Protein Alignment Ptp52F and Y69A2AR.19

DIOPT Version :9

• Sequence 1: NP_611093.2
• Gene: Ptp52F / 36790
• FlyBaseID: FBgn0034085
• Length: 1433
• Species: Drosophila melanogaster
• Sequence 2: NP_500211.3
• Gene: Y69A2AR.19 / 177036
• WormBaseID: WBGene00022090
• Length: 1338
• Species: Caenorhabditis elegans
• Alignment Length: 1372
• Identity: 279/1372 - (20%)
• Similarity: 461/1372 - (33%)
• Gaps: 475/1372 - (34%)

  Fly   193 ITLDTRNNASVVVDTDATDVDTQYAEPGDLVMNVTNLASGITM---ITWGDPSEKNCISNYVFKW 254
            |..||.|||..|....|......|.....|:.::.|   ||.:   :..|.......:|..:
 Worm   150 IPSDTSNNAGRVARQVAPSKSADYLNHTTLIAHIAN---GIALQAGLMKGSIPIDAAVSELL--- 208

  Fly   255 QRNDCGTDQNQDTTTDVPS--TETTNEIDYVTTTPMETTPDTPSDEVKCEWT----------DVS 307
               :.|:.:..|.|...|.  |....::..|..:.:.|.|....:....:|.          ||:
 Worm   209 ---NFGSVKVSDITAFKPDQITALIGKLKGVPASLVSTDPIVTLETRALDWNKLLIASKSIGDVA 270

  Fly   308 S-DGKLREYLLTDLQGCDLYTFQVFINENSTAKASQTFTSAEKLVSAVYEPSPTAYPTQLHWTWF 371
            | .||       |....:|..|:...|.:|.:|.:.|..|..|..|.:.:.|.|::
 Worm   271 SLPGK-------DDFSTELAKFENTFNFDSLSKTADTINSTIKSCSNLLDKSDTSW--------- 319

  Fly   372 SPQNHPKCVANYSVTLTGPIQRSENKTMNVITEET--------FAIFDDLDPCGIYLVE------ 422
              ::|.   |.....|.|.::...:|...:|..:.        |..|..|:.. ::|||
 Worm   320 --ESHS---AIRFKDLPGTLETLGSKVKEIINMDVSFDKLMNGFTAFQPLERL-MHLVELRRSYI 378

  Fly   423 IVP-------------------------------NQLNGSAGTKYQEQSTVG-----EDQPSVIQ 451
            |||                               :.|....|:|.:.:.:||     .:...:::
 Worm   379 IVPVSNTPDITSNLKKVVEQVALAKAAGKSSMTVSALADVGGSKPKREHSVGFQSGISELKQLVK 443

  Fly   452 D----------PVVEAE----AYSMEVSWKTPEYADLCIDGYRLSGWMEDDKLVEVEALSITTQN 502
            |          .|..|:    |..::..:||.:         :||  ..:|||..:  :|.:.|.
 Worm   444 DVLDPWFSSLLNVTSAQQNNLADGLQSLFKTTD---------QLS--RMNDKLKPI--VSSSVQQ 495

  Fly   503 TTVVFDKNLLACQVYIIQIIPYTKEN------------------LDGQLRQVGVETKAAIVDYTK 549
            |..||       ||.:.:|...:.::                  :|.| |.||||....|   ..
 Worm   496 TIAVF-------QVLVNEISLLSSDSAEMSSVMAELDKCSRTLPMDDQ-RVVGVELMKHI---NS 549

  Fly   550 VKLEMKNAGSEFI-------------DLIAFNADYNNS---CPTIFALFTCNATTQVRNPYAERY 598
            :||.:    |:|.             ::.:|...|..|   .||..|       |:|:     ..
 Worm   550 LKLSL----SQFAEFKTSTILNSLEKEITSFQNSYKFSDLQDPTATA-------TEVK-----AV 598

  Fly   599 VEGHSKQGFNASLSPLSPYATYVCK------------VILYNVAGPSEPVVDA----------DM 641
            ||...|.|   ||.....|...:.|            |||..:......:.|:          .:
 Worm   599 VESIQKSG---SLEKFKQYLLLLQKTFADVDGNNLKTVILGGIKARITKIGDSTFGDFIKEELKV 660

  Fly   642 HTTTYFPEQP-----------------ESVMLEK-----STVSSLLFNWQPPTYTNGPIKYYQAF 684
            ||.....|:.                 :..|||:     |.|||.
 Worm   661 HTCLKAQEEQSRKLSQAIQATQSLRKLDEKMLEEVGSAASAVSSF-------------------- 705

  Fly   685 LMRHEASYFVPADCAIVE---QDTKSETKGDPSVNFTGLAPAVRYMMQVAAQNDFGMGVYTEPVI 746
                      ..|.|.::   :..|.|.|| .|.:..|:|.|.:.
 Worm   706 ----------AKDLATIKSIPETMKKEAKG-VSTDLNGMADAKKN-------------------- 739

  Fly   747 GITLPAVSDSVTQLTVLTQGPVNNNAVYEANVTITWKVPCKSNGDIEYFQLAFNGTRNNFAPVSF 811
                   ||||.|         :.:::.:|:..|..:...|   :::.|....:|..........
 Worm   740 -------SDSVGQ---------SVSSLQDASELIELESAIK---ELKGFGPEIDGYIKAVKSPED 785

  Fly   812 ERRVELDTGNKQGRMSYTETEMQPQFDYTVEVSVKNRDVEQLSSSVPGSWQSP-AGLPTIP---- 871
            .:.:|...||....|:..|:.::....:..::.|.       .:.....:.:| |.|..:|
 Worm   786 RKAIETQWGNHHSDMASLESGLKAAKGFVDKIDVS-------KAKTMSDYGTPLANLKDLPDVKI 843

  Fly   872 -SDELIKQMRANVEETSNPTKTAIVRLPADIMTSASGDIKWMALMISQKNCAGVPHLKYDVSSDW 935
             :.|.||.:.|.::....|.:......|..:|.:|...::.:|.:              |:....
 Worm   844 NALEKIKALDALIKALPPPKRKRATSDPKTVMEAAKSTLEKIAAL--------------DLQFSN 894

  Fly   936 PKVLSYQEAGA--DGTGDCSLEYQTTEERWHPEPVQRQRRDGEVTSDEEIVFTIGLDKCSEVQKT 998
            .|. .||:|.|  ....|...::..|                                      |
 Worm   895 HKT-QYQQAPAAFKAFHDFLAKFLVT--------------------------------------T 920

  Fly   999 YCNGPLLPDTDYNVVVRLFTASGYSDAAVLNFKTKAAIKVTLILVSVCSCL-LLAFVLGL--TVL 1060
            :.|                 ::|.||         :.|.:|||::.|.|.| |:...:|:  .|.
 Worm   921 HSN-----------------STGGSD---------SGISITLIIIIVGSILALIGVAVGIYFGVR 959

  Fly  1061 WVRKRLA----------W-KRDSGQGIEDPFGNVIAKNFAIFYTEVAKPEKLAREFKEITVVALE 1114
            |..|:.|          | |..:.:.:|.....::|....::.|:              |.|::|
 Worm   960 WYEKKKAAEQMEHEIVVWVKAQAYKSLEAAIIVLVASLHVVWGTQ--------------TSVSVE 1010

  Fly  1115 LSYSASELGCHKNRYADIFPYDKNR----------VILDIDAEG------SDYINAS-FIDGHTR 1162
            .|          |.|   .|.:|||          ..:::.::|      :::||.| .:||:|:
 Worm  1011 KS----------NAY---LPKEKNRRPLATPCNPETAVEVMSDGTRIPIHANWINTSPDVDGNTQ 1062

  Fly  1163 KKEYIATQGPKPESVMDFWRMILQYNVRVIVQVTQFREGNTIKCHEYYPYNVRGLTVTI---KSK 1224
            |  :||||||.|.:..|||.|:..:.|..:|.:.||.|....|||||:|... |..|.:   |.|
 Worm  1063 K--FIATQGPLPNTSDDFWTMVQFHKVETVVMLCQFVEKEEEKCHEYFPVRT-GQIVDLERYKLK 1124

  Fly  1225 EVLE---LYDRTELTVVHDKYGLKE----KVIHYYFKKWPDHGVPEDPMHLIMFVKKVKAEKRPS 1282
            .|.:   |.|.|....:..:...||    .:.||.:..|||.|:|:........:...|..|:
 Worm  1125 TVTQEQILGDSTSKRTIQVEDTSKEFPTRTITHYQYHSWPDQGIPQGHAQCFDLMNMAKESKK-- 1187

  Fly  1283 YSPIVVHCSAGVGRTGTFIGLDLIMQRLKSESKINIFETVKKLRFQRMKMVQT-QQQYTFLYACT 1346
              |||||||||:|||.:||....|...:.:...:.:.:.|.:||.||...:|| :|.|.......
 Worm  1188 --PIVVHCSAGIGRTVSFIATQYIPSAVLANRTLVLNQAVAELRDQRWCAIQTVEQMYWVQVGSV 1250

  Fly  1347 YELVKHK 1353
            |.|.|.|
 Worm  1251 YRLSKEK 1257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020	18/125 (14%)
		PTPc	1100..1345	CDD:214550	83/272 (31%)
		PTPc	1125..1348	CDD:238006	79/250 (32%)
Y69A2AR.19	NP_500211.3	WSN	172..234	CDD:280385	12/70 (17%)
		Y_phosphatase	1018..1245	CDD:278528	76/233 (33%)
		PTPc	1019..1245	CDD:238006	76/232 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910