DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8435 and RGD1560857

DIOPT Version :9

Sequence 1:	NP_611092.2	Gene:	CG8435 / 36789	FlyBaseID:	FBgn0034084	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	XP_038950951.1	Gene:	RGD1560857 / 317036	RGDID:	1560857	Length:	313	Species:	Rattus norvegicus

Alignment Length:	337	Identity:	165/337 - (48%)
Similarity:	217/337 - (64%)	Gaps:	29/337 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSERKVLNKYYPPDFDPSKIPRMKLAKNRQYTVRLMAPFNMRCKTCGEYIYKGKKFNARKEDVEN 65
            |||||||||||||||||||||::||.|:|||.|||||||||||||||||||||||||||||.|:|
  Rat     1 MSERKVLNKYYPPDFDPSKIPKLKLPKDRQYVVRLMAPFNMRCKTCGEYIYKGKKFNARKETVQN 65

  Fly    66 ETYLGIRIYRFYIKCTRCLQEISFKTDPQNTDYEIEAGATRNFMALKLAEEQARREEQELRDEEA 130
            |.|||:.|:||||||||||.||:|||||:||||.:|.||||||.|.||.|::.:|.::|..|||.
  Rat    66 EAYLGLPIFRFYIKCTRCLAEITFKTDPENTDYTMEHGATRNFQAEKLLEQEEKRMQKEREDEEL 130

  Fly   131 NNPMKLLENRTQQSRNEIETIESLEELRDLNRRQQTVDYNTLLQQY--NTVETERERQEREERED 193
            |||||:|||.|:.|:.|:|.:|:|:||:|||:||..||:..:|.|:  :..:.:::::|.:|||.
  Rat   131 NNPMKVLENCTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLLQHRLSQEQWQQQQEEEDERET 195

  Fly   194 EDFIKSVNFKNKPEGSSRVVAEEIIEEIKDEPLDTPSAPPPAKQAKPSTISLSATSSSKASAAQS 258
            ...::...::            .::::...|....||.|..|.:..|:.| |.....:|.. |:.
  Rat   196 VALLEEARYR------------RLLDDSDSEDEAPPSRPQAAARPNPTAI-LDEVPKTKRK-AEG 246

  Fly   259 MVKRKTPLVLVKPKATAVAKPTVATGTTQVESKPAATTPSVVSAPAETKATNQPAAAP--AGLSL 321
            :.::.....||.||.   ||.....|:.||.   ..||    .||...|..|.....|  :.||.
  Rat   247 LCRKAQLAGLVIPKK---AKTEANRGSEQVR---VPTT----GAPESRKVANPAPQTPGASSLSQ 301

  Fly   322 LAAYSDSSEDSN 333
            |.||.| ||||:
  Rat   302 LCAYGD-SEDSD 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8435	NP_611092.2	COG5134	7..>170	CDD:227463	117/162 (72%)
CG8435	NP_611092.2	DUF572	8..>177	CDD:282371	118/170 (69%)
RGD1560857	XP_038950951.1	DUF572	9..310	CDD:398281	154/325 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	278	1.000	Domainoid score	I1638
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6350
Inparanoid	1	1.050	294	1.000	Inparanoid score	I2673
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002595
OrthoInspector	1	1.000	-	-		otm46350
orthoMCL	1	0.900	-	-		OOG6_102870
Panther	1	1.100	-	-	O	PTHR12111
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1951
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.960