DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp52F and Ptp36E

DIOPT Version :9

Sequence 1:	NP_611093.2	Gene:	Ptp52F / 36790	FlyBaseID:	FBgn0034085	Length:	1433	Species:	Drosophila melanogaster
Sequence 2:	NP_001286033.1	Gene:	Ptp36E / 35091	FlyBaseID:	FBgn0267486	Length:	682	Species:	Drosophila melanogaster

Alignment Length:	467	Identity:	108/467 - (23%)
Similarity:	193/467 - (41%)	Gaps:	120/467 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly  1018 TASGYSDAAVLNFKTKAAIKV-TLILVSVCSCLLLAFVLGLTVLWVRKRLAWK-RDSGQGIED-- 1078
            :::.|.|......|::|.:.: ..|.:|:.:..||:|          :|:..: ||....:..
  Fly    24 SSARYDDVEKQQRKSRAIVSIPNTIKLSMLNSGLLSF----------ERIKLEARDENNSLSKTI 78

  Fly  1079 PFGNVIAKNFAIFYTEVAKPEKLAREFKEITVVALELSYSASELGC---------HKNRYADIFP 1134
            |.|.:..::|       .|...|.|:|..:..:..:.:.......|         .||:.....|
  Fly    79 PNGPIDIRHF-------LKLCDLRRKFPVLYKLEFQTAAKVESNTCRHALKKNNLEKNQNPKCIP 136

  Fly  1135 YDKNRVILDI--DAEGSDYINASFIDGHTRKKEYIATQGPKPESVMDFWRMILQYNVRVIVQVTQ 1197
            ||.|||:|:.  ..:.|||:|||::|...:...||.||||..|:|..:|||:.|.|:..||.:|:
  Fly   137 YDYNRVVLEKVGGLQDSDYVNASYVDSLLKPNAYIVTQGPVEETVQAYWRMVWQENISAIVMLTK 201

  Fly  1198 FREGNTIKCHEYYPYNVRGLTVTIKSKEVLELYDRTELTVVHDK------------YGLKEK--- 1247
            ..:...:.||:|:|.|:          ||.|.|....:.:|.::            |.:.||
  Fly   202 TFDFAKVMCHQYWPPNM----------EVHEQYGDIFINIVREEQLANFHIRTFRLYKMNEKQEV 256

  Fly  1248 -----VIHYYFKKWPDHGVPEDPMHLIMFVKKVK-------AEKRPSYSPIVVHCSAGVGRTGTF 1300
                 ::.:::.:|..|..|.... |:.|.::|:       .::.....||:||||.|.||:|.:
  Fly   257 TDERLILQFHYTEWYSHSCPFSNA-LLEFRRRVRLVVGNIIKDEDDMRGPILVHCSDGGGRSGVY 320

  Fly  1301 IGLDLIMQRLKSESKINIFETVKKLRFQRMKMVQTQQQYTFL----------------------- 1342
            :.:|..::..:.|...|:|..:||||..|..:|:..:||.|:
  Fly   321 MSIDANLELAEEEECFNVFGYLKKLRQSRKGLVENVEQYKFIYDTLEEHIICGKTWFPVSELSDR 385

  Fly  1343 ---------------YACTYELVKHKIPRAAL-------KMDGRPKSVTVPAIP----SPKKVSF 1381
                           |...|:.:..:.||..:       :.|.|.|:..|..:|    .|...||
  Fly   386 LKAKARRNSGTKMNEYQAEYDQICKQTPRFTIGDCAGGHRADNREKNRDVLCVPPDNFRPYLTSF 450

  Fly  1382 PDVDVGSEYVSS 1393
            .. :..::|::|
  Fly   451 QG-NAFTDYINS 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020
		PTPc	1100..1345	CDD:214550	79/320 (25%)
		PTPc	1125..1348	CDD:238006	75/289 (26%)
Ptp36E	NP_001286033.1	Y_phosphatase	125..368	CDD:395053	74/253 (29%)
Ptp36E	NP_001286033.1	Y_phosphatase	428..671	CDD:395053	9/35 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45443576
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19134
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940