Protein Alignment Ptp52F and Ptprd

DIOPT Version :10

• Sequence 1: NP_611093.2
• Gene: Ptp52F / 36790
• FlyBaseID: FBgn0034085
• Length: 1433
• Species: Drosophila melanogaster
• Sequence 2: XP_063144608.1
• Gene: Ptprd / 313278
• RGDID: 1561090
• Length: 1938
• Species: Rattus norvegicus
• Alignment Length: 1450
• Identity: 329/1450 - (22%)
• Similarity: 546/1450 - (37%)
• Gaps: 368/1450 - (25%)

  Fly   129 PKTTVTSVV--ATANTIKVTWQTNDRACVESFGITAKATDYTKSFQLLNDKSSQTF--VNLSACL 189
            ||...|.||  :||.:|.:||.:.:...|..:.|..|..:..:.::.::..::..:  ..||...
  Rat   330 PKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEEPYKEIDGIATTRYSVAGLSPYS 394

  Fly   190 THTITLDTRNN-----ASVVVDTDATDVDTQYAEPGDLVMNVTNLASGITMITWGDPSEKN-CIS 248
            .:...:...||     ||..|.|. |......:.|.|:...:  |:|...::.|.:|.|.| .|.
  Rat   395 DYEFRVVAVNNIGRGPASEPVLTQ-TSEQAPSSAPRDVQARM--LSSTTILVQWKEPEEPNGQIQ 456

  Fly   249 NY-----------VFKWQRNDCGTDQNQDTT-----------------TDVPSTETTNEIDYVTT 285
            .|           |..|.:::..  .:|.||                 |.:.....:::|..:|.
  Rat   457 GYRVYYTMDPTQHVNNWMKHNVA--DSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQ 519

  Fly   286 T-----PMETTPDTPSD-EVKCEWTD-----------VSSDGKLRE-----------YLLTDLQG 322
            |     |:....:..|: .:...||.           |..||...|           |.|..|:.
  Rat   520 TGVPGQPLNFKAEPESETSILLSWTPPRSDTIASYELVYRDGDQGEEQRITIEPGTSYRLQGLKP 584

  Fly   323 CDLYTFQVFINENSTAKASQTFTSAEKLVSA-VYEPSPTAYPTQLHWT----------WFSP--Q 374
            ..||.|::      :|::.|...::...:|| ..:..|:|.|..:..|          |..|  :
  Rat   585 NSLYYFRL------SARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVE 643

  Fly   375 NHPKCVANYSV---TLTGPIQRSENKTMNVITEETFAIFDDLDPCGIYLVEIVPNQLNGSAGTKY 436
            .....:..||:   .:.|...| .::.:.:.::.|..:.:.|:....|.:.:..:...|......
  Rat   644 KQNGIITEYSLKYAAVDGEDYR-PHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESL 707

  Fly   437 QEQSTVGEDQPSVIQDPV-VEA-EAYSMEVSWKTP----EYADLCIDGYRL-------------- 481
            .......||.||.....| ||| .|.:::|||::|    ::..  |.||::
  Rat   708 SVLIRTDEDVPSGPPRKVEVEAVNATAVKVSWRSPVPNKQHGQ--IRGYQVHYVKMENGEPKGQP 770

  Fly   482 ---------SGWMEDDKLVEVEALSITTQNTTVVFDKNLLACQVYIIQIIPYTKENLDGQLRQVG 537
                     :.|..||          .|::..::  ..|.....|.:.:..||.:....:.:...
  Rat   771 MLKDVMLADAQWEFDD----------ATEHDMII--SGLQPETSYSLTVTAYTTKGDGARSKPKL 823

  Fly   538 VETKAA-------IVDYTKVKLEMKNAGSEFIDLIAFNADYNNSCPTIFALFTCNATTQVRNPYA 595
            |.|..|       ::::|    :|..|      ||.::...:...|
  Rat   824 VSTTGAVPGRPRLVINHT----QMNTA------LIQWHPPVDTFGP------------------- 859

  Fly   596 ERYVEGHSKQGFNASLSPLSPY-----------------ATYVCKVILYNVAGPSEPVV---DAD 640
               ::|:..:.....:.||:..                 |:|:.::...|..|..|.:|   ...
  Rat   860 ---LQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYIFRLSARNKVGFGEEMVKEISVP 921

  Fly   641 MHTTTYFPEQPESVMLEKSTVSSLLFNWQPPTYT--NGPIKYYQAFLMRHEASYFVPADCAIVEQ 703
            ....|.||:...|   |.:|.:|:..:||||...  ||.|..| ..|.|......:|.:..||..
  Rat   922 EEVPTGFPQNLHS---EGTTSTSVQISWQPPVLAERNGVITKY-TLLYRDINVPLLPMEHLIVPA 982

  Fly   704 DTKSETKGDPSVNFTGLAPAVRYMMQVAAQNDFGMGVYTEPVIGITLPAVSDSVTQLTVLTQGPV 768
            ||        |:..|||.....|.::|.|....|.|.|:..|...|||     |.|........|
  Rat   983 DT--------SMTLTGLKSDTTYDVKVRAHTSKGPGPYSPSVQFRTLP-----VDQAVFAKNFHV 1034

  Fly   769 NNNAVYEANVTITWKVPCKSNGDIEYFQLAFNG----------TRN---NFAPVSFERRVELDTG 820
              .||.:.:|.::|::|...|..:.:..|..:|          |:.   |..|......|..:.|
  Rat  1035 --KAVMKTSVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRG 1097

  Fly   821 NKQGRMSYTET--------EMQPQF----DYTVEVSVKNRDVEQLSSSVPG-------------- 859
            |..|.:.:..|        ..:|.|    :....::|:..|| ..:.::.|
  Rat  1098 NSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPDV-PANENIKGYYIIIVPLKKSRGK 1161

  Fly   860 ---SWQSPAGLPTIPSDELIKQM---RANVEETSNPTKTAIVRLPADIMTS--ASGDIKWMALMI 916
               .|:||   ..:..|||:|::   |.::...........:....|::.:  ..||.|......
  Rat  1162 FIKPWESP---DEMELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFT 1223

  Fly   917 SQKNCAGVPHLKYDVSSDWPKVLSYQEAGADGTGDCSLEYQTTEERWHPEPVQRQRRDGEVTSDE 981
            :::..:|..::.:.::     |:.:.|         |..|.|:.   :.:||.....|.:..:||
  Rat  1224 NKQLQSGQEYVFFVLA-----VMDHAE---------SKMYATSP---YSDPVVSMDLDPQPITDE 1271

  Fly   982 E------------------IVFTIGLDKC--------SEVQKTYC-NGPLLPD---TDYNVVVRL 1016
            |                  ||..|.|.|.        ||.:|:.. |...:|.   ||...:.||
  Rat  1272 EEGLIWVVGPVLAVVFIICIVIAILLYKSKPDRKRAESESRKSSLPNSKEVPSHHPTDPVELRRL 1336

  Fly  1017 -FTASGYSDAAV---LNFKTKAAIKVTLILVSVCSCLLLAFVLGLTVLWVRKRLAWKRDSGQGIE 1077
             |...|..|:..   |:|.:.|:.....||                            :....||
  Rat  1337 NFQTPGSDDSGYPGNLHFSSMASHPPIPIL----------------------------ELADHIE 1373

  Fly  1078 DPFGNVIAKNFAIFYTEVAKPEKLAREFKEITVVALELSYSASELGCHKNRYADIFPYDKNRVIL 1142
            ....|...| |:..|..:...::...|            :|..|:...|||||::..||.:||:|
  Rat  1374 RLKANDNLK-FSQEYESIDPGQQFTWE------------HSNLEVNKPKNRYANVIAYDHSRVLL 1425

  Fly  1143 DI--DAEGSDYINASFIDGHTRKKEYIATQGPKPESVMDFWRMILQYNVRVIVQVTQFREGNTIK 1205
            ..  ...||||:||::|||:.::..||||||..||:..||||||.:.....:|.:|:..|.:.:|
  Rat  1426 SAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVK 1490

  Fly  1206 CHEYYP---YNVRGLTVTIKSKEVLELYDRTELTVVHDKYGLKEK--VIHYYFKKWPDHGVPEDP 1265
            |.:|:|   ....|| |.:...:.:||......|....|.|..||  |..:.|..||||||||.|
  Rat  1491 CDQYWPSRGTETHGL-VQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHP 1554

  Fly  1266 MHLIMFVKKVKAEKRPSYSPIVVHCSAGVGRTGTFIGLDLIMQRLKSESKINIFETVKKLRFQRM 1330
            ...:.|:::||....|...|:||||||||||||.||.:|.:::|:|.|..::|:..|..:|.||.
  Rat  1555 TPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRN 1619

  Fly  1331 KMVQTQQQYTFLYACTYELV 1350
            .||||:.||.|::....|.|
  Rat  1620 YMVQTEDQYIFIHDALLEAV 1639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020	31/102 (30%)
		PTPc	1100..1345	CDD:214550	99/251 (39%)
Ptprd	XP_063144608.1	None