DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp52F and egg-5

DIOPT Version :9

Sequence 1:	NP_611093.2	Gene:	Ptp52F / 36790	FlyBaseID:	FBgn0034085	Length:	1433	Species:	Drosophila melanogaster
Sequence 2:	NP_491316.1	Gene:	egg-5 / 172007	WormBaseID:	WBGene00020035	Length:	753	Species:	Caenorhabditis elegans

Alignment Length:	361	Identity:	78/361 - (21%)
Similarity:	125/361 - (34%)	Gaps:	105/361 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly  1104 EFKEITVVALELSYSASELGCHKNRYADIFPYDKNRVILDIDAEG---SDYINASFIDGHTRKKE 1165
            |..|.:|..:..::|||:....|.|...:...|..|:.|.. ..|   .|:|:|:.|.|.....|
Worm   413 EILENSVNHIPFTHSASDNNQEKCRNPRVHCRDSTRIALQF-PRGQYLGDFIHANRISGKPLFNE 476

  Fly  1166 YIATQGPKPESVMDFWRMILQYNVRVIVQVTQFREGNTIKCHEYYPYNVRGLTVTIKSKEVLELY 1230
            :|.||.|...:|.|||||:.|..|..||.:|..:|..  :|..|:|.:.....||:.....:|.:
Worm   477 FIMTQAPMKNTVDDFWRMVWQEEVPYIVMLTSRKEPE--RCEYYWPKSPSDPAVTVPGGLRIENF 539

  Fly  1231 --------------------DRTELTVVHDKYGLKEKVIHYYFKKWPDHGVPEDPMHLIMFVKKV 1275
                                ||.|..|.|.:..:......|            .|::::..:
Worm   540 GVYQAPDPLFRVTHLRLIGPDREERHVEHWQGDVNNSSNMY------------SPLNILRLL--- 589

  Fly  1276 KAEKRPSYSPIVVHCSAGVGRTGTFIGLDL-IMQRLKSES-KINIFETVKKLRFQRMKMVQTQQQ 1338
                |.:..|:|:|...||.|....:..:: |...|:..: |..:...|:.||.:|...::|..|
Worm   590 ----RNASKPVVIHDHLGVSRAACLVAAEIAICSLLRGPTYKYPVQRAVQFLRQRRPFSIETPMQ 650

  Fly  1339 YTFLYACT----------------------------------------YELVKHKIPRAALKMDG 1363
            |.|::...                                        |.|:..:.....::|.|
Worm   651 YIFVHRLVAFFFRDVIGSAKELDVDYERWLQERSERMFLDDLAAPIPGYRLLSPRADPDIVRMVG 715

  Fly  1364 RP------------------KSVTVPAIPSPKKVSF 1381
            ||                  |...|..|.||.|..|
Worm   716 RPERPNYRREAPDCVGEMPNKVAAVDGILSPAKSVF 751

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020
		PTPc	1100..1345	CDD:214550	65/265 (25%)
		PTPc	1125..1348	CDD:238006	59/287 (21%)
egg-5	NP_491316.1	PTPc	407..660	CDD:214550	65/268 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910