DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp52F and F40G12.10

DIOPT Version :9

Sequence 1:	NP_611093.2	Gene:	Ptp52F / 36790	FlyBaseID:	FBgn0034085	Length:	1433	Species:	Drosophila melanogaster
Sequence 2:	NP_506537.1	Gene:	F40G12.10 / 179927	WormBaseID:	WBGene00009605	Length:	438	Species:	Caenorhabditis elegans

Alignment Length:	350	Identity:	72/350 - (20%)
Similarity:	133/350 - (38%)	Gaps:	71/350 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  1064 KRLAWKRDSGQGIEDP--------------FGNV--IAKNFAIFYTEVAKPE---KLAREFKEIT 1109
            |:|..|::.....:.|              .|||  :.|...::...:.|.:   .:..|||.|.
Worm    85 KKLKKKKEETSASKSPSTLTLGKAESHMDFSGNVKNVEKGVKVWIELLEKMDFRKTMEPEFKPID 149

  Fly  1110 VVALEL----------SYSASELGCHKNRYADIFPYDKNRVILDIDAEGSDYINASFIDGHTRKK 1164
            .:..:|          .:|.||         ::..||.|||....:|:...:.:...|...|.|.
Worm   150 TMKADLEKCQAFKKNIDFSQSE---------NVELYDTNRVKGGGEADFFYHGSTLTIPSVTTKS 205

  Fly  1165 EYIATQG--PKPESVMDFWRMILQYNVRVIVQVTQFREGNTIKCHEYYPYNVRGL-TVTIKSKEV 1226
            ..:|...  ..|:|:..||.|:....::.:..:....|.:.....||:|.:.:.. |:.:.:::.
Worm   206 TILAQLAIVDSPQSLESFWIMVASQKIQRLFILLGEEELDKPTLSEYFPEDFKEFKTIRVNNRKT 270

  Fly  1227 LELYDRTELTVVHDKYGLKE---------KVIHYYFKKWPDHGVPEDPMHLIMFVKKVKAEKRPS 1282
            :...:....|.::.:...|:         ::..:    |||..:|      .|...::.|.....
Worm   271 VPKTEEQANTQLYYEVVPKDCAEAPFAMIEICDF----WPDAKIP------TMGYNRIAATAASV 325

  Fly  1283 YSPIVVHCSA--------GVGRTGTFIGLDLIMQRLKSESKINIFETVKKLRFQRMKMVQTQQQY 1339
            :.. .:.|.|        |.||.|:|....|.:::|::....||.|....:|.||...::|..||
Worm   326 FES-DIDCDASCAIVSNYGAGRAGSFFVAVLAIEKLQAGEAPNIKEIALSVRSQRPAAIETLSQY 389

  Fly  1340 TFLY--ACTYELVKHKIPRAALKMD 1362
            .|.|  |.||.|...|.|...:|.:
Worm   390 MFTYVIALTYGLKHVKDPALKIKTE 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020
		PTPc	1100..1345	CDD:214550	56/276 (20%)
		PTPc	1125..1348	CDD:238006	50/244 (20%)
F40G12.10	NP_506537.1	PTPc	144..397	CDD:214550	56/272 (21%)
F40G12.10	NP_506537.1	PTPc_motif	305..397	CDD:214649	26/98 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910