Protein Alignment Ptp52F and Ptprt

DIOPT Version :10

• Sequence 1: NP_611093.2
• Gene: Ptp52F / 36790
• FlyBaseID: FBgn0034085
• Length: 1433
• Species: Drosophila melanogaster
• Sequence 2: XP_063140269.1
• Gene: Ptprt / 362263
• RGDID: 1309653
• Length: 1487
• Species: Rattus norvegicus
• Alignment Length: 1478
• Identity: 313/1478 - (21%)
• Similarity: 504/1478 - (34%)
• Gaps: 430/1478 - (29%)

  Fly   185 LSACLTHTITLDTRN----NASVVVDTDATDVDTQYAEPGDLVMNVTNLASGITMITWGDPSEKN 245
            |:.||...:.|..:.    .|...........|..|:..|..|...||..:...:.||..|....
  Rat     7 LALCLLRLLLLGLQRPPLPGAGAQSAAGGCSFDEHYSNCGYSVALGTNGFTWEQINTWEKPMLDP 71

  Fly   246 CISNYVFKWQRNDCGTDQNQDTTTDVPSTE--TTNEID---YVTTTPMETTPDTPSDEVKCEWTD 305
            .:....| ...|..|....|.....:|:.:  .|:.||   |.::                  .|
  Rat    72 AVPTGSF-MMVNSSGRASGQKAHLLLPTLKENDTHCIDFHYYFSS------------------RD 117

  Fly   306 VSSDGKLREYLLTD--LQGCDLYTFQVFINENSTAKASQTFTSAEKLVSAVYEPSPTAYPTQLHW 368
            .||.|.|..|:..:  .||..::        |.:...::.:..||..:|..:   |..|  |:.:
  Rat   118 RSSPGALNVYVKVNGGPQGNPVW--------NVSGVVTEGWVKAELAISTFW---PHFY--QVIF 169

  Fly   369 TWFSPQNHPKCVANYSV-TLTGPIQ------RSENKTMNVITEETFAIFDDLDPCGIYLVEIVPN 426
            ...|.:.||..:|...| .|..|.:      |.:|..:||....||...
  Rat   170 ESVSLKGHPGYIAVDEVRVLAHPCRKAPHFLRLQNVEVNVGQNATFQCI---------------- 218

  Fly   427 QLNGSAGTKYQE------QSTVGEDQPSVIQDPVVEAEAYSMEVSWKTPEYADLCIDGYRLSGWM 485
                 ||.|:.:      |...|.| .:::...||....:|..||  ..:.:...:..||.....
  Rat   219 -----AGGKWSQHDKLWLQQWNGRD-TALMVTRVVNHRRFSATVS--VADTSQRSVSKYRCVIRS 275

  Fly   486 EDDKLVEVEALSITTQNTTVVFDKNLLACQVYIIQIIPYTKENLDGQLRQVGVETKAAIVDYTKV 550
            :....|...|..|..:..|.:....|||.....:.|.|
  Rat   276 DGGSGVSNYAELIVKEPPTPIAPPELLAVGATYLWIKP--------------------------- 313

  Fly   551 KLEMKNAGSEFID--LIAFNADYNNSCPTIFALFTCNATTQVRNPYAERYVEGHSKQGFNASLSP 613
                 ||.|...|  :|....:|..:..|                    :.|.|.....|..|..
  Rat   314 -----NANSIIGDGPIILKEVEYRTTTGT--------------------WAETHIVDSPNYKLWH 353

  Fly   614 LSPYATYVCKVILYNV----AGPSEPVVDADMHTTTYFPEQ---PESVMLEKSTVSSLLFNWQPP 671
            |.|...|..:|:|...    .||..|    .:.|.|...:.   |::|.:.......|...|:|.
  Rat   354 LDPDVEYEIRVLLTRPGEGGTGPPGP----PLTTRTKCADPVHGPQNVEIVDIRARQLTLQWEPF 414

  Fly   672 TYTNGPIKYYQAFLMRHEASYFVPADCAIVEQDTKSETKGDPSVNFT--GLAPAVRYMMQVAAQN 734
            .|         |....|..:..|.......:|..::|.....|.::|  ||.|.:...:::...|
  Rat   415 GY---------AVTRCHSYNLTVQYQYVFNQQQYEAEEVIQTSSHYTLRGLRPFMTIRLRLLLSN 470

  Fly   735 DFG------MGVYTEPVIGITLPAVSDSVTQLTVLTQGPVNNNAVYEANVTITWKVPCKSNGDIE 793
            ..|      :.|.||..:...:|        |..:..||      :|..:.|.||.|.::||.|.
  Rat   471 PEGRMESEELVVQTEEDVPGAVP--------LESIQGGP------FEEKIYIQWKPPNETNGVIT 521

  Fly   794 YFQLAFN--GTRNNFAPVSFERRVELDTGNKQGRM---SYTETEMQPQFDYTVEVSVKNRDVEQL 853
            .:::.:.  |:.:..|.:|.:|.......|:...:   .|..|    .:.:|::.|........:
  Rat   522 LYEINYKAVGSLDPSADLSSQRGKVFKLRNETHHLFVGLYPGT----TYSFTIKASTAKGFGPPV 582

  Fly   854 SSSVPGSWQSPAGLPTIPSDELIKQMRANVEETSNPTKTAIVRL--PADIMTSASGDIKWMALMI 916
            ::.:.....:|: :|...:|..:           |.|.|.|..:  ||.   |....:....|::
  Rat   583 TTRIATKISAPS-MPEYDADSPL-----------NETDTTITVMLKPAQ---SRGAPVSVYQLVV 632

  Fly   917 SQK------------NCAGVPHLKYDVSSDWPKVLSYQEA-GADGTGDCSLEYQTTEERWHPEPV 968
            .::            .|..||             :||:.| ..|     ||.|...|.:....||
  Rat   633 KEERLQKSRRAADIIECFSVP-------------VSYRNASNLD-----SLHYFAAELKPSNLPV 679

  Fly   969 QRQRRDGEVTSDEEIVFTIGLDKCSEVQKTYCNGPLLPDTDYNVVVR-LFTASGYSDAAVLNFKT 1032
            .:.             ||:|.:|   ....|.|.||.|...|::..: |..|:|.:....:...|
  Rat   680 TQP-------------FTVGDNK---TYNGYWNPPLSPLKSYSIYFQALSKANGETKINCVRLAT 728

  Fly  1033 KAAIKVTLILVSVCSCL-------------------------------LLAFV---LGLTVLWVR 1063
            ||.:....:......||                               ||.|:   ||:.:...|
  Rat   729 KAPMGSAQVTPGTPLCLLTTGASTQNSNTVEPEKQVDNTVKMAGVIAGLLMFIIILLGVMLTIKR 793

  Fly  1064 KRLAW--------------KRDSGQGIEDPFGNVIA-----------KNFAIFYT---------- 1093
            :|.|:              ::::..|.:...|.|.:           :|...|.:
  Rat   794 RRNAYSYSYYLSQRKLAKKQKETQSGAQREMGPVASTDKPTTKLSTNRNDEGFSSSSQDVNGFTD 858

  Fly  1094 ----EVAKPEKLAREFKEITVVALELSYSASEL-------------------------------- 1122
                |:::|....:.....|...:|:||...:.
  Rat   859 GSRGELSQPTLTIQTHPYRTCDPVEMSYPRDQFQPAIRVADLLQHITQMKRGQGYGFKEEYEALP 923

  Fly  1123 --------------GCHKNRYADIFPYDKNRV---ILDIDAEGSDYINASFIDGHTRKKEYIATQ 1170
                          ..:||||.:|..||.:||   :||.|.. ||||||::|||:.|.:.|||||
  Rat   924 EGQTASWDTAKEDENRNKNRYGNIISYDHSRVRLLVLDGDPH-SDYINANYIDGYHRPRHYIATQ 987

  Fly  1171 GPKPESVMDFWRMILQYNVRVIVQVTQFRE--------------------GNTIKCHEYYPYNVR 1215
            ||..|:|.||||||.|.|...||.||...|                    ...:||..|:|.:..
  Rat   988 GPMQETVKDFWRMIWQENSASIVMVTNLVEVGRHPAEHTVGTATLGRAASPGMVKCVRYWPDDTE 1052

  Fly  1216 ---GLTVTIKSKEVLELYDRTELTVVHDKYGLKEKVIHYYFKKWPDHGVPEDPMHLIMFVKKVKA 1277
               .:.||:...|.|..|.....||....|....::..::|..|||||||.....|:.||::||.
  Rat  1053 VYGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKF 1117

  Fly  1278 EKRPSYSPIVVHCSAGVGRTGTFIGLDLIMQRLKSESKINIFETVKKLRFQRMKMVQTQQQYTFL 1342
            ...|...|||||||||.||||.||.:|.::...::|..::||..|::||.||:.:|||::||.|:
  Rat  1118 LNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFV 1182

  Fly  1343 Y---------------ACTYELVKHKIPR-------AALKMDGRPKSVTVPAIPSPKKVSFPDVD 1385
            :               .|.:..:.:.|.|       :.:|.:.:..::..|.: .|:..|...:.
  Rat  1183 HDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQTLNIVTPRV-RPEDCSIGLLP 1246

  Fly  1386 VGSEYVSSAPITDLDDGRPIVQLPSRFSGLRRNSPPGENDNPTSSSNM 1433
            ...:...|..:..||...|.:           .|..||:.|..:::.|
  Rat  1247 RNHDKNRSMDVLPLDRCLPFL-----------ISVDGESSNYINAALM 1283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020	21/111 (19%)
		PTPc	1100..1345	CDD:214550	104/331 (31%)
Ptprt	XP_063140269.1	None