Protein Alignment lbk and Lrrtm3

DIOPT Version :10

• Sequence 1: NP_611091.2
• Gene: lbk / 36788
• FlyBaseID: FBgn0034083
• Length: 1252
• Species: Drosophila melanogaster
• Sequence 2: NP_848793.1
• Gene: Lrrtm3 / 216028
• MGIID: 2389177
• Length: 582
• Species: Mus musculus
• Alignment Length: 328
• Identity: 68/328 - (20%)
• Similarity: 101/328 - (30%)
• Gaps: 98/328 - (29%)

  Fly   455 KSQILQSCANVSPRGIFVCGTNSSNVGLTVTVRTEKGVGASLEAGALVLADQGVCCIDEFDKMSG 519
            |||.|.:.:|.||..:.....|..|            ..||:|.||.:|:...       :..|.
Mouse   347 KSQSLHTSSNGSPHPVKKVQKNFKN------------NYASVECGAKILSANN-------EAKST 392

  Fly   520 HSGLLEVMEQRSVSVAKAGVICTVPARTTVLAAANPAGGHYNKAKTVSENLKLHPALLSRF---- 580
            .:.|:|.|:                     |...||..........:.|.:::....::.|
Mouse   393 SAILMENMD---------------------LYMLNPCSTKIWFVIELCEPIQVKQLDIANFELFS 436

  Fly   581 ----DLVFILLDR--------------SNERT------DNLLTAHIQKVHGLAKAGSSHLQPQPS 621
                |.:..:.||              .:|||      |..|.|...||..|:..||.|..|...
Mouse   437 STPRDFLVSISDRYPTNKWIKLGTFHARDERTVQSFPLDEQLYAKYVKVELLSHFGSEHFCPLSL 501

  Fly   622 HPFF--------DASGHCSYEEEGEPPLEERLRLAPGEQMDLLPPEIVQKYIGYARKNVQPKLTA 678
            ...|        |......|..|....|:|.....||    .||.|      ..|.||:....|.
Mouse   502 IRVFGTSMVEEYDEIADSQYTSERAEYLDEDYDYPPG----YLPSE------DKASKNLLGSATN 556

  Fly   679 KAAEELREFFVELRRAHNHMDMIPVTTRQLEGLI-----RLTQARAKIDLSPEATVA---HVRDV 735
            .....:......:......::    ...:|||.:     .:|||..:..|:|:.|..   |..||
Mouse   557 AILNMVNNIAANVLGGKPELE----DGAELEGNVSSGTENVTQASTETTLTPDPTPTEQPHTLDV 617

  Fly   736 LAI 738
            |.:
Mouse   618 LEL 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbk	NP_611091.2	LRR	<293..642	CDD:443914	44/222 (20%)
		leucine-rich repeat	293..316	CDD:275380
		leucine-rich repeat	317..338	CDD:275380
		leucine-rich repeat	339..362	CDD:275380
		leucine-rich repeat	363..386	CDD:275380
		leucine-rich repeat	387..410	CDD:275380
		leucine-rich repeat	411..434	CDD:275380
		leucine-rich repeat	435..457	CDD:275380	1/1 (100%)
		leucine-rich repeat	458..481	CDD:275380	6/22 (27%)
		leucine-rich repeat	482..505	CDD:275380	6/22 (27%)
		leucine-rich repeat	506..529	CDD:275380	4/22 (18%)
		leucine-rich repeat	530..553	CDD:275380	1/22 (5%)
		leucine-rich repeat	554..577	CDD:275380	3/22 (14%)
		leucine-rich repeat	578..604	CDD:275380	10/53 (19%)
		leucine-rich repeat	607..630	CDD:275380	7/30 (23%)
		leucine-rich repeat	631..652	CDD:275380	6/20 (30%)
		LRRCT	665..712	CDD:214507	7/46 (15%)
		Ig_3	717..816	CDD:464046	8/25 (32%)
		Ig	835..924	CDD:472250
		Ig strand B	851..855	CDD:409353
		Ig strand C	864..868	CDD:409353
		Ig strand E	890..894	CDD:409353
		Ig strand F	904..909	CDD:409353
		Ig strand G	917..920	CDD:409353
		Ig_3	927..1013	CDD:464046
Lrrtm3	NP_848793.1	LRRNT	33..61	CDD:214470
		LRR	59..339	CDD:443914
		LRR 1	63..83
		leucine-rich repeat	66..86	CDD:275380
		LRR 2	86..107
		leucine-rich repeat	87..110	CDD:275380
		LRR 3	110..131
		leucine-rich repeat	111..134	CDD:275380
		LRR 4	134..155
		leucine-rich repeat	135..158	CDD:275380
		LRR 5	158..179
		leucine-rich repeat	159..182	CDD:275380
		LRR 6	182..203
		leucine-rich repeat	183..206	CDD:275380
		LRR 7	206..226
		leucine-rich repeat	207..230	CDD:275380
		LRR 8	230..251
		leucine-rich repeat	231..254	CDD:275380
		LRR 9	254..275
		leucine-rich repeat	255..279	CDD:275380
		LRR 10	279..300
		leucine-rich repeat	280..300	CDD:275380
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	378..410		10/59 (17%)