DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp52F and pyp3

DIOPT Version :9

Sequence 1:	NP_611093.2	Gene:	Ptp52F / 36790	FlyBaseID:	FBgn0034085	Length:	1433	Species:	Drosophila melanogaster
Sequence 2:	NP_594934.1	Gene:	pyp3 / 2541443	PomBaseID:	SPAC11E3.09	Length:	303	Species:	Schizosaccharomyces pombe

Alignment Length:	309	Identity:	109/309 - (35%)
Similarity:	156/309 - (50%)	Gaps:	53/309 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly  1075 GIEDPFGNVIAKNFAIFYTEVAKPEKLAREFKEITVVALELSYSASELGCHKNRYADIFPYDKNR 1139
            |:..|...:..|.:.|.       |.|..|  ||.::...|. ..|:....:|||::|.||:..|
pombe    11 GVLTPLITIKEKAYMII-------EGLNEE--EIELLNTRLP-KLSKKALARNRYSNIVPYENTR 65

  Fly  1140 VILD-IDAEGSDYINASFI---DGHTRKKEYIATQGPKPESVMDFWRMILQYNVR--VIVQVTQF 1198
            |.|| :..|..||||||.:   .|    |.:||||||...|:..||:|:.|...:  :||.:|:.
pombe    66 VRLDPMWKEACDYINASIVKIPSG----KTFIATQGPTSNSIDVFWKMVWQSVPKSGIIVMLTKL 126

  Fly  1199 REGNTIKCHEYYP------YNVRGLTVTIKSKEVLELYDRTELTVVH------DKYGLKEKVIHY 1251
            ||.:.:||..|:|      .|:..|:|.:     :::|..|.|..|.      :|.|:|:|::|:
pombe   127 RERHRLKCDIYWPVELFETLNIGDLSVIL-----VKVYTLTSLNEVQVREFELNKDGVKKKILHF 186

  Fly  1252 YFKKWPDHGVPEDPMHLIMFVKKVKAEKRPSYS------PIVVHCSAGVGRTGTFIGLDLIMQRL 1310
            |:..|||.|.|    |....:...:..|..|||      ||:||||||.||||||:.|..|:.:.
pombe   187 YYNGWPDFGAP----HTFSLLSLTRYIKSLSYSPDFETAPIIVHCSAGCGRTGTFMALFEILSQT 247

  Fly  1311 ---KSESKI---NIFETVKKLRFQRMKMVQTQQQYTFLYACTYELVKHK 1353
               .|.||.   ||...|..||.|||:.||:..|..|||..:.||::.|
pombe   248 DDSTSTSKFEVDNIANIVSSLRSQRMQSVQSVDQLVFLYTVSQELLQGK 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020
		PTPc	1100..1345	CDD:214550	101/274 (37%)
		PTPc	1125..1348	CDD:238006	95/252 (38%)
pyp3	NP_594934.1	COG5599	1..303	CDD:227886	109/309 (35%)
		AbiGii_2	<18..69	CDD:293478	17/60 (28%)
		PTPc	52..291	CDD:238006	95/251 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0791
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm47137
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810