DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp52F and Y71G12B.31

DIOPT Version :9

Sequence 1:	NP_611093.2	Gene:	Ptp52F / 36790	FlyBaseID:	FBgn0034085	Length:	1433	Species:	Drosophila melanogaster
Sequence 2:	NP_001293450.1	Gene:	Y71G12B.31 / 3565511	WormBaseID:	WBGene00044348	Length:	423	Species:	Caenorhabditis elegans

Alignment Length:	418	Identity:	117/418 - (27%)
Similarity:	174/418 - (41%)	Gaps:	118/418 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly  1040 LILVSVCSCLLLAFVLGLTVLWV-RKRLAWKRDSGQG-----------IEDPFG---NVIAKNFA 1089
            :|:..:.:.:||...:...:|:| .|..:..|.:.:|           :|:|..   .|..|..|
Worm     6 IIIACLAASMLLMCCVTCFILYVYHKTSSRLRRASRGRTPKQVQQLPKVEEPAPPPVEVTTKEIA 70

  Fly  1090 IFYTEVA-------------------KPEKLAREFKEI----TVVALELSYSASEL--------- 1122
            :.....|                   :|:||..:..::    :.:|:|..|||...
Worm    71 VIAAAAAADGKNQINGFQKISTPAAKRPDKLRIDTNKVCPAQSAIAMETDYSADSFLASMTKEST 135

  Fly  1123 ------------------------------GCHKNRYADIFPYDKNRVILDIDAEGSDYINASFI 1157
                                          ....|||:||.|||...|.||.    .|||||||:
Worm   136 NRRRLLQDEFLVLSRTEARRLTRSTDRATRHAAANRYSDIVPYDHTLVELDT----GDYINASFV 196

  Fly  1158 DGHTRKKEYIATQGP-------KPESVMDFWRMILQYNVRVIVQVTQFREGNTIKCHEYYPYNVR 1215
            .|.:....:||||||       ..|:|.||||||:||:|..||.:.|.:|....||.||:| :..
Worm   197 QGESDATRWIATQGPIDSGECIGKETVSDFWRMIVQYDVACIVMLGQHQEDFVQKCGEYWP-SAM 260

  Fly  1216 GLTVTIKSKEVLELYDRTELTVVHDKYGLKE-----------------------KVIHYYFKKWP 1257
            |.|......:|..:.:..|.|.||.::.:..                       ||..:.:|:|.
Worm   261 GKTERYGEVDVKLVCELEEKTWVHREFDVSPTSSYSSSTKSSRKSRASRQQSHMKVSQWQYKEWK 325

  Fly  1258 DHGVPEDPMHLIMFVKKVKAEKRPSYSPIVVHCSAGVGRTGTFIGLDLIMQRLKSESKINIFETV 1322
            |.|......:.:.|:.:|:.  |...||||||||||:||||.||..|.::.|.:||..|:||..|
Worm   326 DTGGAPRIANFLEFLLQVRG--RQYTSPIVVHCSAGIGRTGVFICTDNVISRFESEGIIDIFSEV 388

  Fly  1323 KKLRFQRMKMVQTQQQYTFLYACTYELV 1350
            .:.|.||..||.|.:|    |.|.|:::
Worm   389 NRSRQQRPSMVYTVKQ----YECIYDII 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020
		PTPc	1100..1345	CDD:214550	100/317 (32%)
		PTPc	1125..1348	CDD:238006	94/252 (37%)
Y71G12B.31	NP_001293450.1	PTPc	170..414	CDD:238006	95/254 (37%)
Y71G12B.31	NP_001293450.1	Y_phosphatase	170..412	CDD:278528	95/252 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19134
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010