DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp52F and C17H12.3

DIOPT Version :9

Sequence 1:	NP_611093.2	Gene:	Ptp52F / 36790	FlyBaseID:	FBgn0034085	Length:	1433	Species:	Drosophila melanogaster
Sequence 2:	NP_001379692.1	Gene:	C17H12.3 / 177443	WormBaseID:	WBGene00015929	Length:	374	Species:	Caenorhabditis elegans

Alignment Length:	283	Identity:	96/283 - (33%)
Similarity:	143/283 - (50%)	Gaps:	28/283 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly  1099 EKLAREFK--------EITVVALELSYSASELGCHKNRYADIFPYDKNRVILDIDAEGSDYINAS 1155
            |||..||:        ::|..|...:.||: :...||||||:...|:|.|::......|||::|:
Worm    76 EKLRDEFRQMAKYTRPDMTQNAFNANQSAN-INETKNRYADVPCQDQNIVLVAKPPAPSDYVHAN 139

  Fly  1156 FID-GHTRKKEYIATQGPKPESVMDFWRMILQYNVRVIVQVTQFREGNTIKCHEYYPYNVRGLTV 1219
            |:. .....|.:|.||||...:|.|||.||:|..|..||.:.:..|....||.:|:|. ..|...
Worm   140 FVGCPMVPDKRFICTQGPLDHTVDDFWWMIVQQKVEQIVMLCKTIETGKYKCAQYWPL-AMGEKK 203

  Fly  1220 TIKSKEVLELYDRT---------ELTVVHDKYG-LKEKVIHYYFKKWPDHGVPEDPMHLIMFVKK 1274
            .:|...|:|....|         ::|.:...:| .|..|.|.::..|||.|||...:..:..:..
Worm   204 EVKGGIVVENVSGTKPMDRDAEIQITTLQVSFGDQKMSVRHLHWSDWPDRGVPPCKLTSLELLSA 268

  Fly  1275 VKAEKRPSYSPIVVHCSAGVGRTGTFIGLDLIMQRLKSESKI-NIFETVKKLRFQRMKMVQTQQQ 1338
            |    |.|..|||||||||:|||||.:.::.|::|:....:. .:.:.||.||.||...:||..|
Worm   269 V----RGSRVPIVVHCSAGIGRTGTIVAIEYILERIAENKQCPPMPDLVKSLRDQRAYSIQTDMQ 329

  Fly  1339 YTFLY--ACTYELVKHKIPRAAL 1359
            |.:::  ...|.|.|:|...|||
Worm   330 YLYIHRVMLNYFLEKYKDKYAAL 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020
		PTPc	1100..1345	CDD:214550	88/266 (33%)
		PTPc	1125..1348	CDD:238006	80/236 (34%)
C17H12.3	NP_001379692.1	PTPc	77..339	CDD:214550	88/267 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910