DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp52F and T27A3.5

DIOPT Version :9

Sequence 1:	NP_611093.2	Gene:	Ptp52F / 36790	FlyBaseID:	FBgn0034085	Length:	1433	Species:	Drosophila melanogaster
Sequence 2:	NP_491761.3	Gene:	T27A3.5 / 188965	WormBaseID:	WBGene00020841	Length:	355	Species:	Caenorhabditis elegans

Alignment Length:	320	Identity:	102/320 - (31%)
Similarity:	163/320 - (50%)	Gaps:	50/320 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly  1063 RKRLAWKRDSGQGIEDPFGNVIAKNFAIFYTEVAKPEKLAREFKEITV------VALE-LSYSAS 1120
            :||.|.||          ..|:.:  |..|.:|.:|  :.|:|.:.|:      ::.| |:....
Worm    34 KKRPAKKR----------SKVVRR--AAQYGDVNEP--ILRDFVKATIQTGVKQLSTEFLNLKME 84

  Fly  1121 ELGCH-----------KNRYADIFPYDKNRVILDIDAEG-SDYINASFIDGHTRKKEYIATQGPK 1173
            ...|:           ||||.|::..|..||:|....:. ||||:|:::..:...| :|.||||.
Worm    85 TQPCNKPKTGHEGHPEKNRYKDVYCIDDTRVVLKWPEDSPSDYIHANWVKINGANK-FICTQGPT 148

  Fly  1174 PESVMDFWRMILQYNVRVIVQVTQFREGNTIKCHEYYPYNVRG--------LTVTI--KSKEVLE 1228
            .::|.||:|:|.|.....:|.:....|....||.:|:|....|        |||.|  .:|||.:
Worm   149 EKTVDDFYRLIWQEKAPCVVMLCNIMECGKKKCEQYWPETADGQMILMDGKLTVKIAEPAKEVEQ 213

  Fly  1229 LYDRTELTVVHDKYGLKEKVIHYYFKKWPDHGVPEDPMHLIMFVKKVKAEKRPSYSPIVVHCSAG 1293
            .....::||:.|| |......|:.:|.|||.||||.||.:...:.::|     :.||||||||||
Worm   214 NILLMKITVIDDK-GTSHNFEHWQWKAWPDRGVPELPMAVFRLLIRLK-----TASPIVVHCSAG 272

  Fly  1294 VGRTGTFIGLDLIMQRLKSESKINIFETVKKLRFQRMKMVQTQQQYTFLYACTYELVKHK 1353
            :||||:.:||::.:.:..:..|:.:.:.||::|.||...|||..||.|::.....|.:::
Worm   273 IGRTGSIVGLEIALVKFCAGEKVVLKDIVKEIRNQRHGSVQTDAQYLFMHRVLLALAENR 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020
		PTPc	1100..1345	CDD:214550	91/273 (33%)
		PTPc	1125..1348	CDD:238006	85/244 (35%)
T27A3.5	NP_491761.3	PTPc	73..326	CDD:214550	88/259 (34%)
T27A3.5	NP_491761.3	PTPc	100..326	CDD:238006	85/232 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	3	2.870