Protein Alignment Ptp52F and Ptpn22

DIOPT Version :10

• Sequence 1: NP_611093.2
• Gene: Ptp52F / 36790
• FlyBaseID: FBgn0034085
• Length: 1433
• Species: Drosophila melanogaster
• Sequence 2: NP_001099930.1
• Gene: Ptpn22 / 295338
• RGDID: 1307992
• Length: 804
• Species: Rattus norvegicus
• Alignment Length: 332
• Identity: 98/332 - (29%)
• Similarity: 155/332 - (46%)
• Gaps: 45/332 - (13%)

  Fly  1099 EKLAREFKEITVVALELSYSASEL----------GCHKNRYADIFPYDKNRVILDI--DAEGSDY 1151
            |:.|.||  :.:......|.|.::          ...||||.||.|||.:.|.|.:  ..|.|.|
  Rat    22 EEFANEF--LKLKRQSTKYKADKIYPTTVAQRPKNIKKNRYKDILPYDHSLVELSLLTSDEDSSY 84

  Fly  1152 INASFIDGHTRKKEYIATQGPKPESVMDFWRMILQYNVRVIVQVTQFREGNTIKCHEYY------ 1210
            ||||||.|....:.|||||||...:::||||||.:|.|.|||......|....||..|:
  Rat    85 INASFIKGVYGPRAYIATQGPLSTTLLDFWRMIWEYRVLVIVMACMEFEMGKKKCERYWAEPGET 149

  Fly  1211 -----PYNVRGLTVTIKSKEVLELYDRTELTVVHDKYGLKEKVIH-YYFKKWPDHGVPEDPMHLI 1269
                 |:::...|...||.        .::..:..|:..:.:::: :::|.||||.||.....::
  Rat   150 QLQFGPFSISCETEKKKSD--------YKIRTLKAKFNSETRIVYQFHYKNWPDHDVPSSIDPIL 206

  Fly  1270 MFVKKVKAEKRPSYSPIVVHCSAGVGRTGTFIGLDLIMQRLKS---ESKINIFETVKKLRFQRMK 1331
            ..:..::..:.....|:.:|||||.||||....:|.....||.   ....::|..::::|.||..
  Rat   207 QLIWDMRCYQEDDCVPLCIHCSAGCGRTGVICAVDYTWMLLKDGIIPKNFSVFNLIQEMRTQRPS 271

  Fly  1332 MVQTQQQYTFLYACTYELVKHKIPRAALKMDGRPKSVTVP-AIPSPKKV----SFPDVDVGSEYV 1391
            :||||:||..:|:...||.|..:.  .:..:.|.:.:... :||..|..    |:| :|.....|
  Rat   272 LVQTQEQYELVYSAVLELFKRHVD--IISDNHREREIQAECSIPEQKLTIEADSYP-LDFPKNAV 333

  Fly  1392 SSAPITD 1398
            ..|.:|:
  Rat   334 RDAKMTN 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020
		PTPc	1100..1345	CDD:214550	84/271 (31%)
Ptpn22	NP_001099930.1	PTPc-N22	57..290	CDD:350450	80/240 (33%)
		Herpes_BLLF1	<539..800	CDD:282904