DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp52F and F57H12.5

DIOPT Version :9

Sequence 1:	NP_611093.2	Gene:	Ptp52F / 36790	FlyBaseID:	FBgn0034085	Length:	1433	Species:	Drosophila melanogaster
Sequence 2:	NP_501331.1	Gene:	F57H12.5 / 177592	WormBaseID:	WBGene00019020	Length:	543	Species:	Caenorhabditis elegans

Alignment Length:	333	Identity:	83/333 - (24%)
Similarity:	136/333 - (40%)	Gaps:	54/333 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly  1062 VRKRLAWKRDSGQGIEDPFGNVIAKNFAIFYTEVAKPEKLAREFKEI-------TVVALELSYSA 1119
            |:|:.: |:.|.|..:...|...|.||.....::   :|:..||..:       |..|.|.:...
Worm   186 VKKKHS-KKHSKQKTKMWLGMPSALNFCNKNNDI---QKIREEFGFLDSLVCNKTTEAFEANKVR 246

  Fly  1120 SELGCHKNRYADIFPYDKNRVILDIDA-EGSDYINASFI---DGHTR------------------ 1162
            :..||.|       .||:|||.|:... |..:|||||.|   |...|
Worm   247 NREGCPK-------IYDENRVQLNRPGHEDVNYINASVITLTDVCRRMACVPAYVHLVVLYFVIF 304

  Fly  1163 --KKEYIATQGPKPES---VMDFWRMILQYNVRVI-VQVTQFREGNTIKC---HEYYPYNVRGLT 1218
              :.:.|..|.|:.|:   |.|||.||.|..:.:: :.|...:..||...   .|...|...| .
Worm   305 QFEHKLIVAQLPQMENESFVEDFWYMIYQEQIHLVYLMVPDDKLKNTTTSLFNDENGGYQYTG-K 368

  Fly  1219 VTIKSKEVLELYDRTELTVVHDKYGLKEKVI---HYYFKKWPDHGVPEDPMHLIMFVKKVKAEKR 1280
            :.|.::......|..|.|:.....|..:.||   |:: ..|.....|...:.:|..:.:..:||:
Worm   369 MFINNRRADVSGDPKEYTIEVLPEGNSDSVICQVHHH-APWKHLQQPPKTLPIIKMIHQFLSEKQ 432

  Fly  1281 PSYSPIVVHCSAGVGRTGTFIGLDLIMQRLKSESKINIFETVKKLRFQRMKMVQTQQQYTFLYAC 1345
            ...:.:.|....|.||..:|||....:.:|.:..:.||.|.:|.::.||...|::..||..:||.
Worm   433 VQNAGVCVVSLFGCGRACSFIGALYAINQLNNGIEPNICEIMKNIKQQRPGGVESFAQYASIYAI 497

  Fly  1346 TYELVKHK 1353
            .::.:..|
Worm   498 VFDYIARK 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020
		PTPc	1100..1345	CDD:214550	72/285 (25%)
		PTPc	1125..1348	CDD:238006	65/256 (25%)
F57H12.5	NP_501331.1	PTPc	220..500	CDD:214550	73/288 (25%)
F57H12.5	NP_501331.1	PTPc	255..498	CDD:304379	64/244 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910