Protein Alignment lbk and tlrs5

DIOPT Version :10

• Sequence 1: NP_611091.2
• Gene: lbk / 36788
• FlyBaseID: FBgn0034083
• Length: 1252
• Species: Drosophila melanogaster
• Sequence 2: XP_002937550.2
• Gene: tlrs5 / 100489423
• XenbaseID: XB-GENE-22201327
• Length: 653
• Species: Xenopus tropicalis
• Alignment Length: 563
• Identity: 146/563 - (25%)
• Similarity: 236/563 - (41%)
• Gaps: 158/563 - (28%)

  Fly   281 LHLERVPVLPSYVQTLHLANNKLNDTTVLE---IRNLLNLTKVSLKRNLLEVI---PKFIGLSGL 339
            ||.|....| |:::.|.|.:|.| |.:|||   .::|.:|.|:.|..|.:..:   |.|:.||.:
 Frog   121 LHPEAFEGL-SWLEVLLLDHNGL-DESVLESGMFKDLTSLKKLDLSFNNIRRVRPDPTFLKLSSI 183

  Fly   340 KHLVLANNHITSISSESLAALP--LLRTLDLSRNKLHTIELNSFPKSNNLVHLI----------- 391
            ..|:|..|.::.:..|.|..|.  .|:.||:|.|.|   :|:|.|...|..:.|
 Frog   184 SFLLLKFNKVSMLCGEDLQNLQGRRLQLLDMSSNPL---QLSSTPHCTNPFNNITLGTLDVSSMG 245

  Fly   392 --------------------------------LSFNEITNVNEHSFATLNN-------------- 410
                                            ..|:.:.:.|:.:|:.||:
 Frog   246 WNAEMVENFVRTISGTQVDYIKMRHTAGLGSGFGFHNLKDPNKDTFSGLNSSNVQILDLSNGFIS 310

  Fly   411 ------------LTDLELSNNRLSTLPIRVFKNLNQLKKLALNFNQL-EINWSTFRGL--ESMKN 460
                        |..|:||:|:::.:....|..|.:|..|.|:.|.| |:..|:|:||  .|:|.
 Frog   311 HLVPQLFSAFPKLLSLDLSSNQINRMSSGAFSGLGELVSLNLSGNLLGELMGSSFQGLGATSLKT 375

  Fly   461 LQLKSNKIRALQDGV---FYVMHKIETIDLAMNQISSLSRQGL-FNLTKLRHLNLSFNAISRIEV 521
            |.|.||.|.|:|.|.   |..:..:...|.|:|:|.....||: |.|.|...::..:|.||
 Frog   376 LDLSSNHIGAVQYGALDSFTALTSLNLRDNALNKIPPTKLQGVTFVLLKQNRISDIYNIIS---- 436

  Fly   522 DTWEFTQSLEVLDLSNNAINEFKP--QHLDCLHRLKTLNLAHNRLQY------------------ 566
                |.....:||||:|.:.:|:.  |.|: |..||.|:||.|.|..
 Frog   437 ----FCPHATILDLSSNRLTDFRSLWQILE-LQSLKYLSLASNSLYRCSLPHTSNITRTSGLVYL 496

  Fly   567 -LQENTF-------DC------VKNLEELNLRRNRLSWIIEDQSAAAPFKGLRKLRRLDLHGNNL 617
             |.:|..       :|      :.:|:.|||.||:||.|.:..     |:.|..|:.|||.||..
 Frog   497 DLSDNALGPVLKSGECGDIFMHLGSLKSLNLARNQLSNIPDTM-----FRSLSSLQTLDLSGNGF 556

  Fly   618 KQISTKAMSGLNNLEILNLGSNALASIQVNAFEHMLRLNKLVFKSLNFICDCDLVWFQQWLKNRF 682
            |:|.:...:||..|:.||||.:.|.::..:..:.:..|..:....:..:|||.|..|.:||:
 Frog   557 KEIQSNLFTGLTALKTLNLGKSNLVTLSSSVLDPLGSLESIDLSEVTLVCDCSLWDFWKWLE--- 618

  Fly   683 PQQAEHAVCGYPEHLLDRHLK-SLSSSELVCVDSPKPRVEQEP 724
                            |.::. ::...|::|: .|.||:.:.|
 Frog   619 ----------------DTNVTVNVGKQEVLCI-QPTPRIPEIP 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbk	NP_611091.2	LRR	<293..642	CDD:443914	125/466 (27%)
		leucine-rich repeat	293..316	CDD:275380	9/25 (36%)
		leucine-rich repeat	317..338	CDD:275380	7/23 (30%)
		leucine-rich repeat	339..362	CDD:275380	6/24 (25%)
		leucine-rich repeat	363..386	CDD:275380	9/22 (41%)
		leucine-rich repeat	387..410	CDD:275380	5/65 (8%)
		leucine-rich repeat	411..434	CDD:275380	7/22 (32%)
		leucine-rich repeat	435..457	CDD:275380	10/24 (42%)
		leucine-rich repeat	458..481	CDD:275380	10/25 (40%)
		leucine-rich repeat	482..505	CDD:275380	8/23 (35%)
		leucine-rich repeat	506..529	CDD:275380	4/22 (18%)
		leucine-rich repeat	530..553	CDD:275380	9/24 (38%)
		leucine-rich repeat	554..577	CDD:275380	10/54 (19%)
		leucine-rich repeat	578..604	CDD:275380	10/25 (40%)
		leucine-rich repeat	607..630	CDD:275380	10/22 (45%)
		leucine-rich repeat	631..652	CDD:275380	6/20 (30%)
		LRRCT	665..712	CDD:214507	9/47 (19%)
		Ig_3	717..816	CDD:464046	3/8 (38%)
		Ig	835..924	CDD:472250
		Ig strand B	851..855	CDD:409353
		Ig strand C	864..868	CDD:409353
		Ig strand E	890..894	CDD:409353
		Ig strand F	904..909	CDD:409353
		Ig strand G	917..920	CDD:409353
		Ig_3	927..1013	CDD:464046
tlrs5	XP_002937550.2	RNA1	<100..269	CDD:444072	39/152 (26%)
		LRR_8	106..168	CDD:404697	18/48 (38%)
		leucine-rich repeat	108..131	CDD:275380	4/10 (40%)
		leucine-rich repeat	132..157	CDD:275380	9/25 (36%)
		leucine-rich repeat	158..182	CDD:275380	7/23 (30%)
		leucine-rich repeat	183..208	CDD:275380	6/24 (25%)
		leucine-rich repeat	209..232	CDD:275380	10/25 (40%)
		LRR	291..632	CDD:443914	100/373 (27%)
		leucine-rich repeat	299..322	CDD:275380	0/22 (0%)
		leucine-rich repeat	323..346	CDD:275380	7/22 (32%)
		leucine-rich repeat	347..372	CDD:275380	10/24 (42%)
		leucine-rich repeat	373..396	CDD:275380	10/22 (45%)
		leucine-rich repeat	397..440	CDD:275380	13/50 (26%)
		leucine-rich repeat	418..431	CDD:275378	3/12 (25%)
		leucine-rich repeat	441..492	CDD:275380	16/51 (31%)
		leucine-rich repeat	493..521	CDD:275380	3/27 (11%)
		leucine-rich repeat	522..545	CDD:275380	11/27 (41%)
		leucine-rich repeat	546..569	CDD:275380	10/22 (45%)
		leucine-rich repeat	570..591	CDD:275380	6/20 (30%)