Protein Alignment lbk and Cpn2

DIOPT Version :10

• Sequence 1: NP_611091.2
• Gene: lbk / 36788
• FlyBaseID: FBgn0034083
• Length: 1252
• Species: Drosophila melanogaster
• Sequence 2: NP_001100555.2
• Gene: Cpn2 / 303861
• RGDID: 1305170
• Length: 565
• Species: Rattus norvegicus
• Alignment Length: 562
• Identity: 146/562 - (25%)
• Similarity: 250/562 - (44%)
• Gaps: 60/562 - (10%)

  Fly   265 CPKDCKCLNVLFDCDKLHLERVPV-LPSYVQTLHLANNKLNDTTVLEIRNLLNLTKVSLKRNLLE 328
            ||..|.|.:....|....|..:|: :||:|          .|...:|    .:.|.|..:
  Rat    45 CPVGCDCFDRKIFCSDEQLAAIPLDIPSHV----------TDIVFVE----TSFTTVGTR----- 90

  Fly   329 VIPKFIGLSGLKHLVLANNHITSISSESLAALPLLRTLDLSRNKLHTIELNSFPKSNNLVHLILS 393
               .|.|...|..:|..|..:..:..::...||.|..|:::.:....:..|.|...::|..|.|.
  Rat    91 ---AFSGSPNLTKVVFLNTRVHHLEPDAFGGLPRLEDLEVTGSPFSNLSANIFSNLSSLGKLTLD 152

  Fly   394 FNEITNVNEHSFATLNNLTDLELSNNRLSTLPIRVFKNLNQLKKLALNFNQL-EINWSTFRGLES 457
            ||.:..:.|..|..::.|..|:|..|:|.|||.|:|::|..|:.|.|..|.| ::....|:.|.|
  Rat   153 FNRLAALPEDLFHHMDTLESLQLQGNQLQTLPGRLFQSLRYLRTLNLAQNLLTQLPKGMFQSLSS 217

  Fly   458 MKNLQLKSNKIRALQDGVFYVMHKIETIDLAMNQISSLSRQGLFNLTKLRHLNLSFNAISRIEVD 522
            ::.|:|..|....|.:||...:..::.:.|..|.|:.||.....:|..|..|.|..||||.:.|.
  Rat   218 LQILKLSDNMFARLPEGVLSNLGSLQELFLDSNAITELSPHLFSHLLSLEKLWLQHNAISLLPVS 282

  Fly   523 TWEFTQSLEVLDLSNNAINEFKPQHL-----DCLHRLKTLNLAHNRLQYLQENTFDCVKNLEELN 582
            .:...::|..|:|.:||:... |..|     ..||    |:|::|:|:.:.|.:|..::.|..|.
  Rat   283 AFSSLRNLTFLNLKDNALRTL-PAGLFTHNPGLLH----LSLSYNQLETVPEGSFANLRKLASLT 342

  Fly   583 LRRNRLSWIIEDQSAAAPFKGLRKLRRLDLHGNNLKQISTKAMSGLNNLEILNLGSNALASIQVN 647
            |..|.::.:.|:     .|:.|.:|.:|.|..|||..:.......|:.|::|:|..|.|..:...
  Rat   343 LSHNAITHLPEN-----VFRNLEQLVKLSLDSNNLTVLHPTLFHNLSKLQLLDLSRNQLTMLPGG 402

  Fly   648 AFEHMLRLNKLVFKSLNFICDCDLVWFQQWLK---NRFPQQAEHAVCGYPEHLLDRHLKSLSSSE 709
            .|:....|..|......:.|||.|.:...||:   :|...  .|..|..|.:|..:.:.:|...:
  Rat   403 IFDTNYDLFNLALLGNPWQCDCRLSYLTSWLRLYNDRIFN--THTFCAGPAYLKGQLVPNLKQEQ 465

  Fly   710 LVCVDSPKP--RVEQEPDDM--LAVNAANITLECIASSPTAASLAAADELKIKWRH---DNQHVQ 767
            |||..:|..  ..::||...  |||.......:||..:|....|.|.:|.:.:|.:   .::...
  Rat   466 LVCPGNPGQLGLDDREPAGSWDLAVEGRAAHRQCIYGNPEGTVLLACEEAQCRWLNIQLSSREGS 530

  Fly   768 ERPAVHDGASTETQIRHDLSTNQTSIYGYLRLT-NVTYESAG 808
            :..|:...:|.|.::|        |..|.:|:| ::..::||
  Rat   531 DVTAMAYNSSQEWELR--------STCGSVRVTVSIEAQAAG 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbk	NP_611091.2	LRR	<293..642	CDD:443914	95/354 (27%)
		leucine-rich repeat	293..316	CDD:275380	3/22 (14%)
		leucine-rich repeat	317..338	CDD:275380	4/20 (20%)
		leucine-rich repeat	339..362	CDD:275380	4/22 (18%)
		leucine-rich repeat	363..386	CDD:275380	4/22 (18%)
		leucine-rich repeat	387..410	CDD:275380	7/22 (32%)
		leucine-rich repeat	411..434	CDD:275380	11/22 (50%)
		leucine-rich repeat	435..457	CDD:275380	7/22 (32%)
		leucine-rich repeat	458..481	CDD:275380	6/22 (27%)
		leucine-rich repeat	482..505	CDD:275380	6/22 (27%)
		leucine-rich repeat	506..529	CDD:275380	8/22 (36%)
		leucine-rich repeat	530..553	CDD:275380	8/27 (30%)
		leucine-rich repeat	554..577	CDD:275380	6/22 (27%)
		leucine-rich repeat	578..604	CDD:275380	6/25 (24%)
		leucine-rich repeat	607..630	CDD:275380	7/22 (32%)
		leucine-rich repeat	631..652	CDD:275380	6/20 (30%)
		LRRCT	665..712	CDD:214507	13/49 (27%)
		Ig_3	717..816	CDD:464046	22/100 (22%)
		Ig	835..924	CDD:472250
		Ig strand B	851..855	CDD:409353
		Ig strand C	864..868	CDD:409353
		Ig strand E	890..894	CDD:409353
		Ig strand F	904..909	CDD:409353
		Ig strand G	917..920	CDD:409353
		Ig_3	927..1013	CDD:464046
Cpn2	NP_001100555.2	LRRNT	44..75	CDD:214470	10/39 (26%)
		leucine-rich repeat	77..97	CDD:275380	5/31 (16%)
		LRR	118..418	CDD:443914	89/309 (29%)
		leucine-rich repeat	122..145	CDD:275380	4/22 (18%)
		leucine-rich repeat	146..169	CDD:275380	7/22 (32%)
		leucine-rich repeat	170..193	CDD:275380	11/22 (50%)
		leucine-rich repeat	194..217	CDD:275380	7/22 (32%)
		leucine-rich repeat	218..241	CDD:275380	6/22 (27%)
		leucine-rich repeat	242..265	CDD:275380	6/22 (27%)
		leucine-rich repeat	266..289	CDD:275380	8/22 (36%)
		leucine-rich repeat	290..313	CDD:275380	7/23 (30%)
		leucine-rich repeat	314..337	CDD:275380	8/26 (31%)
		leucine-rich repeat	338..361	CDD:275380	7/27 (26%)
		leucine-rich repeat	362..383	CDD:275380	6/20 (30%)
		leucine-rich repeat	386..405	CDD:275380	5/18 (28%)
		PCC	390..>499	CDD:188093	27/110 (25%)