DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp52F and K07F5.8

DIOPT Version :9

Sequence 1:	NP_611093.2	Gene:	Ptp52F / 36790	FlyBaseID:	FBgn0034085	Length:	1433	Species:	Drosophila melanogaster
Sequence 2:	NP_501766.1	Gene:	K07F5.8 / 177833	WormBaseID:	WBGene00010636	Length:	284	Species:	Caenorhabditis elegans

Alignment Length:	245	Identity:	88/245 - (35%)
Similarity:	129/245 - (52%)	Gaps:	29/245 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly  1119 ASELGCHKNRYADIFPYDKNRVILDIDAEGSDYINASFIDGHTRKKEYIATQGPKPESVMDFWRM 1183
            |.|.|  ||||.|:...|.|||.|. .|...:||:|:::...|..|.:|.||.|..::..|||.|
Worm    16 AQEHG--KNRYKDVGCLDNNRVKLG-GAWPHEYIHANYVSTPTNPKRFICTQAPLEKTCADFWFM 77

  Fly  1184 ILQYNVRVIVQVTQFREGNTIKCHEYYP---------YNVRGLTVTIK--SKEVLELYD------ 1231
            .||..|..|..:..::|....|||||.|         :..:|..||:|  |.:.::..|
Worm    78 CLQDRVETIFMLCNYKEKGAKKCHEYLPTEDNKDTMSFKEKGQKVTVKFESSKAIKFRDNSAAKV 142

  Fly  1232 -RTELTVVHDKYGL-KEKVIHYYFKKWPDHGVPEDPMHLIMFVKKVKAEKRPSYSPIVVHCSAGV 1294
             :|.|||  :..|. |.||.||::..|||.|||.....::..::|.:..|    .||.||||||:
Worm   143 TKTVLTV--EGAGCDKLKVNHYHWIDWPDRGVPTADNAILELLEKARVSK----GPIAVHCSAGI 201

  Fly  1295 GRTGTFIGLDLIMQRLKSESKI-NIFETVKKLRFQRMKMVQTQQQYTFLY 1343
            ||||:.:.|:.:|.:|.:...| :..:.::|:|.||...|||..||.|::
Worm   202 GRTGSVVMLEYVMDQLLAGQIIEDTDKIIQKIREQRNNSVQTDHQYLFVH 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020
		PTPc	1100..1345	CDD:214550	88/245 (36%)
		PTPc	1125..1348	CDD:238006	85/239 (36%)
K07F5.8	NP_501766.1	Y_phosphatase	19..256	CDD:278528	86/242 (36%)
K07F5.8	NP_501766.1	PTPc	20..256	CDD:238006	86/241 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910