Protein Alignment Ptp52F and ptprna

DIOPT Version :10

• Sequence 1: NP_611093.2
• Gene: Ptp52F / 36790
• FlyBaseID: FBgn0034085
• Length: 1433
• Species: Drosophila melanogaster
• Sequence 2: NP_001124060.2
• Gene: ptprna / 324790
• ZFINID: ZDB-GENE-030131-3511
• Length: 903
• Species: Danio rerio
• Alignment Length: 1086
• Identity: 235/1086 - (21%)
• Similarity: 371/1086 - (34%)
• Gaps: 311/1086 - (28%)

  Fly   312 LREYLLTDLQGCDLYTFQVFINENSTAKASQTFTSAEKLVSAVYEPSPTAYPTQLHWTWFSPQNH 376
            |:|.:|......|..|.|:...|.|....::|    :|..:|  :|.|.|...    .:.||.:.
Zfish    73 LKELMLQGFSWQDEITQQIIAKELSRIPHTRT----QKSQNA--QPPPPAAKK----VYSSPNSE 127

  Fly   377 PKCVANY-SVTLTGPIQRSENKTMNVITEETFAIFDDLDPCGIYLVEIVPNQLNGSAGTKYQEQS 440
            |....:| ...:..|.|.|..:...|          .:||.. ||.|.:.:.|:..|...||..|
Zfish   128 PGPAQSYVDYMVLDPHQSSPLRMQTV----------PVDPYS-YLQEGMTHSLHPHASMGYQRPS 181

  Fly   441 TVGEDQP-----SVIQDPVVEAEAYSMEVSWK---------TPEYADLCIDGYRLSGWMEDDKLV 491
            :....|.     .::|| .|.....|.:.|::         .|.|.||            |..|.
Zfish   182 SRSGSQQRERDRQLLQD-AVSLYLSSAQPSFRHRGAAALPAAPYYEDL------------DFPLE 233

  Fly   492 EVEALSITTQNTTVVFDKNLLACQVY--IIQIIPYTKENLDGQLRQVGVETKAAIVDYTKVKLEM 554
            ..|..::..|.|      |....|.|  :..:...|...|...|:..||:.:    |.:..:::.
Zfish   234 YGEDYTLHEQRT------NKKPPQDYSSVAGLDDDTLTQLGSLLKGFGVDPR----DLSPQQIKR 288

  Fly   555 KNAGSEFIDLIAFNADYNNSCPTIFALFTCNATTQVRNPYAERYVEGHSKQGFNASLSPLSPYAT 619
            .....:.:.    |.:..:..|         .|..|:    |..|.|..|...|...||.:..|.
Zfish   289 LTLVLQLLQ----NMEKTDQSP---------GTVTVK----ETIVAGSDKVTENGGKSPSTISAL 336

  Fly   620 YVCKVILYNVAGPSEPVVDADMHTTTYFPEQPESVMLEKSTVSSLLFNWQPPTYTNGPIKYYQAF 684
                        ||.|       |....|.||                  |.|.|..|:.
Zfish   337 ------------PSAP-------THQQAPTQP------------------PSTSTPAPVT----- 359

  Fly   685 LMRHEASYFVPADCAIVEQDTKSETKGDPSVNFTGLAPAVRYMMQVAAQNDFGMGVYTEPVIGIT 749
                     |||:..:..:|...:.|....:..|......|........|...:.:|.    |:.
Zfish   360 ---------VPAEPTLSAKDLDLKEKTANILKTTKDGTNTREEYGYIVTNQSHLSLYD----GVK 411

  Fly   750 LPAVSDSVTQLTVLTQGPVNNNAVYEANVTITWKVPCKSNGDIEYFQLAFNGTRNNFAPVSFERR 814
            |  :.....::.:.|...:|.:.|..|   :|:::                  |.|...:|.|
Zfish   412 L--LETLAERIHLSTSSFINISVVGSA---LTFRI------------------RQNALNLSAE-- 451

  Fly   815 VELDTGNKQ-GRMSYTETEMQPQFDYTVEVSVKNRDVEQLSSSVPGSWQSPAGLPTIPSDELIKQ 878
               |..||. ...::.|.|               ..::.:.:.| |......|||
Zfish   452 ---DVANKAVAEKNFLEGE---------------TGLKIIQTGV-GERSEGRGLP---------- 487

  Fly   879 MRANVEETSNPTKTAIVRLPADIMTSASGDIKWMALMISQKNCAGVPHLKYDVSSDWPKVLSYQE 943
            ....:.|.|......:|.:      :..|.:..:||.:     |.:.|....::|.  |:....|
Zfish   488 QATRIGEGSRGVVLTMVAM------ACVGTVLLVALAV-----ACLRHHARQLASG--KLGLGPE 539

  Fly   944 AGADGTGD----CSLEYQTTEERWHPEPVQRQRRDGEVTSDEEIVFTIGLDKCSEVQKTYCNGPL 1004
            |||:...|    |............|||..|:..|   ||           :.|.|...:.:||
Zfish   540 AGAETHFDYQELCRQHMAAKSSFTRPEPGGRRGTD---TS-----------RVSSVSSQFSDGP- 589

  Fly  1005 LPDTDYNVVVRLFTASGYSDAAVLNFKTKAAIKVTLILVSVCSCLLLAFVLGLTVLWVRKRLAWK 1069
                       ..:.|.:|...                                        :|.
Zfish   590 -----------QHSPSSHSSTP----------------------------------------SWS 603

  Fly  1070 RDSGQGIED-PFGNVIAKNFAIFYTEVAKPEKLAREFKEITVVALE---LSYSASELGCHKNRYA 1130
            .:..|...| ..|::|   .|.....:...::|.:|::.:.....|   :|.:..|....||||.
Zfish   604 EEPAQSNMDISTGHMI---LAYMEDHLKNKDRLQKEWEALCSYQAEPSSVSVAQCESNMEKNRYP 665

  Fly  1131 DIFPYDKNRVIL--DIDAEGSDYINAS-FIDGHTRKKEYIATQGPKPESVMDFWRMILQYNVRVI 1192
            |..|||.:||.|  :::....|||||| .||...|...|||||||.|.:|.|||:|:.:....||
Zfish   666 DFVPYDHSRVKLKAEVNPSKGDYINASTIIDHDPRLPAYIATQGPLPHTVADFWQMVWENGCTVI 730

  Fly  1193 VQVTQFREGNTIKCHEYYPYNVRGLTVTIKSKEVLELYDRTELTVVHDKYGLKEKVIHYYFKK-- 1255
            |.:|...|....:|..|:|            .|...||:..|:.:|.:....|:.::..::.|
Zfish   731 VMMTALVEDGEKQCERYWP------------DEGSSLYNIYEVNLVSEHIWCKDFLVRSFYLKNV 783

  Fly  1256 ---------------WPDHGVPEDPMHLIMFVKKVKAEKRPSYSPIVVHCSAGVGRTGTFIGLDL 1305
                           ||.:|:|.....|:.|.:||....|....||:||||.|.|||||:|.:|:
Zfish   784 QTQETRTLTQFHLLSWPANGIPSSTRPLLDFRRKVNKCYRGRSCPIIVHCSNGTGRTGTYILIDM 848

  Fly  1306 IMQRL-KSESKINIFETVKKLRFQRMKMVQTQQQYTFLYACTYELV 1350
            ::.|: |...:|:|..|::.:|.||..||:|:.|:.|......|.|
Zfish   849 VLNRMAKGVKEIDIAATLEHIRDQRPSMVRTKDQFEFALTAVAEEV 894

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020	17/100 (17%)
		PTPc	1100..1345	CDD:214550	89/268 (33%)
ptprna	NP_001124060.2	RESP18	60..>105	CDD:464394	9/35 (26%)
		Receptor_IA-2	392..480	CDD:463293	20/135 (15%)
		PTP_DSP_cys	617..897	CDD:475123	93/293 (32%)