Protein Alignment Ptp52F and pyp2

DIOPT Version :10

• Sequence 1: NP_611093.2
• Gene: Ptp52F / 36790
• FlyBaseID: FBgn0034085
• Length: 1433
• Species: Drosophila melanogaster
• Sequence 2: NP_594899.1
• Gene: pyp2 / 2542200
• PomBaseID: SPAC19D5.01
• Length: 711
• Species: Schizosaccharomyces pombe
• Alignment Length: 870
• Identity: 212/870 - (24%)
• Similarity: 308/870 - (35%)
• Gaps: 234/870 - (26%)

  Fly   525 TKENLDGQLRQVGVETKAA--IVDYTKVKLEMKNAGSEFIDLIAFNADYNNSCPT---------- 577
            :|:..:..|:....:|::.  |:|   ::|..|.|.|...:.|      |.|.||
pombe     6 SKDEFNSTLKSFEEQTESVSWIID---LRLHSKYAVSHIKNAI------NVSLPTALLRRPSFDI 61

  Fly   578 --IFALFTCNATTQVRNPYAERYVEGHSKQGFNASLSPLSPY--ATYVCKVIL----YNVAGPSE 634
              :||...||....:....| .::...|..|.|.....:..:  ..|..|:.|    :.....|.
pombe    62 GKVFACIKCNVKVSLDEINA-IFLYDSSMAGMNRIYDLVQKFRRGGYSKKIYLLSNGFEAFASSH 125

  Fly   635 PVVDADMHTTTYFPEQPESVMLEKSTVSSLLFNWQPPTYTNGPIKYYQAFLMRHEASYFVPADCA 699
            |  ||.:.|.......|..:.:.::....:| :...|:..:.||....:|.:|...:...|....
pombe   126 P--DAIVSTEMVKESVPYKIDINENCKLDIL-HLSDPSAVSTPISPDYSFPLRVPINIPPPLCTP 187

  Fly   700 IVEQDTKSETKGDPSV-NFTGLAPAVRYMMQVAAQNDFGMGVYTEPVIGITLPAVSDSVTQLTVL 763
            .|..||.||....... .|:||.|                       ..|..|..| ||.....:
pombe   188 SVVSDTFSEFASHAEYPGFSGLTP-----------------------FSIHSPTAS-SVRSCQSI 228

  Fly   764 TQGPVN-NNAVYEANV-------TITWKVPCKSNGDIE-YFQLAFNGTRNNFAPVSFERRVELDT 819
            ...|:: .|:.::|.:       .|:....|.|..|.: .|.:..|..:...|..|........:
pombe   229 YGSPLSPPNSAFQAEMPYFPISPAISCASSCPSTPDEQKNFFIVGNAPQQTPARPSLRSVPSYPS 293

  Fly   820 GNKQGRMSYTETEMQPQFDYTVEVSVKNRDVEQLSSSVPGSWQSPAGLPTIPSDELIKQMRANVE 884
            .|.|.|.|.:.......:       ||       ||:|.....|.|.|..||...:.:...|..:
pombe   294 SNNQRRPSASRVRSFSNY-------VK-------SSNVVNPSLSQASLEIIPRKSMKRDSNAQND 344

  Fly   885 ETSNPTKTAIVRLPADIMTSASGDIKWMALMISQKNCAGVPHLKYDVSSDWPKVLSYQEAGADGT 949
            .||.             |||            ..|...|:.:.:     |.||....:.|.
pombe   345 GTST-------------MTS------------KLKPSVGLSNTR-----DAPKPGGLRRAN---- 375

  Fly   950 GDCSLEYQTTEERWHPEPVQRQRRDGEVTSDEEIVFTIGLDKCSEVQKTYCNGPLLPDTDYNVVV 1014
                            :|...:...|.:.|.|.                  .||
pombe   376 ----------------KPCFNKETKGSIFSKEN------------------KGP----------- 395

  Fly  1015 RLFTASGYSDAAVLNFKTKAAIKVTLILVSVCSCLLLAFVLGLTVLWVRKRLAWKRDSGQGIEDP 1079
              ||.:.:           .|.|     ||...|.:||.:...::.:..|||
pombe   396 --FTCNPW-----------GAKK-----VSPPPCEVLADLNTASIFYKFKRL------------- 429

  Fly  1080 FGNVIAKNFAIFYTEVAKPEKLAREFKEITVVALELSYSASELGCHKNRYADIFPYDKNRVILDI 1144
                         .|:.....||....:.....|..|.|.|.  ..||||.||.||||.||.|.:
pombe   430 -------------EEMEMTRSLAFNDSKSDWCCLASSRSTSI--SRKNRYTDIVPYDKTRVRLAV 479

  Fly  1145 DAEGSDYINASFIDGHTRKKEYIATQGPKPESVMDFWRMILQYNVR--VIVQVTQFREGNTIKCH 1207
            ....|||||||.||  ...|:|||.|.|||.:::|||.|:...:..  |||.:|...|..:.||.
pombe   480 PKGCSDYINASHID--VGNKKYIACQAPKPGTLLDFWEMVWHNSGTNGVIVMLTNLYEAGSEKCS 542

  Fly  1208 EYYPYN-------VRGLTVTIKSKEVLE-LYDRTELTVVHDKYGLKEKVIHYYFKKWPDHGVP-- 1262
            :|:|.|       ..||.::::..|..| |...|.|..:....|..:.:.|::...|.|...|
pombe   543 QYWPDNKDHALCLEGGLRISVQKYETFEDLKVNTHLFRLDKPNGPPKYIHHFWVHTWFDKTHPDI 607

  Fly  1263 EDPMHLIMFVKKVKAEKRPSYSPIVVHCSAGVGRTGTFIGLDLIMQRLKS---------ESKINI 1318
            |....:|..:.||     |:..|:.||||||||||||||.:|.|:|..|:         :||..|
pombe   608 ESITGIIRCIDKV-----PNDGPMFVHCSAGVGRTGTFIAVDQILQVPKNILPKTTNLEDSKDFI 667

  Fly  1319 FETVKKLRFQRMKMVQTQQQYTFLY 1343
            |..|..||.|||||||..:|:.|||
pombe   668 FNCVNSLRSQRMKMVQNFEQFKFLY 692

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020	17/101 (17%)
		PTPc	1100..1345	CDD:214550	104/265 (39%)
pyp2	NP_594899.1	DSP_MapKP	4..129	CDD:238723	28/134 (21%)
		PHA03247	<159..304	CDD:223021	35/168 (21%)
		PTP_fungal	486..693	CDD:350509	83/214 (39%)