DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ptp52F and F47B3.7

DIOPT Version :9

Sequence 1:	NP_611093.2	Gene:	Ptp52F / 36790	FlyBaseID:	FBgn0034085	Length:	1433	Species:	Drosophila melanogaster
Sequence 2:	NP_491276.1	Gene:	F47B3.7 / 171983	WormBaseID:	WBGene00018531	Length:	374	Species:	Caenorhabditis elegans

Alignment Length:	276	Identity:	96/276 - (34%)
Similarity:	143/276 - (51%)	Gaps:	33/276 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly  1100 KLAREFKEITVVALELSYSASELGCHKNRYADIFPYDKNRVILDIDAEGSDYINASFIDGHTRKK 1164
            ||..||.|:......:...|.:....||||.||...:|.||||..|...||||:|:::....:.|
Worm    67 KLRDEFSEVANKNPNVPVDAFKSNPEKNRYTDIKCIEKTRVILTTDGASSDYIHANYVGISIKPK 131

  Fly  1165 EYIATQGPKPESVMDFWRMILQYNVRVIVQVTQFREGNTIKCHEYYP--------YNVRGLTVTI 1221
            ::|.|||||..::.|||.|::|.||..|:.:.:..|...:||.:|:|        |..:|.|:||
Worm   132 KFICTQGPKDSTIYDFWAMVIQDNVESIIMLCKVIELARVKCEQYWPAVEGQTNTYVSKGHTITI 196

  Fly  1222 KSKEVLEL------YDRTELTVVHDKYGLKEKVIHYYFKKWPDHGVPEDPMHLIMFVKKVKAEKR 1280
            .:..|..|      .:.|.|.:|.  .|....:.||.:..|||||.|...|..|..::.|..:.
Worm   197 NNLGVGTLSPDDDFINVTNLELVW--AGKTRSITHYQWTNWPDHGAPPINMGAINLIEAVNYDT- 258

  Fly  1281 PSYSPIVVHCSAGVGRTGTFIGLDLIMQRL------KSESKINIFETVKKLRFQRMKMVQTQQQY 1339
               :|:||||||||||:||.:|:.|||.::      |...|:     |:::|.||...:||:.||
Worm   259 ---NPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCKDMKKL-----VEEIRNQRHYAIQTEAQY 315

  Fly  1340 TFLY--ACTYELVKHK 1353
            .:::  ...|.|..||
Worm   316 MYIHRVLLEYFLELHK 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020
		PTPc	1100..1345	CDD:214550	92/266 (35%)
		PTPc	1125..1348	CDD:238006	86/244 (35%)
F47B3.7	NP_491276.1	Y_phosphatase	90..324	CDD:278528	86/244 (35%)
F47B3.7	NP_491276.1	PTPc	92..324	CDD:238006	86/242 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910