Protein Alignment lbk and Con

DIOPT Version :10

• Sequence 1: NP_611091.2
• Gene: lbk / 36788
• FlyBaseID: FBgn0034083
• Length: 1252
• Species: Drosophila melanogaster
• Sequence 2: NP_523930.3
• Gene: Con / 38590
• FlyBaseID: FBgn0005775
• Length: 691
• Species: Drosophila melanogaster
• Alignment Length: 682
• Identity: 155/682 - (22%)
• Similarity: 242/682 - (35%)
• Gaps: 241/682 - (35%)

  Fly    90 LITYMLLITAATICQSAAQSPSSSNGNGVGGSGSTGGSPLSALLKSGGASYNQQLPQQQLFAMLT 154
            |:..:|||.|..:..:..::.......|.|.|        |.:|.|..:|.|..
  Fly    21 LLLSLLLIGACLVTPTEGRAKDDRRTRGRGSS--------SGVLSSSSSSSNNM----------- 66

  Fly   155 RNGGGSSGPRSSGGNRGY--TSARQHFMALSEDYSDADVDEEDMAALHYPLSASHPPAGVQGSSS 217
            .||..|....::|.:.||  ||:                                       |:.
  Fly    67 NNGYYSGSSSTAGSSSGYVFTSS---------------------------------------SAV 92

  Fly   218 SSGISIQSGSLETNGFVADDGGQYEHAQKALEAAAAAAKASNKYNIDCPKDCKCLNVLFDCDKLH 282
            :||.:..||.:::.||..                         ...|....|.|..     |:.|
  Fly    93 NSGSTGYSGPMDSTGFCT-------------------------RRRDMKLMCYCTP-----DENH 127

  Fly   283 LERVPVLPS----YVQTLHLANNKLNDTTVLEIRNLLNLTKVSLKRNLLEVIPKFIGLSGLKHLV 343
               |||..:    :.:.||     .||||         .|:...::.|.|:  ||         |
  Fly   128 ---VPVQKAECWVFSEGLH-----QNDTT---------WTRFYQQKRLREL--KF---------V 164

  Fly   344 LANNHITSISSESLAALPLLRTLDLSRNKLHTIELNSFPKSNNLVHLILSFNEITNVNEHSFATL 408
            :.||          |.|..:.|:.:...|             ||..:::.::::..|..::||.|
  Fly   165 IQNN----------ARLDYIPTMIIEPLK-------------NLSSIVIEYSQVEIVKSYAFANL 206

  Fly   409 NNLTDLELSNNRLSTLPIRVFKNLNQLKKLALNFNQL-EINWSTFRGLESMKNLQLKSNKIRALQ 472
            ..|..:.|:||.:..|....|.|..:|::|.|..||: |::...||.|...:.|.|.:|.|..|.
  Fly   207 PFLERIILNNNHIMALDQDAFANHIRLRELNLEHNQIFEMDRYAFRNLPLCERLFLNNNNISTLH 271

  Fly   473 DGVFYVMHKIETIDLAMNQISSLSRQ-----GLFNLTKLRHLNLSFNAISRIEVDTWEFTQSLEV 532
            :|:|..|.::..::||.|||:.|:.:     |..|:.||...||:|.. ..:..:.|    ||..
  Fly   272 EGLFADMARLTFLNLAHNQINVLTSEIFRGLGNLNVLKLTRNNLNFIG-DTVFAELW----SLSE 331

  Fly   533 LDLSNNAINEFKPQHLDCLHRLKTLNLAHNRLQYLQENTFDCVKNLEELNLRRNRLSWIIEDQSA 597
            |:|.:|.|.....:.||.|:.||||||                         ||.|
  Fly   332 LELDDNRIERISERALDGLNTLKTLNL-------------------------RNNL--------- 362

  Fly   598 AAPFKGLRKLRRLDLHGNNLKQISTKAMSGLNNLEILNLGSNALASIQVNAFEHML-----RLNK 657
                               ||:|....:.|...|..:|:.:|.|.::....|:.::     ..::
  Fly   363 -------------------LKKIDNGLLRGTPALLSINVQANKLETLTFYTFQPIMDNLVNSTSE 408

  Fly   658 LVFKSLNFICDCDLVWFQQWLKNRFPQQAEHAVCGYPEHLLDRHLKSLSSSE-LVC-VDSPKPR- 719
            |:.....|||||.|.|..: ||||                 .|||:...|.| |.| :..||..
  Fly   409 LLVSDNKFICDCRLQWIFE-LKNR-----------------TRHLQLRDSLEDLHCTLQEPKLSH 455

  Fly   720 -VEQEPDDMLAV-NAANITLECIASSPTAASL 749
             |:..|..:|.| |....|    |....:||:
  Fly   456 FVDPVPPTILDVLNIGGFT----AIGSNSASM 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbk	NP_611091.2	LRR	<293..642	CDD:443914	87/354 (25%)
		leucine-rich repeat	293..316	CDD:275380	6/22 (27%)
		leucine-rich repeat	317..338	CDD:275380	5/20 (25%)
		leucine-rich repeat	339..362	CDD:275380	5/22 (23%)
		leucine-rich repeat	363..386	CDD:275380	2/22 (9%)
		leucine-rich repeat	387..410	CDD:275380	5/22 (23%)
		leucine-rich repeat	411..434	CDD:275380	7/22 (32%)
		leucine-rich repeat	435..457	CDD:275380	9/22 (41%)
		leucine-rich repeat	458..481	CDD:275380	8/22 (36%)
		leucine-rich repeat	482..505	CDD:275380	8/27 (30%)
		leucine-rich repeat	506..529	CDD:275380	5/22 (23%)
		leucine-rich repeat	530..553	CDD:275380	8/22 (36%)
		leucine-rich repeat	554..577	CDD:275380	6/22 (27%)
		leucine-rich repeat	578..604	CDD:275380	3/25 (12%)
		leucine-rich repeat	607..630	CDD:275380	4/22 (18%)
		leucine-rich repeat	631..652	CDD:275380	5/20 (25%)
		LRRCT	665..712	CDD:214507	17/47 (36%)
		Ig_3	717..816	CDD:464046	10/36 (28%)
		Ig	835..924	CDD:472250
		Ig strand B	851..855	CDD:409353
		Ig strand C	864..868	CDD:409353
		Ig strand E	890..894	CDD:409353
		Ig strand F	904..909	CDD:409353
		Ig strand G	917..920	CDD:409353
		Ig_3	927..1013	CDD:464046
Con	NP_523930.3	LRR	<157..459	CDD:443914	104/411 (25%)
		leucine-rich repeat	185..208	CDD:275380	5/22 (23%)
		leucine-rich repeat	209..232	CDD:275380	7/22 (32%)
		leucine-rich repeat	233..256	CDD:275380	9/22 (41%)
		leucine-rich repeat	257..280	CDD:275380	8/22 (36%)
		leucine-rich repeat	281..304	CDD:275380	6/22 (27%)
		leucine-rich repeat	305..328	CDD:275380	7/27 (26%)
		leucine-rich repeat	329..352	CDD:275380	8/22 (36%)
		leucine-rich repeat	353..376	CDD:275380	13/75 (17%)