Protein Alignment Ptp52F and Ptp10D

DIOPT Version :9

• Sequence 1: NP_611093.2
• Gene: Ptp52F / 36790
• FlyBaseID: FBgn0034085
• Length: 1433
• Species: Drosophila melanogaster
• Sequence 2: NP_996413.2
• Gene: Ptp10D / 32115
• FlyBaseID: FBgn0004370
• Length: 1990
• Species: Drosophila melanogaster
• Alignment Length: 1763
• Identity: 372/1763 - (21%)
• Similarity: 626/1763 - (35%)
• Gaps: 596/1763 - (33%)

  Fly    57 LGFSISNE------ADYSID-----------KVICRNGSGSETEANAAHVCENLNPCTFYTSV-- 102
            |..||.|.      |.|.:|           ..|.....|.|.:.:.|......|...:||:.
  Fly    45 LAISIPNNPGLDDGASYRLDYSPPFGYPEPNTTIASREIGDEIQFSRALPGTKYNFWLYYTNFTH 109

  Fly   103 ---VSFRSNVSGKP-PPSDQTIYAYTEYKQPKTTV------TSVVATANTIKVTWQTNDRACVES 157
               :::...::..| |||:.::    :.:..|..:      |....||..|||
  Fly   110 HDWLTWTVTITTAPDPPSNLSV----QVRSGKNAIILWSPPTQGSYTAFKIKV------------ 158

  Fly   158 FGITAKATDYTKSFQLLNDKSSQTFV-NLSACLTHTITLDTRNNASVVVDTDATDVDTQYAEPGD 221
            .|::..::.|.::|| :||.:.|..| .|:...|:.:...|..:....|...:.:..|:...||.
  Fly   159 LGLSEASSSYNRTFQ-VNDNTFQHSVKELTPGATYQVQAYTIYDGKESVAYTSRNFTTKPNTPGK 222

  Fly   222 LVM---NVTNLASGITMITWGDPSEKNCISNYVFKWQ---RNDCGTDQNQDTTTDVPS------- 273
            .::   |.|.|     ::.|..|......::|....:   .||......::.....|:
  Fly   223 FIVWFRNETTL-----LVLWQPPYPAGIYTHYKVSIEPPDANDSVLYVEKEGEPPGPAQAAFKGL 282

  Fly   274 -----------TETTNEIDYVTTTPMETTPDTPSDEVKCEWTDVSSDGKLREYLLTD-------- 319
                       |.:.:||...||....|.|..|        .:|:.|   |:::.::
  Fly   283 VPGRAYNISVQTMSEDEISLPTTAQYRTVPLRP--------LNVTFD---RDFITSNSFRVLWEA 336

  Fly   320 ---LQGCDLYTFQV-----------------FINENSTAKASQTFTSAEKLVSAVYEPSPTAYPT 364
               :...|.|...|                 |.:....|:..:||....|.||.    ..|::|
  Fly   337 PKGISEFDKYQVSVATTRRQSTVPRSNEPVAFFDFRDIAEPGKTFNVIVKTVSG----KVTSWP- 396

  Fly   365 QLHWTWFSPQNHPKCVANYSVTLTGPIQRSENKTMNVITEETFAIFDDLDPCGI---YLVEIVPN 426
                            |...|||. |:.....:::|.....|..|..:.||...   |  .||.:
  Fly   397 ----------------ATGDVTLR-PLPVRNLRSINDDKTNTMIITWEADPASTQDEY--RIVYH 442

  Fly   427 QLNGSAGTKYQEQSTVGEDQPSVIQDPVVEAEAYSMEVSW------------------KTPEYAD 473
            :|....|    :.||:..|:.....:.::....||:.|..                  .:|...|
  Fly   443 ELETFNG----DTSTLTTDRTRFTLESLLPGRNYSLSVQAVSKKMESNETSIFVVTRPSSPIIED 503

  Fly   474 LCIDGYRLS---GWMED--DKLVEVEAL-------SITTQNT--TVVFDKNLLACQVYIIQII-- 522
            |  ...|:.   .|..|  .|..:.|.|       .:.||.|  :.:..|||.....|.:::.
  Fly   504 L--KSIRMGLNISWKSDVNSKQEQYEVLYSRNGTSDLRTQKTKESRLVIKNLQPGAGYELKVFAV 566

  Fly   523 ----------------PYTKENL------------------DGQLRQVGV--------------- 538
                            |....|:                  .|:..:..:
  Fly   567 SHDLRSEPHAYFQAVYPNPPRNMTIETVRSNSVLVHWSPPESGEFTEYSIRYRTDSEQQWVRLPS 631

  Fly   539 --ETKAAIVDYTKVKLEMKNAGSEF---IDLIAFNA------DYNNSCPTIFALFTCNATTQV-- 590
              .|:|.|.|.||        |.::   ::.::|..      :.|.:.|.       |..:.:
  Fly   632 VRSTEADITDMTK--------GEKYTIQVNTVSFGVESPVPQEVNTTVPP-------NPVSNIIQ 681

  Fly   591 ----RN-----PYAERYVEGHSKQGF---------------NASLSPLSPYATYVCKVILYNVAG 631
                ||     |..|..||.:..:.:               |.|...||     ..:|::    |
  Fly   682 LVDSRNITLEWPKPEGRVESYILKWWPSDNPGRVQTKNVSENKSADDLS-----TVRVLI----G 737

  Fly   632 PSEPVVD--ADMHTTTY---------FPE-----QPESVML------EKSTVSSLLFNWQPPTYT 674
            ...|.|.  .|:.||:|         :|.     |.:.|:.      |:.|::   .::.|...:
  Fly   738 ELMPGVQYKFDIQTTSYGILSGITSLYPRTMPLIQSDVVVANGEKEDERDTIT---LSYTPTPQS 799

  Fly   675 NGPIKYYQAFLMRHEASYFVPADCAIVEQDTKSETKGDPSVNFTGLAPAVRYMMQVAAQNDFGMG 739
            :.....|:          |...|..|.::: |.....|..|.||||.|...|
  Fly   800 SSKFDIYR----------FSLGDAEIRDKE-KLANDTDRKVTFTGLVPGRLY------------- 840

  Fly   740 VYTEPVIGITLPAVSDSVTQLTV----------LTQGPVNNNAVYEANVTITWKVPCKSNGDIEY 794
                   .||:..||..|..|.:          :||....|  :.:..:::.|.:|   .|:...
  Fly   841 -------NITVWTVSGGVASLPIQRQDRLYPEPITQLHATN--ITDTEISLRWDLP---KGEYND 893

  Fly   795 FQLAFNGTRNNFAPVSFERRVELDTGNKQGRMSYTETEMQPQFDYTVEVSVKN-------RDVEQ 852
            |.:|:....|..|.            |...|...|.::::|..:||..|.|::       |....
  Fly   894 FDIAYLTADNLLAQ------------NMTTRNEITISDLRPHRNYTFTVVVRSGTESSVLRSSSP 946

  Fly   853 LSSS------VPG-----------------SWQSP-----------------------AGLPTIP 871
            ||:|      |||                 .|..|                       ||:....
  Fly   947 LSASFTTNEAVPGRVERFHPTDVQPSEINFEWSLPSSEANGVIRQFSIAYTNINNLTDAGMQDFE 1011

  Fly   872 SDE---LIKQMRANVEET-------------------------SNPTKTAIVRLPADIMTSAS-- 906
            |:|   :||.::..  ||                         ..|.:.|...:|.::..|:|
  Fly  1012 SEEAFGVIKNLKPG--ETYVFKIQAKTAIGFGPEREYRQTMPILAPPRPATQVVPTEVYRSSSTI 1074

  Fly   907 -------------GDIKWMALMISQ---KNCAGVPHLKYDVSSDWPKVLSYQEAGADGTGDCSLE 955
                         |.::...:::::   ||.:|:.      ...|..|.||         ...|.
  Fly  1075 QIRFRKNYFSDQNGQVRMYTIIVAEDDAKNASGLE------MPSWLDVQSY---------SVWLP 1124

  Fly   956 YQTTEERWHPEPVQRQRRDGEVTSDEEIVFTIGLDKCSEVQKTYCNGPLLPDTDYNVVVRLFT-A 1019
            ||..:. ::|         .|..|.|:  ||||.:.|...:..||||||...|.|.|.||.|| |
  Fly  1125 YQAIDP-YYP---------FENRSVED--FTIGTENCDNHKIGYCNGPLKSGTTYRVKVRAFTGA 1177

  Fly  1020 SGYSDAAVLNFKTKAAIKVTLILVSVCSCLLLAFVLGLTVLWVRKRLAWKRDSGQGIEDPFGN-- 1082
            ..::|.| .:|..:.....|.::|::...|.:..||.:|:|:.::|   :.:..:..:|...|
  Fly  1178 DKFTDTA-YSFPIQTDQDNTSLIVAITVPLTIILVLLVTLLFYKRR---RNNCRKTTKDSRANDN 1238

  Fly  1083 -------------VIAKNFAIFYTEVAKPE--KLAREFKEITVVALELSYSASELGCH--KNRYA 1130
                         ::.||||..|..::...  :.:.||:|:..|..:...:.::|.|:  |||:.
  Fly  1239 MSLPDSVIEQNRPILIKNFAEHYRLMSADSDFRFSEEFEELKHVGRDQPCTFADLPCNRPKNRFT 1303

  Fly  1131 DIFPYDKNRVILD--IDAEGSDYINASFIDGHTRKKEYIATQGPKPESVMDFWRMILQYNVRVIV 1193
            :|.|||.:|..|.  .|.||||||||:::.||...:|:|.||||...:..|||||..:.|.|.||
  Fly  1304 NILPYDHSRFKLQPVDDDEGSDYINANYVPGHNSPREFIVTQGPLHSTRDDFWRMCWESNSRAIV 1368

  Fly  1194 QVTQFREGNTIKCHEYYPYNVRGLTVTIKSKEVLELYDRTELTVVHDKY-------------GLK 1245
            .:|:..|....||.:|:|.:    ||.:       .|...::.:::|.:             |.:
  Fly  1369 MLTRCFEKGREKCDQYWPND----TVPV-------FYGDIKVQILNDSHYADWVMTEFMLCRGSE 1422

  Fly  1246 EKVI-HYYFKKWPDHGVPEDPMHLIMFVK----KVKAEKRPSYSPIVVHCSAGVGRTGTFIGLDL 1305
            :::: |::|..|||.|||..|..|:.||:    ::.||:|    ||||||||||||:||||.||.
  Fly  1423 QRILRHFHFTTWPDFGVPNPPQTLVRFVRAFRDRIGAEQR----PIVVHCSAGVGRSGTFITLDR 1483

  Fly  1306 IMQRLKSESKINIFETVKKLRFQRMKMVQTQQQYTFLYACTYELVKHKIPRAALKMDGRPKSVTV 1370
            |:|::.:...::||..|..:|.:|:.||||:|||..::.|...:::.|            :::..
  Fly  1484 ILQQINTSDYVDIFGIVYAMRKERVWMVQTEQQYICIHQCLLAVLEGK------------ENIVG 1536

  Fly  1371 PAIPSPKKVSFP----DVDVGSEYVSS------------APITDLDDGRPIV------QLPSRFS 1413
            ||........:.    .:|...:.|::            |....:||....:      .|.|.|:
  Fly  1537 PAREMHDNEGYEGQQVQLDENGDVVATIEGHLSHHDLQQAEAEAIDDENAAILHDDQQPLTSSFT 1601

  Fly  1414 GLRRNSPP 1421
            |...:.||
  Fly  1602 GHHTHMPP 1609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020	19/111 (17%)
		PTPc	1100..1345	CDD:214550	99/266 (37%)
		PTPc	1125..1348	CDD:238006	94/244 (39%)
Ptp10D	NP_996413.2	fn3	124..205	CDD:278470	21/97 (22%)
		fn3	220..304	CDD:278470	14/88 (16%)
		fn3	315..391	CDD:278470	14/90 (16%)
		FN3	405..494	CDD:238020	17/94 (18%)
		FN3	511..574	CDD:238020	12/62 (19%)
		FN3	583..671	CDD:238020	12/95 (13%)
		fn3	683..753	CDD:278470	16/78 (21%)
		fn3	787..850	CDD:278470	19/96 (20%)
		fn3	866..935	CDD:278470	18/85 (21%)
		fn3	961..1043	CDD:278470	10/83 (12%)
		PTPc	1272..1525	CDD:214550	100/267 (37%)
		PTPc	1298..1525	CDD:238006	94/241 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45443521
Domainoid	1	1.000	133	1.000	Domainoid score	I1104
eggNOG	1	0.900	-	-		E2759_KOG0791
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2866
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19134
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.840