Protein Alignment lbk and rtn4rl2

DIOPT Version :10

• Sequence 1: NP_611091.2
• Gene: lbk / 36788
• FlyBaseID: FBgn0034083
• Length: 1252
• Species: Drosophila melanogaster
• Sequence 2: XP_017951401.1
• Gene: rtn4rl2 / 100498486
• XenbaseID: XB-GENE-6036061
• Length: 396
• Species: Xenopus tropicalis
• Alignment Length: 510
• Identity: 105/510 - (20%)
• Similarity: 157/510 - (30%)
• Gaps: 200/510 - (39%)

  Fly   265 CPKDCKCL--NVLFDCDKLHLERVPV-LPSYVQTLHLANNKLNDTTVLEIRNLLNLTKVSLKRNL 326
            ||..|.|.  .....|...:|.|||. |||..|
 Frog    38 CPTLCTCYPSPPTASCQSHNLSRVPFPLPSSAQ-------------------------------- 70

  Fly   327 LEVIPKFIGLSGLKHLVLANNHITSISSESLAALPLLRTLDLSRNKLHTIELNSFPKSNNLVHLI 391
                          .|.|.||||:.|.....:.|..:                          |.
 Frog    71 --------------RLFLQNNHISEIGPGLFSPLTSV--------------------------LW 95

  Fly   392 LSFNEITNVNEHSFATLNNLTDLELSNN-RLSTLPIRVFKNLNQLKKLAL---NFNQLEINWSTF 452
            |..|.|:.::..:|..|.||.:|:|.|| :...|....|:.|..|:.|.|   :.|:|..  ..|
 Frog    96 LFSNHISILHPGAFNGLENLEELDLGNNPKFPILQSDTFEGLKSLRSLHLYHCHINRLPS--GLF 158

  Fly   453 RGLESMKNLQLKSNKIRALQDGVFYVMHKIETIDLAMNQISSLSRQGLFNLTKLRHLNLSFNAIS 517
            |||.|::.|.|::|::..|.||:|                     :.|||||:
 Frog   159 RGLYSLRYLYLQNNRLTVLPDGLF---------------------RDLFNLTQ------------ 190

  Fly   518 RIEVDTWEFTQSLEVLDLSNNAINEFKPQHLDCLHRLKTLNLAHNRLQYLQENTFDCVKNLEELN 582
                                                   |.|..|.||.|...:|..:.||:.|.
 Frog   191 ---------------------------------------LFLYGNLLQSLPAESFFGLSNLDRLL 216

  Fly   583 LRRNRLSWIIEDQSAAAPFKGLRKLRRLDLHGNNLKQISTKAMSGLNNLEILNLGSNALASIQVN 647
            |..|:|:.:     :...|:||:.|..|.|..|:|..:....:..|.:|:.|.|..|.
 Frog   217 LHSNQLAVV-----SPGAFRGLKSLTMLYLFNNSLPTLPGDCLQPLTSLQFLRLNENP------- 269

  Fly   648 AFEHMLRLNKLVFKSLNFICDCDLVWFQQWLKNRFPQQAEHAVCGYPEHLLDRHLKSLSSSEL-V 711
                             :.|||......:|..:.....:....|..|..|..|.|:.|...:| .
 Frog   270 -----------------WHCDCSCRSLWRWFHSTPGVSSSPVTCNSPPPLKGRDLRFLVERDLRF 317

  Fly   712 CVDSPKPR-----------------VEQEPDDMLAVNAANITLECIASSPTAASL 749
            |..:..||                 ::.:|..:|.......|:|....|..:||:
 Frog   318 CTSNISPRNGNLSDLAFPHKPSSFYIQGDPGAVLEAGEWENTIEEGGGSGQSASI 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbk	NP_611091.2	LRR	<293..642	CDD:443914	72/352 (20%)
		leucine-rich repeat	293..316	CDD:275380	1/22 (5%)
		leucine-rich repeat	317..338	CDD:275380	0/20 (0%)
		leucine-rich repeat	339..362	CDD:275380	8/22 (36%)
		leucine-rich repeat	363..386	CDD:275380	0/22 (0%)
		leucine-rich repeat	387..410	CDD:275380	6/22 (27%)
		leucine-rich repeat	411..434	CDD:275380	8/23 (35%)
		leucine-rich repeat	435..457	CDD:275380	9/24 (38%)
		leucine-rich repeat	458..481	CDD:275380	7/22 (32%)
		leucine-rich repeat	482..505	CDD:275380	4/22 (18%)
		leucine-rich repeat	506..529	CDD:275380	0/22 (0%)
		leucine-rich repeat	530..553	CDD:275380	0/22 (0%)
		leucine-rich repeat	554..577	CDD:275380	7/22 (32%)
		leucine-rich repeat	578..604	CDD:275380	6/25 (24%)
		leucine-rich repeat	607..630	CDD:275380	6/22 (27%)
		leucine-rich repeat	631..652	CDD:275380	4/20 (20%)
		LRRCT	665..712	CDD:214507	11/47 (23%)
		Ig_3	717..816	CDD:464046	9/50 (18%)
		Ig	835..924	CDD:472250
		Ig strand B	851..855	CDD:409353
		Ig strand C	864..868	CDD:409353
		Ig strand E	890..894	CDD:409353
		Ig strand F	904..909	CDD:409353
		Ig strand G	917..920	CDD:409353
		Ig_3	927..1013	CDD:464046
rtn4rl2	XP_017951401.1	leucine-rich repeat	69..92	CDD:275380	9/68 (13%)
		LRR	<70..>286	CDD:443914	76/390 (19%)
		leucine-rich repeat	93..114	CDD:275380	6/46 (13%)
		leucine-rich repeat	115..139	CDD:275380	8/23 (35%)
		leucine-rich repeat	140..163	CDD:275380	9/24 (38%)
		leucine-rich repeat	164..187	CDD:275380	8/43 (19%)
		leucine-rich repeat	188..211	CDD:275380	9/73 (12%)
		leucine-rich repeat	212..235	CDD:275380	8/27 (30%)
		leucine-rich repeat	236..259	CDD:275380	6/22 (27%)
		LRRCT	268..310	CDD:214507	10/65 (15%)