Protein Alignment lbk and znf534

DIOPT Version :10

• Sequence 1: NP_611091.2
• Gene: lbk / 36788
• FlyBaseID: FBgn0034083
• Length: 1252
• Species: Drosophila melanogaster
• Sequence 2: XP_012823677.1
• Gene: znf534 / 448416
• XenbaseID: XB-GENE-1219092
• Length: 423
• Species: Xenopus tropicalis
• Alignment Length: 512
• Identity: 93/512 - (18%)
• Similarity: 155/512 - (30%)
• Gaps: 184/512 - (35%)

  Fly   706 SSSELVCVDSPKPRVEQEPDDMLAVNAANITLECIASS-------PTAASLAAADELKIKWRHDN 763
            |.||.......||              .|:::|.:..|       |....||:..||
 Frog     6 SPSESAVYSQLKP--------------VNMSVEGVEDSGVFEDIKPAIRMLASQPEL-------- 48

  Fly   764 QHVQERPAVHDGASTETQIRHDLSTNQTSIYGYLRLTNVTYESAGRYQCVVSNAFGTTYAQ-KFK 827
                   :.|:.|..:..:...:..:..|...|.|      |||.    ||...|.....| .:.
 Frog    49 -------SEHERAEMDKYLLSQVPLHILSDKKYRR------ESAS----VVDEFFEAEKPQAPYS 96

  Fly   828 ISIGI---------------HPTFLQVPSNLTLDAGEMARLVCSASGDPT-PE------------ 864
            ::|.:               ..||..:|...|......|: .||||...| |:
 Frog    97 VNINVILPDTAHLRTGLYRPSKTFTVLPQVKTEPGSNFAQ-PCSASLTQTLPDFTSVFSMPHSVA 160

  Fly   865 ---IALQKFGGSEFPAATERRLQVIREENAFLITNAKPSDSGIYTCTALSAAGEIKVNATLVVND 926
               |.:::...||.|.:....:|          ....|......|.:...::|     .|.|||.
 Frog   161 VNNIFIKQEAPSEVPLSAPASIQ----------PQVYPMSMANETLSLAQSSG-----TTSVVNS 210

  Fly   927 ---------------KPQPS-IPLVHQEVVVGRTCVLQCLSETANADFELEHPHREWFKENKPIH 975
                           .|||: |..|.|...:|:..|                |....|..:..:.
 Frog   211 ISGVTMATHNGGPSPLPQPARIQQVKQYQTLGQDVV----------------PVSGQFYHSPGVS 259

  Fly   976 ISPTAPDGDRYYFSNNKELLVILNAQSNDAGHFRCEITDNSRTFTLQSELVVVKENLNWVVLLVG 1040
            :.|:.|:.......|..||:..::...:....|..::.......|:.|.:|        .||..|
 Frog   260 LPPSPPNSQPGSPENQPELMNTISPPPSYEATFGLKLVQPQHIHTVPSSMV--------SVLPQG 316

  Fly  1041 IITVTVICVVVDCCIIWCTLRYQKKKLRMSLAAERHSTQLRPRSL--ADL-GCS--YDEANHRRL 1100
            .:.:||             .:|.:          |::.:|..|.:  .|. |||  |.:::|.:.
 Frog   317 QVIMTV-------------PKYNR----------RNNPELEKRRIHHCDFPGCSKVYTKSSHLKA 358

  Fly  1101 TVMS-TPPSEQRCLEQG----------LTLSYLRQTDLE-----------AQQDHLS 1135
            ...: |.....:|..:|          ||..|.:.|..:           ::.|||:
 Frog   359 HQRTHTGEKPYKCAWEGCDWRFARSDELTRHYRKHTGAKPFKCAACGRCFSRSDHLA 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbk	NP_611091.2	LRR	<293..642	CDD:443914
		leucine-rich repeat	293..316	CDD:275380
		leucine-rich repeat	317..338	CDD:275380
		leucine-rich repeat	339..362	CDD:275380
		leucine-rich repeat	363..386	CDD:275380
		leucine-rich repeat	387..410	CDD:275380
		leucine-rich repeat	411..434	CDD:275380
		leucine-rich repeat	435..457	CDD:275380
		leucine-rich repeat	458..481	CDD:275380
		leucine-rich repeat	482..505	CDD:275380
		leucine-rich repeat	506..529	CDD:275380
		leucine-rich repeat	530..553	CDD:275380
		leucine-rich repeat	554..577	CDD:275380
		leucine-rich repeat	578..604	CDD:275380
		leucine-rich repeat	607..630	CDD:275380
		leucine-rich repeat	631..652	CDD:275380
		LRRCT	665..712	CDD:214507	3/5 (60%)
		Ig_3	717..816	CDD:464046	20/105 (19%)
		Ig	835..924	CDD:472250	20/104 (19%)
		Ig strand B	851..855	CDD:409353	1/3 (33%)
		Ig strand C	864..868	CDD:409353	1/18 (6%)
		Ig strand E	890..894	CDD:409353	0/3 (0%)
		Ig strand F	904..909	CDD:409353	1/4 (25%)
		Ig strand G	917..920	CDD:409353	0/2 (0%)
		Ig_3	927..1013	CDD:464046	16/86 (19%)
znf534	XP_012823677.1	KLF5_N	1..336	CDD:410335	76/431 (18%)
		COG5048	321..>406	CDD:227381	19/107 (18%)
		C2H2 Zn finger	344..363	CDD:275368	5/18 (28%)
		C2H2 Zn finger	371..393	CDD:275368	5/21 (24%)
		zf-H2C2_2	385..410	CDD:463886	4/24 (17%)
		C2H2 Zn finger	401..421	CDD:275368	3/15 (20%)