Protein Alignment lbk and Lrrc32

DIOPT Version :10

• Sequence 1: NP_611091.2
• Gene: lbk / 36788
• FlyBaseID: FBgn0034083
• Length: 1252
• Species: Drosophila melanogaster
• Sequence 2: NP_001106850.1
• Gene: Lrrc32 / 434215
• MGIID: 93882
• Length: 663
• Species: Mus musculus
• Alignment Length: 460
• Identity: 126/460 - (27%)
• Similarity: 198/460 - (43%)
• Gaps: 97/460 - (21%)

  Fly   269 CKCLNVLFDCDKLHLERVP-VLPSYVQTLHLANNKLNDTTVLEIRNLLNLTKVSLKRNLLEVIPK 332
            |:.:|....|..|.|.:|| ||...:|.|:|:.|:|....|..:.....|..:.|..|.:..:..
Mouse    27 CRTVNKEALCHGLGLLQVPSVLSLDIQALYLSGNQLQSILVSPLGFYTALRHLDLSDNQISFLQA 91

  Fly   333 --FIGLSGLKHLVLANNHIT---SISSESLAALPLLRTLDLSRNKLH--TIE--LNSFPK----- 383
              |..|..|:||.||:|.:.   :::|..|..||||.:||||.|.||  .:|  |...|:
Mouse    92 GVFQALPYLEHLNLAHNRLATGMALNSGGLGRLPLLVSLDLSGNSLHGNLVERLLGETPRLRTLS 156

  Fly   384 --SNNLVHLI--------------LSFNEITNVNEHSFATLNNLTDLELSNNRLSTLPIRVFKNL 432
              .|:|..|.              |..|.:.::.:.:|..|.:||.|.||.|.|:.  |..| :|
Mouse   157 LAENSLTRLARHTFWGMPAVEQLDLHSNVLMDIEDGAFEALPHLTHLNLSRNSLTC--ISDF-SL 218

  Fly   433 NQLKKLALNFN-------------QLEINWSTFRGLESMKNLQLKSNKIRALQD-GVF----YVM 479
            .||:.|.|:.|             |.::.|           |.|:.||:....| .||    |:.
Mouse   219 QQLQVLDLSCNSIEAFQTAPEPQAQFQLAW-----------LDLRENKLLHFPDLAVFPRLIYLN 272

  Fly   480 HKIETIDL------------------AMNQISSLSRQGLFN-LTKLRHLNLSFNAISRIEVDTWE 525
            .....|.|                  :.:.:|:.||....: |::|.:|:||:|.|..:.....|
Mouse   273 VSNNLIQLPAGLPRGSEDLHAPSEGWSASPLSNPSRNASTHPLSQLLNLDLSYNEIELVPASFLE 337

  Fly   526 FTQSLEVLDLSNNAINEFKPQHLDCLHRLKTLNLAHNRLQYLQENTFDCVKNLEELNLRRNRLSW 590
            ...||..|:||.|.:..|:.:.:|.|..|..|:|:||.|:.|:..| ..:.:|:.|.|:.|.|
Mouse   338 HLTSLRFLNLSRNCLRSFEARQVDSLPCLVLLDLSHNVLEALELGT-KVLGSLQTLLLQDNAL-- 399

  Fly   591 IIEDQSAAAPFKGLRKLRRLDLHGNNLKQISTKA---------MSGLNNLEILNLGSNALASIQV 646
               .:.....|..|..|:||:|.||.:......|         .||:..|.:||:..|::..::.
Mouse   400 ---QELPPYTFASLASLQRLNLQGNQVSPCGGPAEPGPPGCVDFSGIPTLHVLNMAGNSMGMLRA 461

  Fly   647 NAFEH 651
            .:|.|
Mouse   462 GSFLH 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbk	NP_611091.2	LRR	<293..642	CDD:443914	115/424 (27%)
		leucine-rich repeat	293..316	CDD:275380	6/22 (27%)
		leucine-rich repeat	317..338	CDD:275380	5/22 (23%)
		leucine-rich repeat	339..362	CDD:275380	9/25 (36%)
		leucine-rich repeat	363..386	CDD:275380	11/33 (33%)
		leucine-rich repeat	387..410	CDD:275380	6/36 (17%)
		leucine-rich repeat	411..434	CDD:275380	10/22 (45%)
		leucine-rich repeat	435..457	CDD:275380	6/34 (18%)
		leucine-rich repeat	458..481	CDD:275380	8/27 (30%)
		leucine-rich repeat	482..505	CDD:275380	6/41 (15%)
		leucine-rich repeat	506..529	CDD:275380	7/22 (32%)
		leucine-rich repeat	530..553	CDD:275380	8/22 (36%)
		leucine-rich repeat	554..577	CDD:275380	8/22 (36%)
		leucine-rich repeat	578..604	CDD:275380	6/25 (24%)
		leucine-rich repeat	607..630	CDD:275380	9/31 (29%)
		leucine-rich repeat	631..652	CDD:275380	6/21 (29%)
		LRRCT	665..712	CDD:214507
		Ig_3	717..816	CDD:464046
		Ig	835..924	CDD:472250
		Ig strand B	851..855	CDD:409353
		Ig strand C	864..868	CDD:409353
		Ig strand E	890..894	CDD:409353
		Ig strand F	904..909	CDD:409353
		Ig strand G	917..920	CDD:409353
		Ig_3	927..1013	CDD:464046
Lrrc32	NP_001106850.1	PPP1R42	37..278	CDD:455733	71/254 (28%)
		LRR 1. /evidence=ECO:0000255	49..72		6/22 (27%)
		leucine-rich repeat	55..75	CDD:275380	5/19 (26%)
		LRR 2. /evidence=ECO:0000255	73..96		4/22 (18%)
		leucine-rich repeat	76..99	CDD:275380	5/22 (23%)
		LRR 3. /evidence=ECO:0000255	98..123		8/24 (33%)
		leucine-rich repeat	100..126	CDD:275380	9/25 (36%)
		LRR 4. /evidence=ECO:0000255	125..148		12/22 (55%)
		LRR	126..548	CDD:443914	96/361 (27%)
		leucine-rich repeat	127..151	CDD:275380	10/23 (43%)
		LRR 5. /evidence=ECO:0000255	149..172		4/22 (18%)
		leucine-rich repeat	152..175	CDD:275380	3/22 (14%)
		LRR 6. /evidence=ECO:0000255	174..196		3/21 (14%)
		leucine-rich repeat	176..199	CDD:275380	4/22 (18%)
		LRR 7. /evidence=ECO:0000255	197..220		11/25 (44%)
		leucine-rich repeat	200..220	CDD:275380	10/22 (45%)
		leucine-rich repeat	221..245	CDD:275380	5/23 (22%)
		LRR 8. /evidence=ECO:0000255	222..241		3/18 (17%)
		LRR 9. /evidence=ECO:0000255	243..267		9/34 (26%)
		leucine-rich repeat	246..267	CDD:275380	8/31 (26%)
		LRR 10. /evidence=ECO:0000255	269..287		3/17 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	291..311		3/19 (16%)
		LRR 11. /evidence=ECO:0000255	315..338		7/22 (32%)
		leucine-rich repeat	318..341	CDD:275380	7/22 (32%)
		LRR 12. /evidence=ECO:0000255	340..362		7/21 (33%)
		leucine-rich repeat	342..365	CDD:275380	8/22 (36%)
		LRR 13. /evidence=ECO:0000255	363..386		9/23 (39%)
		leucine-rich repeat	366..388	CDD:275380	8/22 (36%)
		LRR 14. /evidence=ECO:0000255	387..409		6/26 (23%)
		leucine-rich repeat	389..412	CDD:275380	7/27 (26%)
		LRR 15. /evidence=ECO:0000255	411..433		7/21 (33%)
		leucine-rich repeat	413..445	CDD:275380	9/31 (29%)
		LRR 16. /evidence=ECO:0000255	443..466		5/22 (23%)
		leucine-rich repeat	446..467	CDD:275380	6/21 (29%)
		LRR 17. /evidence=ECO:0000255	468..489
		leucine-rich repeat	469..493	CDD:275380
		LRR 18. /evidence=ECO:0000255	491..514
		leucine-rich repeat	494..516	CDD:275380
		LRR 19. /evidence=ECO:0000255	515..539
		leucine-rich repeat	517..538	CDD:275380
		leucine-rich repeat	539..560	CDD:275380
		LRR 20. /evidence=ECO:0000255	541..559
		LRR 21. /evidence=ECO:0000255	561..584
		leucine-rich repeat	564..576	CDD:275378