DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp52F and Ptpmeg2

DIOPT Version :9

Sequence 1:	NP_611093.2	Gene:	Ptp52F / 36790	FlyBaseID:	FBgn0034085	Length:	1433	Species:	Drosophila melanogaster
Sequence 2:	NP_572576.1	Gene:	Ptpmeg2 / 31907	FlyBaseID:	FBgn0028341	Length:	827	Species:	Drosophila melanogaster

Alignment Length:	289	Identity:	107/289 - (37%)
Similarity:	157/289 - (54%)	Gaps:	38/289 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly  1101 LAREFKEITVVALELSYSASELGCH--KNRYADIFPYDKNRVIL---DIDAEGSDYINASFIDGH 1160
            |.:|:.:|...|.|.::..:.:..:  ||||.|:..||.:||:|   |.| |.||||||:|:||:
  Fly   533 LIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGD-EPSDYINANFVDGY 596

  Fly  1161 TRKKEYIATQGPKPESVMDFWRMILQYNVRVIVQVTQFREGNTIKCHEYY-----------PYNV 1214
            .:|..||:||||.|::..||||||.:.:..|||..|:..|...:||.:|:           .|:|
  Fly   597 KQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHV 661

  Fly  1215 RGLTVTIKSKEVLELYDRTELTVVHDKYGLKEKVIHYYFKKWPDHGVPEDPMHLIMFVKKVKAEK 1279
            |.::|     |..|.|....|.:.:.|......|.|:.|..|||:|||...|.::.|::||:.::
  Fly   662 RTISV-----ECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQ 721

  Fly  1280 -------------RPSYSPIVVHCSAGVGRTGTFIGLDLIMQRLKSESKINIFETVKKLRFQRMK 1331
                         .|...|||||||||:|||||||.||:.:.||:.....:|..||:|:|.||..
  Fly   722 AQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAY 786

  Fly  1332 MVQTQQQYTFLYACTYELVKHKIPRAALK 1360
            .:|...||.|   |...|:::...|..|:
  Fly   787 SIQMPDQYVF---CHLALIEYAYSRGMLQ 812

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020
		PTPc	1100..1345	CDD:214550	103/272 (38%)
		PTPc	1125..1348	CDD:238006	99/251 (39%)
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:238099
		Y_phosphatase	557..803	CDD:278528	100/254 (39%)
		PTPc	559..803	CDD:238006	100/252 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45443558
Domainoid	1	1.000	133	1.000	Domainoid score	I1104
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2866
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19134
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.940