DRSC/TRiP Functional Genomics Resources

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Protein Alignment lbk and Fili

DIOPT Version :9

Sequence 1:NP_611091.2 Gene:lbk / 36788 FlyBaseID:FBgn0034083 Length:1252 Species:Drosophila melanogaster
Sequence 2:NP_001369108.1 Gene:Fili / 5740472 FlyBaseID:FBgn0085397 Length:789 Species:Drosophila melanogaster


Alignment Length:517 Identity:138/517 - (26%)
Similarity:228/517 - (44%) Gaps:73/517 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   265 CPKDCKCL----NVLFDCDKLHLERVPVLPSYVQTLHLANNKLNDTTVLEIRNLLNLTKVSLKRN 325
            ||..|:||    |....|....||.||:             :||..|     ..:||| |:..|.
  Fly    42 CPSKCQCLGGEANSRALCVDAALEDVPI-------------QLNPET-----KYINLT-VNRIRT 87

  Fly   326 LLEVIPKFIGLSGLKHLVLANNHITSISSESLAALPLLRTLDLSRNKLHTIELNSFPKSNNLVHL 390
            |...:|.::   .|:.|.|:.|.|.::.|::......||||:||||.:.::..::|....||:.|
  Fly    88 LEFSLPFYM---KLEILDLSQNIIETLGSKNFEYQSELRTLNLSRNLVSSLHKHAFKGLTNLLLL 149

  Fly   391 ILSFNEITNVNEHSFATLNNLTDLELSNNRLSTLPIRVFKNLNQLKKLALNFNQLEINWSTFRGL 455
            .||||.|..|:..:.:.|.:|.:|:|:||.:.:|....||.:|.|:.|....|:|          
  Fly   150 DLSFNRIETVHPTALSDLASLVELDLTNNNIVSLEDNCFKGMNTLEVLVFRNNRL---------- 204

  Fly   456 ESMKNLQLKSNKIRALQDGVFYVMHKIETIDLAMNQISSLSRQGLFNLTKLRHLNLSFNAISRIE 520
                 |.:.::.:        :.:|.::::|:::|.:..:.......|.:|..|::..|.:|.::
  Fly   205 -----LDVPASNL--------WHLHALKSLDMSLNLVEFVRNDSFEGLKELLALSVQGNVMSELD 256

  Fly   521 VDTWEFTQSLEVLDLSNNAINEFKPQHLDCLHRLKTLNLAHNRLQYLQENTFDCVKNLEELNLRR 585
            :..:|...||:.||||:|.:.....|.|..|..|..|||..||...|....|..:.:|.||:|  
  Fly   257 LSAFEGLISLKHLDLSDNNLTMVPTQQLSKLSNLTYLNLGGNRFSQLPAVAFLNLFHLRELHL-- 319

  Fly   586 NRLSWIIEDQSAAAPFKGLRKLRRLDLHGN-NLKQISTKAMSGLNNLEILNLGSNALASIQVNAF 649
            :||.::....|.|  |.....|:.|.|:.| .|..|..:...|..|:..:.:.||:|.::....|
  Fly   320 SRLDFLQRIDSRA--FVDNTHLQTLHLNNNPQLSDIPMRLFQGNPNILEVYMQSNSLQTLYSAQF 382

  Fly   650 EHMLRLNKLVFKSLNFICDCDLVWFQQWLKNRF---PQQAEHAVCGYPEHLLDRHLKSLSSSELV 711
            . :.:|.||........|:|.|:|..:.:...|   ....|||..|....|    .|.....|| 
  Fly   383 P-VDQLQKLYLGDNPLQCNCSLLWLWRLVTGNFEGVDPGMEHAAGGAVAAL----AKEADDEEL- 441

  Fly   712 CVDSPKPRVEQEPDDMLAVNAANITLECIASS-----PTAASLAAADELKIK--WRHDNQHV 766
               :.:.......||.:|..||.|..:.|.::     |:|..||.:...:..  .|.|.|.:
  Fly   442 ---ADEATAVASTDDGVAALAAYIAEQHIVNALHTTEPSAYELATSSSNRNSGILRMDRQQI 500

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
lbkNP_611091.2 LRR_RI <275..446 CDD:238064 52/170 (31%)
leucine-rich repeat 293..316 CDD:275380 3/22 (14%)
LRR_8 316..373 CDD:290566 21/56 (38%)
leucine-rich repeat 317..338 CDD:275380 6/20 (30%)
leucine-rich repeat 339..362 CDD:275380 6/22 (27%)
leucine-rich repeat 363..386 CDD:275380 9/22 (41%)
LRR_8 386..445 CDD:290566 22/58 (38%)
leucine-rich repeat 387..410 CDD:275380 9/22 (41%)
leucine-rich repeat 411..434 CDD:275380 8/22 (36%)
leucine-rich repeat 435..457 CDD:275380 4/21 (19%)
LRR_8 457..516 CDD:290566 8/58 (14%)
leucine-rich repeat 458..481 CDD:275380 1/22 (5%)
leucine-rich repeat 482..505 CDD:275380 3/22 (14%)
LRR_RI <498..669 CDD:238064 49/171 (29%)
LRR_8 504..564 CDD:290566 20/59 (34%)
leucine-rich repeat 506..529 CDD:275380 5/22 (23%)
leucine-rich repeat 530..553 CDD:275380 9/22 (41%)
leucine-rich repeat 554..577 CDD:275380 8/22 (36%)
LRR_8 576..641 CDD:290566 19/65 (29%)
leucine-rich repeat 578..604 CDD:275380 9/25 (36%)
leucine-rich repeat 607..630 CDD:275380 7/23 (30%)
leucine-rich repeat 631..652 CDD:275380 4/20 (20%)
LRRCT 665..712 CDD:214507 13/49 (27%)
IG 734..823 CDD:214652 9/40 (23%)
Ig 735..823 CDD:143165 9/39 (23%)
I-set 834..924 CDD:254352
Ig 851..924 CDD:299845
IG 936..1027 CDD:214652
Ig 961..1020 CDD:143165
FiliNP_001369108.1 leucine-rich repeat 75..97 CDD:275378 8/30 (27%)
leucine-rich repeat 98..121 CDD:275380 6/22 (27%)
LRR_8 120..180 CDD:404697 24/59 (41%)
leucine-rich repeat 122..145 CDD:275380 9/22 (41%)
leucine-rich repeat 146..169 CDD:275380 9/22 (41%)
LRR <161..>354 CDD:227223 56/219 (26%)
leucine-rich repeat 170..193 CDD:275380 8/22 (36%)
leucine-rich repeat 194..217 CDD:275380 5/45 (11%)
leucine-rich repeat 218..265 CDD:275380 8/46 (17%)
leucine-rich repeat 266..289 CDD:275380 9/22 (41%)
leucine-rich repeat 290..313 CDD:275380 8/22 (36%)
leucine-rich repeat 314..338 CDD:275380 9/27 (33%)
LRR_8 337..397 CDD:404697 15/60 (25%)
leucine-rich repeat 339..360 CDD:275380 6/20 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24373
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.010

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