Protein Alignment lbk and gp5

DIOPT Version :10

• Sequence 1: NP_611091.2
• Gene: lbk / 36788
• FlyBaseID: FBgn0034083
• Length: 1252
• Species: Drosophila melanogaster
• Sequence 2: XP_031758900.1
• Gene: gp5 / 116411101
• XenbaseID: XB-GENE-17346925
• Length: 615
• Species: Xenopus tropicalis
• Alignment Length: 535
• Identity: 145/535 - (27%)
• Similarity: 243/535 - (45%)
• Gaps: 54/535 - (10%)

  Fly   265 CPKDCKC-LNVLFDCDKLHLERVP--VLPSYVQTLHLANNKLNDTTVLEIRNLLNLTKVSLKRNL 326
            ||..|.| |.....|....::.:.  :|||....:|:......:.|.....|:....::.|:.|.
 Frog    20 CPTLCNCDLKDAIICRGTSIKDIGSLLLPSNFTYIHIMETLATEITDKSFGNMPVTLRLRLEANH 84

  Fly   327 LEVIPK--FIGLSGLKHLVLANNHITSISSESLAALPLLRTLDLSRNKLHTIELNSFPKSNNLVH 389
            |..|.:  |.....||.|.|.:|.:.::.:....:|..|..|.|.:|.|.::..|.|....:|..
 Frog    85 LTSITRNAFKSFPHLKSLKLTDNKLKTLPAGMFDSLISLEQLFLDKNCLSSLHPNLFCCLQHLEE 149

  Fly   390 LILSFNEITNVNEHSFATLNNLTDLELSNNRLSTLPIRVFKNLNQLKKLALNFNQL-EINWSTFR 453
            |||:.|::|::.:.....|..|..|.||.|::|.||:.:|.:|.:||||.|..||| .|..|.|.
 Frog   150 LILNRNQLTSLPDELLKNLTKLISLNLSRNKISHLPMSIFSSLTKLKKLFLYDNQLVTITSSAFN 214

  Fly   454 GLESMKNLQLKSNKIRALQDGVFYVMHKIETIDLAMNQISSLSRQGLF-NLTKLRHLNLSFNAIS 517
            .|..:.:|.|.||.|:.:....||.:.|::::.|:.|::..|. .||| :|.:|..|.|..|.:.
 Frog   215 KLGELLDLALYSNSIQFVAQDAFYHLPKLQSLKLSKNKLQLLP-YGLFLHLPQLSTLTLYDNPLK 278

  Fly   518 RIEVDTWEFTQSLEVLDLSNNAINEFKPQHLDC-LHRLKTLNLAHN-RLQYLQENTFDCVKNLEE 580
            .:....:...::|..|.|.|..:... |..:.| |..|:.|.|..| :|..|.:..|..:.||.|
 Frog   279 ELPDVLFGKMENLTSLWLYNTHLTTI-PNFVFCNLTNLQLLVLTRNAQLDSLPKEAFSGLNNLLE 342

  Fly   581 LNLRRNRLSWIIEDQSAAAPFKGLRKLRRLDLHGNNLKQISTKAMSGLNNLEILNLGSNALASIQ 645
            |:|..|.||.|..|     .|:.|:.|.:|.|:.||||.:|......|..|:||:|.::.|.::.
 Frog   343 LSLHSNNLSSIDND-----VFQNLQLLEKLSLYSNNLKVLSENMFYNLTKLQILHLNNSNLHTLP 402

  Fly   646 VNAFEHMLRLNKLVFKSLNFICDCDLVWFQQWLKNRFPQQAEH-------AVCGYPEHLLDRHLK 703
            ...|:.:..|..:...|..:.|.|:|..|:.|.     ||.::       .||..|..|  .::.
 Frog   403 GQIFQELPSLQMVYLHSNPWACYCELTDFKMWF-----QQNQNKVYNPMSLVCDTPFTL--SNIS 460

  Fly   704 SLSSSELVCVDSPKPRVEQEPDDMLAVNAANITLECIASSPTAASLAAADELKIKWRHDN---QH 765
            .|::.|.:|               ....|....|:..|:|.|.:::.:.      :.::|   .:
 Frog   461 VLAAGESIC---------------HYTTAKQNNLDTTANSQTTSNIQST------YSYNNIEFTN 504

  Fly   766 VQERPAVHDGASTET 780
            |:.:|..:..:.|.|
 Frog   505 VKTQPISYTTSPTAT 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbk	NP_611091.2	LRR	<293..642	CDD:443914	108/354 (31%)
		leucine-rich repeat	293..316	CDD:275380	3/22 (14%)
		leucine-rich repeat	317..338	CDD:275380	5/22 (23%)
		leucine-rich repeat	339..362	CDD:275380	6/22 (27%)
		leucine-rich repeat	363..386	CDD:275380	7/22 (32%)
		leucine-rich repeat	387..410	CDD:275380	7/22 (32%)
		leucine-rich repeat	411..434	CDD:275380	10/22 (45%)
		leucine-rich repeat	435..457	CDD:275380	12/22 (55%)
		leucine-rich repeat	458..481	CDD:275380	7/22 (32%)
		leucine-rich repeat	482..505	CDD:275380	7/23 (30%)
		leucine-rich repeat	506..529	CDD:275380	4/22 (18%)
		leucine-rich repeat	530..553	CDD:275380	7/23 (30%)
		leucine-rich repeat	554..577	CDD:275380	7/23 (30%)
		leucine-rich repeat	578..604	CDD:275380	10/25 (40%)
		leucine-rich repeat	607..630	CDD:275380	9/22 (41%)
		leucine-rich repeat	631..652	CDD:275380	6/20 (30%)
		LRRCT	665..712	CDD:214507	13/53 (25%)
		Ig_3	717..816	CDD:464046	10/67 (15%)
		Ig	835..924	CDD:472250
		Ig strand B	851..855	CDD:409353
		Ig strand C	864..868	CDD:409353
		Ig strand E	890..894	CDD:409353
		Ig strand F	904..909	CDD:409353
		Ig strand G	917..920	CDD:409353
		Ig_3	927..1013	CDD:464046
gp5	XP_031758900.1	LRR	75..374	CDD:443914	96/305 (31%)
		leucine-rich repeat	75..98	CDD:275380	5/22 (23%)
		leucine-rich repeat	99..122	CDD:275380	6/22 (27%)
		leucine-rich repeat	123..146	CDD:275380	7/22 (32%)
		leucine-rich repeat	147..170	CDD:275380	7/22 (32%)
		leucine-rich repeat	171..194	CDD:275380	10/22 (45%)
		leucine-rich repeat	195..218	CDD:275380	12/22 (55%)
		leucine-rich repeat	219..242	CDD:275380	7/22 (32%)
		leucine-rich repeat	243..266	CDD:275380	7/23 (30%)
		leucine-rich repeat	267..290	CDD:275380	4/22 (18%)
		leucine-rich repeat	291..314	CDD:275380	7/23 (30%)
		leucine-rich repeat	315..337	CDD:275380	7/21 (33%)
		leucine-rich repeat	340..363	CDD:275380	11/27 (41%)
		LRR_8	364..421	CDD:404697	17/56 (30%)
		leucine-rich repeat	364..387	CDD:275380	9/22 (41%)
		leucine-rich repeat	388..409	CDD:275380	6/20 (30%)
		PCC	393..>483	CDD:188093	21/111 (19%)