSESK------------------------ 1315
            |||:||||.|..:                .::.:.|.|.|.
  Fly  1244 SAGIGRTGCFTAILNAVRQLRQSLAYSLTGMLTKSLTSSSTEEYHNPTDSDSSFTCNTIRHISHI 1308

  Fly  1316 -------------------------INIFETVKKLRFQRMKMVQTQQQYTFLY--ACTY 1347
                                     :::...|..||.||..|||..:||..::  .|.|
  Fly  1309 LDHRDAEAVKTPPSFDRLPKMPDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLY 1367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020	12/100 (12%)
		PTPc	1100..1345	CDD:214550	91/474 (19%)
PTP-ER	NP_726092.1	PTP_DSP_cys	919..1362	CDD:475123	85/442 (19%)