Protein Alignment Ptp52F and Ptprc

DIOPT Version :10

• Sequence 1: NP_611093.2
• Gene: Ptp52F / 36790
• FlyBaseID: FBgn0034085
• Length: 1433
• Species: Drosophila melanogaster
• Sequence 2: NP_612516.2
• Gene: Ptprc / 24699
• RGDID: 3451
• Length: 1273
• Species: Rattus norvegicus
• Alignment Length: 987
• Identity: 256/987 - (25%)
• Similarity: 356/987 - (36%)
• Gaps: 311/987 - (31%)

  Fly   587 TTQVRNPYAERYVEGHSK----QGFNASLSP-LSPYATYVCKVILYNVAGPSEPVVD-------A 639
            ||:...|.......|.|:    .||:::|.| |:|..         :...||....|       |
  Rat    49 TTEFTPPSISERGNGSSETTYLPGFSSTLMPHLTPQP---------DSQTPSARGADTQTLSSQA 104

  Fly   640 DMHTTTYFPE---QPESVMLEKSTVSSLLFNWQPPTYTNG-PIKYYQAFLMRHEASYFVPADCAI 700
            |:.|.|..|.   .|..|. |:|||        |.|:..| ||      |.|:..:   |:....
  Rat   105 DLTTLTAAPSGETDPPGVP-EESTV--------PETFPGGTPI------LARNSTA---PSPTHT 151

  Fly   701 VEQDTKSETKGDPSVNFTGLAPA-------------------------------VRYMMQVAAQN 734
            ....|...:.|   .|.|..||:                               |||:...:::|
  Rat   152 SNVSTTDISSG---ANLTTPAPSTLGFASNTTTSTEIATPQTKPSCDEKFGNVTVRYIYDDSSKN 213

  Fly   735 DFGMGV---------YTEPVIGI-TLPAVS-------------DSVTQLTVLTQGPVNNNAV--- 773
             |...:         ||:....: .||..|             |.:..|.| ..|..|.|..
  Rat   214 -FNANLEGDKKPKCEYTDCEKELKNLPECSQKNVTLSNGSCTPDKIINLDV-PPGTHNFNLTNCT 276

  Fly   774 --YEANVTI--TWKVPCKSNGDIE-------------YFQLAFNGT------------------- 802
              .|||.:|  .||:..|...||:             .|.|..:||
  Rat   277 PDIEANTSICLEWKIKNKFTCDIQKISYNFRCTPEMKTFALDKHGTLWLHNLTVRTNYTCAAEVL 341

  Fly   803 RNNFAPVSFERRVELDTGNKQGRMSYTETEMQPQFDYTVEVSVKNRDVEQLSSSVPGSWQSPAG- 866
            .||...:..:|||:.|.|.         .||.|      .|..||    ..:|:...||..||.
  Rat   342 YNNVILLKQDRRVQTDFGT---------PEMLP------HVQCKN----STNSTTLVSWAEPASK 387

  Fly   867 -------LPTIPSDEL-----------IKQMRANVEET-------------SNPTKTAIVRLPAD 900
                   ....||::.           :|.:|...|.|             :.|.|....|..|
  Rat   388 HHGYILCYKKTPSEKCENLANDVNSFEVKNLRPYTEYTVSLFAYVIGRVQRNGPAKDCNFRTKA- 451

  Fly   901 IMTSASGDIKWMALMISQKNCAGVPHLKYDVSSDWPKVLSYQEAGADGTGDCSLEYQTTEERWHP 965
               :..|.:..|....:..|...|                          .|:..|:..    .|
  Rat   452 ---ARPGKVNGMKTSRASDNSINV--------------------------TCNSPYEIN----GP 483

  Fly   966 EPVQRQRRDGEVTSDEEIVFTIGLDKCSEVQKTYCNGPLLPDTDYNVVVRLFTASGYSDAAV--- 1027
            |    .|...||.|...:|.|.....|..|...     |...|||..:|..:......|..:
  Rat   484 E----ARYILEVKSGGSLVKTFNQSTCKFVVDN-----LYYSTDYEFLVYFYNGEYLGDPEIKPQ 539

  Fly  1028 -LNFKTKAAIKVTLILVSVCSCLLLAFVLGLTVLWVRKRLAWKRDSGQGI-----------EDP- 1079
             .::.:||.|...:.|:.|.|..||  |:...:..:||:.:...|..|.:           .||
  Rat   540 STSYNSKALIIFLVFLIIVTSIALL--VVLYKIYDLRKKRSSNLDEQQELVERDEEKQLINVDPI 602

  Fly  1080 --------FGNVIAKNFAIFYTEVAKPEKLAREFKEITVVALELSYSASELGCHKNRYADIFPYD 1136
                    :...||....:|..|.   :.:.|.|.:..:.....|.:.     :||||.||.|||
  Rat   603 HSDLLLETYKRKIADEGRLFLAEF---QSIPRVFSKFPIKDARKSQNQ-----NKNRYVDILPYD 659

  Fly  1137 KNRVIL-DIDAE-GSDYINASFIDGHTRKKEYIATQGPKPESVMDFWRMILQYNVRVIVQVTQFR 1199
            .|||.| :|:.: ||.|||||:|||....::|||.|||:.|:|.|||:||.:....|||.||:..
  Rat   660 YNRVELSEINGDAGSTYINASYIDGFKEPRKYIAAQGPRDETVDDFWKMIWEQKATVIVMVTRCE 724

  Fly  1200 EGNTIKCHEYYP------YNVRGLTVTIKSKEVLELYDRTELTVVHDKYGLKEK-----VIHYYF 1253
            |||..||.||:|      ...|.:.|||...:....|...:|::.|.    |||     |.|..|
  Rat   725 EGNRNKCAEYWPCMEEGTRTFRDVVVTINDHKRCPDYIIQKLSIAHK----KEKATGREVTHIQF 785

  Fly  1254 KKWPDHGVPEDPMHLIMFVKKVKAEKRPSYSPIVVHCSAGVGRTGTFIGLDLIMQRLKSESKINI 1318
            ..||||||||||..|:...::|.|.......|||||||||||||||:||:|.:::.|::|.|:::
  Rat   786 TSWPDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLESLEAEGKVDV 850

  Fly  1319 FETVKKLRFQRMKMVQTQQQYTF--------------------LYACTYELVKHKIPRAALKMDG 1363
            :..|..||.||..|||.:.||..                    |::|...|.|...|     .|.
  Rat   851 YGYVVNLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHSCLQNLKKRDPP-----SDP 910

  Fly  1364 RPKSVTVPAIPS 1375
            .|.......:||
  Rat   911 SPLEAEYQRLPS 922

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020	28/145 (19%)
		PTPc	1100..1345	CDD:214550	111/277 (40%)
Ptprc	NP_612516.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	45..192		39/172 (23%)
		PHA03255	82..>191	CDD:165513	29/138 (21%)
		CD45	203..259	CDD:432641	11/56 (20%)
		FN3	366..431	CDD:238020	14/68 (21%)
		FN3	454..534	CDD:238020	21/118 (18%)
		Wzy_O6_O28	521..>580	CDD:468211	13/60 (22%)
		R-PTPc-C-1	676..876	CDD:350405	91/203 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	960..984
		R-PTP-C-2	986..1191	CDD:350406
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1219..1273