Protein Alignment Ptp52F and ptpn11a

DIOPT Version :10

• Sequence 1: NP_611093.2
• Gene: Ptp52F / 36790
• FlyBaseID: FBgn0034085
• Length: 1433
• Species: Drosophila melanogaster
• Sequence 2: NP_956140.1
• Gene: ptpn11a / 333979
• ZFINID: ZDB-GENE-030131-5911
• Length: 594
• Species: Danio rerio
• Alignment Length: 570
• Identity: 153/570 - (26%)
• Similarity: 237/570 - (41%)
• Gaps: 184/570 - (32%)

  Fly   916 ISQKNCAGVPHLKYDV------SSDW----------PKVLSYQEAGADGTGDCSLEYQTTEERWH 964
            :.:|| ..|..|||.:      |..|          .|:|:  |.|.:|:      :...|.:.|
Zfish    88 LKEKN-GDVIELKYPLNCADPTSERWFHGHLSGREAEKLLT--EKGKNGS------FLVRESQSH 143

  Fly   965 PEPVQRQRRDGEVTSD----------------EEIVFTIG----LDKCSEVQKTYCNGPLLPDTD 1009
            |.......|.|:..:|                .::.:.:|    .|..:::.:.|...|::.
Zfish   144 PGDFVLSVRTGDDKTDTSEGKPKVTHVMIRCQHDLKYDVGGGEKFDSLTDLVEHYKKNPMVE--- 205

  Fly  1010 YNVVVRLFTASGYSDAAVLNFKTKAAIKVTLILVSVCSCLLLAFVLGLTVLWVRKRLAWKRDSGQ 1074
                                                        .|| |||.:::.|
Zfish   206 --------------------------------------------TLG-TVLQLKQPL-------- 217

  Fly  1075 GIEDPFGNVIAKNFAIFYTEVAKPEKLA-----------REFKEITVVALELSYSASE----LGC 1124
                   |....|.|...:.|.:..|||           .||:.:.....:|.||..|    ...
Zfish   218 -------NTTRINAAEIESRVRELSKLAEATDKVKQGFWEEFETLQQQECKLLYSRKEGQRPENK 275

  Fly  1125 HKNRYADIFPYDKNRVIL---DIDAEGSDYINASFI--DGHTR------KKEYIATQGPKPESVM 1178
            :||||.:|.|:|..||:|   |::.:|||||||:.|  |...:      |:.||||||....::.
Zfish   276 NKNRYKNILPFDHTRVVLTDGDVNEQGSDYINANLIMPDNEAKSNNSKLKRSYIATQGCLQNTIS 340

  Fly  1179 DFWRMILQYNVRVIVQVTQFREGNTIKCHEYYPYNVRGLTV--TIKSKEVLELYDRTELTVVHDK 1241
            |||||:.|.|.||||..|:..|....||.:|:| :|..|..  .::.:.|.|       |:.||
Zfish   341 DFWRMVFQENSRVIVMTTKEVERGKSKCVKYWP-DVSALKEYGAMRVRNVKE-------TMAHD- 396

  Fly  1242 YGLKE-------------KVIHYYFKKWPDHGVPEDPMHLIMFVKKVKAEKR--PSYSPIVVHCS 1291
            |.|:|             .|..|:|:.|||||||.||..::.|:::||.::.  ....|||||||
Zfish   397 YILRELKLSKVGQGNTERTVWQYHFRAWPDHGVPGDPGGVLDFLEEVKLKQEGITGAGPIVVHCS 461

  Fly  1292 AGVGRTGTFIGLDLIMQRLKS---ESKINIFETVKKLRFQRMKMVQTQQQYTFLYACTYELVKHK 1353
            ||:|||||||.:|:::..::.   :..|::.:|::.:|.||..||||:.||.|:|..    |:|.
Zfish   462 AGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMA----VQHY 522

  Fly  1354 IPRAALKMDGRPKSVTVPAIPSPKKVSFPDVDVGSEYVS-SAPITDLDDG 1402
            |.....:::...||          |:.      |.||.: ...::||..|
Zfish   523 IETLQRRIEEEQKS----------KIK------GREYTNIKYSLSDLSGG 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020
		PTPc	1100..1345	CDD:214550	108/290 (37%)
ptpn11a	NP_956140.1	SH2_N-SH2_SHP_like	5..103	CDD:198203	6/15 (40%)
		SH2_C-SH2_SHP_like	111..219	CDD:198185	22/178 (12%)
		PTPc-N11	273..525	CDD:350453	102/264 (39%)