DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp52F and F20H11.4

DIOPT Version :9

Sequence 1:	NP_611093.2	Gene:	Ptp52F / 36790	FlyBaseID:	FBgn0034085	Length:	1433	Species:	Drosophila melanogaster
Sequence 2:	NP_498458.1	Gene:	F20H11.4 / 175937	WormBaseID:	WBGene00017647	Length:	446	Species:	Caenorhabditis elegans

Alignment Length:	292	Identity:	87/292 - (29%)
Similarity:	141/292 - (48%)	Gaps:	32/292 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly  1091 FYTEVAKPEKLAREFKEITVVALELSYS--ASELGCH--KNRYADIFPYDKNRVILDIDAEGSDY 1151
            |:.:....:||.|:|     |||....:  |..:..|  |.||.||...|..||:|......:|:
Worm   111 FFVDELDCKKLMRDF-----VALRAPSTCVADTMKKHSEKCRYYDILCPDATRVVLQNRPPDNDF 170

  Fly  1152 INASFIDGHTRKKEYIATQGPKPESVMDFWRMILQYNVRVIVQVTQFREGNTIKCHEYYP----- 1211
            |:|:::. ...|..||:.|||..::|.|||.|:.......:|.:..:.|....||..|.|
Worm   171 IHANWMT-MPDKFRYISAQGPMDQTVEDFWHMVYTEKAPAVVMICDWEEDGIQKCSRYIPSEDNI 234

  Fly  1212 YNVRGLTVTIKSKEVLELY-----DRTELTVVHDKYGLKEKVI-HYYFKKWPDHGVPEDPMHLIM 1270
            .:|.|:....|..::..:|     ...|::|..........|: ||:|.||.||..|...:.::.
Worm   235 SHVCGIYRITKIDQMTMVYADVALQSFEISVTDKSLECPSLVVKHYHFLKWRDHTAPMTSISVLK 299

  Fly  1271 FVKKVKAEKRPSYSPIVVHCSAGVGRTGTFIGLDLIMQRLKSESKINIFETVKKLRFQRMKMVQT 1335
            .:|.::..|||  .|.|:|||||:|||.|.||:|...||:....::|:.:.|:::|..|.|.||:
Worm   300 LLKALRDPKRP--GPPVIHCSAGIGRTATLIGVDYGNQRIGEVGEMNVLDIVREMRQMRDKAVQS 362

  Fly  1336 QQQYTFLYACTYELVKHKIPRAALKMDGRPKS 1367
            ..|:.|:..|..:         .:.:||.|::
Worm   363 HHQFIFMLMCIAD---------RMVLDGVPQN 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020
		PTPc	1100..1345	CDD:214550	82/259 (32%)
		PTPc	1125..1348	CDD:238006	75/235 (32%)
F20H11.4	NP_498458.1	Y_phosphatase	142..375	CDD:278528	75/235 (32%)
F20H11.4	NP_498458.1	PTPc	144..375	CDD:238006	74/233 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19134
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	4	3.970