DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lbk and RLP38

DIOPT Version :9

Sequence 1:	NP_611091.2	Gene:	lbk / 36788	FlyBaseID:	FBgn0034083	Length:	1252	Species:	Drosophila melanogaster
Sequence 2:	NP_188953.1	Gene:	RLP38 / 821887	AraportID:	AT3G23120	Length:	784	Species:	Arabidopsis thaliana

Alignment Length:	511	Identity:	123/511 - (24%)
Similarity:	200/511 - (39%)	Gaps:	119/511 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   259 NKYN--IDCPKDCKCLNVLFDCDKLHLERVPVLPSYVQTLHLANNKLNDTTVLEIRNLLNLTKVS 321
            |.:|  |||   |....|  .||.: |..|..|..|.  |..|:..|..::.|  ..|.:||.:.
plant    62 NPWNKGIDC---CSWGGV--TCDAI-LGEVISLKLYF--LSTASTSLKSSSAL--FKLQHLTHLD 116

  Fly   322 LKR-NLLEVIPKFI-GLSGLKHLVLANNHITSISSESLAALPLLRTLDLSRNKLHTIELNSFPKS 384
            |.. ||...||..| .||.|.||.|:.||:......|:..|..|..:||..|.|.    .:.|.|
plant   117 LSNCNLQGEIPSSIENLSHLTHLDLSTNHLVGEVPASIGNLNQLEYIDLRGNHLR----GNIPTS 177

  Fly   385 -NNLVHLILSFNEITNVNEHSFA----TLNNLTD---LELSNNRLST------------------ 423
             .||..|     .:.:::|::|.    .|:|||.   |:||:|...:
plant   178 FANLTKL-----SLLDLHENNFTGGDIVLSNLTSLAILDLSSNHFKSFFSADLSGLHNLEQIFGN 237

  Fly   424 -------LPIRVFKNLNQLKKLALNFNQLE--INWSTFRGLESMKNLQLKSNKIRALQDGVFYVM 479
                   .|..:.| ::.|.|:.|:.||.|  |::........:..|.:..|............:
plant   238 ENSFVGLFPASLLK-ISSLDKIQLSQNQFEGPIDFGNTSSSSRLTMLDISHNNFIGRVPSSLSKL 301

  Fly   480 HKIETIDLAMNQISSLSRQGLFNLTKLRHLNLSFNAI-SRIEVDTWEFTQSLEVLDLSNNAINEF 543
            ..:|.:||:.|....||.:.:..|..|..|::|:|.: .::....|: ..:|:.:|||:|:..:.
plant   302 VNLELLDLSHNNFRGLSPRSISKLVNLTSLDISYNKLEGQVPYFIWK-PSNLQSVDLSHNSFFDL 365

  Fly   544 KPQHLDCLH--RLKTLNLAHNRLQ----------------YLQENTF-----DCVKN---LEELN 582
             .:.::.::  :|..|||..|.||                .|.:|.|     .|:||   ...||
plant   366 -GKSVEVVNGAKLVGLNLGSNSLQGPIPQWICNFRFVFFLDLSDNRFTGSIPQCLKNSTDFNTLN 429

  Fly   583 LRRNRLSWIIEDQSAAAPFKGLRKLRRLDLHGNNLKQISTKAMSGLNNLEILNLGSNALAS---- 643
            ||.|.||..:.:....:..     ||.||:..||......|::....::|.||:..|.:..
plant   430 LRNNSLSGFLPELCMDSTM-----LRSLDVSYNNFVGKLPKSLMNCQDMEFLNVRGNKIKDTFPF 489

  Fly   644 ------------IQVNAFEHML----------RLNKLVFKSLNFICDCDLVWFQQW 677
                        ::.|||...:          ||:.:...:.:|:......:|..|
plant   490 WLGSRKSLMVLVLRSNAFYGPVYNSTTYLGFPRLSIIDISNNDFVGSLPQDYFANW 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lbk	NP_611091.2	LRR_RI	<275..446	CDD:238064	56/205 (27%)
		leucine-rich repeat	293..316	CDD:275380	5/22 (23%)
		LRR_8	316..373	CDD:290566	22/58 (38%)
		leucine-rich repeat	317..338	CDD:275380	9/22 (41%)
		leucine-rich repeat	339..362	CDD:275380	8/22 (36%)
		leucine-rich repeat	363..386	CDD:275380	7/23 (30%)
		LRR_8	386..445	CDD:290566	19/90 (21%)
		leucine-rich repeat	387..410	CDD:275380	5/26 (19%)
		leucine-rich repeat	411..434	CDD:275380	8/50 (16%)
		leucine-rich repeat	435..457	CDD:275380	7/23 (30%)
		LRR_8	457..516	CDD:290566	13/58 (22%)
		leucine-rich repeat	458..481	CDD:275380	2/22 (9%)
		leucine-rich repeat	482..505	CDD:275380	7/22 (32%)
		LRR_RI	<498..669	CDD:238064	48/223 (22%)
		LRR_8	504..564	CDD:290566	15/62 (24%)
		leucine-rich repeat	506..529	CDD:275380	5/23 (22%)
		leucine-rich repeat	530..553	CDD:275380	5/24 (21%)
		leucine-rich repeat	554..577	CDD:275380	11/43 (26%)
		LRR_8	576..641	CDD:290566	20/67 (30%)
		leucine-rich repeat	578..604	CDD:275380	7/25 (28%)
		leucine-rich repeat	607..630	CDD:275380	7/22 (32%)
		leucine-rich repeat	631..652	CDD:275380	7/36 (19%)
		LRRCT	665..712	CDD:214507	3/13 (23%)
		IG	734..823	CDD:214652
		Ig	735..823	CDD:143165
		I-set	834..924	CDD:254352
		Ig	851..924	CDD:299845
		IG	936..1027	CDD:214652
		Ig	961..1020	CDD:143165
RLP38	NP_188953.1	PLN00113	11..>721	CDD:331614	123/511 (24%)
		leucine-rich repeat	112..135	CDD:275380	9/22 (41%)
		leucine-rich repeat	136..159	CDD:275380	8/22 (36%)
		leucine-rich repeat	160..183	CDD:275380	9/26 (35%)
		leucine-rich repeat	184..206	CDD:275380	6/26 (23%)
		leucine-rich repeat	207..254	CDD:275380	6/47 (13%)
		leucine-rich repeat	255..276	CDD:275380	7/20 (35%)
		leucine-rich repeat	280..303	CDD:275380	2/22 (9%)
		leucine-rich repeat	304..327	CDD:275380	7/22 (32%)
		leucine-rich repeat	352..376	CDD:275380	5/24 (21%)
		leucine-rich repeat	377..397	CDD:275380	7/19 (37%)
		leucine-rich repeat	401..424	CDD:275380	6/22 (27%)
		leucine-rich repeat	425..448	CDD:275380	7/22 (32%)
		leucine-rich repeat	449..472	CDD:275380	7/22 (32%)
		leucine-rich repeat	473..496	CDD:275380	4/22 (18%)
		leucine-rich repeat	523..545	CDD:275380	3/21 (14%)
		leucine-rich repeat	659..682	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000