Protein Alignment lbk and lrrtm4

DIOPT Version :10

• Sequence 1: NP_611091.2
• Gene: lbk / 36788
• FlyBaseID: FBgn0034083
• Length: 1252
• Species: Drosophila melanogaster
• Sequence 2: XP_031755133.1
• Gene: lrrtm4 / 100485215
• XenbaseID: XB-GENE-949702
• Length: 622
• Species: Xenopus tropicalis
• Alignment Length: 499
• Identity: 111/499 - (22%)
• Similarity: 201/499 - (40%)
• Gaps: 136/499 - (27%)

  Fly   265 CPKDCKCLNVLFDCDKLHLERVPVLPSYVQTLHLANNKLNDTTVLEIRNLLNLTK-VSLKRNLLE 328
            |||:|:|...:..|:......:|                        :|:...:: :||:.|.::
 Frog    34 CPKNCRCDGKIVYCESHAFRDIP------------------------QNISGGSQGLSLRYNSIK 74

  Fly   329 VIP--KFIGLSGLKHLVLANNHITSISSESLAALPLLRTLDLSRNKLHTIELNSFPKSNNLVHLI 391
            ::.  :|.||:.|..|.|.:|:|:::..::...:..|:.|.||.||:..:..::|....||.:|.
 Frog    75 MLKSHQFSGLNQLVWLYLDHNYISTVDEDAFQGIRRLKELILSSNKISYLGNSTFHPVPNLRNLD 139

  Fly   392 LSFNEITNVNEHSFATLNNLTDLELSNNRLSTLPIRVFKNLNQLKKLALNFNQL-EINWSTFRGL 455
            ||:|::..:....|..|..|..|.|.:|.|.|:|:|||::...|..|.|.:|:| .::.:.|.||
 Frog   140 LSYNKLQTLQSEQFKGLRKLLILHLRSNSLKTVPVRVFQDCRNLDFLDLGYNRLRSLSRNAFAGL 204

  Fly   456 ESMKNLQLKSNKIRALQDGVFYVMHKIETIDLAMNQISSLSRQGLFNLTKLRHLNLSFNAISRIE 520
            ..:|.|.|:.|:...:....|..:..:.::.|..|:|.|:| |||
 Frog   205 LKLKELHLEHNQFSKVNFAHFPRLFNLRSLYLQWNKIRSIS-QGL-------------------- 248

  Fly   521 VDTWEFTQSLEVLDLSNNAINEFKPQHLDCLHRLKTLNLAHNRLQYLQENTFDCVKNLEELNLRR 585
              ||.:: :|:.||||.|.|                        |.|:..||.|:.||::|||..
 Frog   249 --TWTWS-ALQNLDLSGNDI------------------------QNLEPGTFQCLPNLQKLNLDS 286

  Fly   586 NRLSWIIEDQSAAAPFKGLRKLRRLDLHGNNLKQISTKAMSGLNNLEILNLGSNALASIQVNAFE 650
            |:|:                          |:.|.:..|...|.::           ::..|.:|
 Frog   287 NKLT--------------------------NVTQETLNAWISLTSI-----------TLSGNIWE 314

  Fly   651 HMLRLNKLVFKSLNFICDCDLVWFQQWLKNRFPQQAEHAVCGYPEHLLDRHLKSLSSSELVCVDS 715
            ...::..|||                ||||....:....:|..|:::....:.....:..:|.::
 Frog   315 CTKKICPLVF----------------WLKNFKGNKESIMICASPKNMQGEKVTDAVETYNICNET 363

  Fly   716 P-------KPRVEQEPDDMLAVNAANITLECIASSPTAASLAAA 752
            |       .|..:..|............||.::|:|..:|.:.|
 Frog   364 PVLATERAYPTTKPPPKPQFTPKPTIYKLESVSSTPYTSSPSPA 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbk	NP_611091.2	LRR	<293..642	CDD:443914	83/352 (24%)
		leucine-rich repeat	293..316	CDD:275380	1/22 (5%)
		leucine-rich repeat	317..338	CDD:275380	6/23 (26%)
		leucine-rich repeat	339..362	CDD:275380	5/22 (23%)
		leucine-rich repeat	363..386	CDD:275380	7/22 (32%)
		leucine-rich repeat	387..410	CDD:275380	7/22 (32%)
		leucine-rich repeat	411..434	CDD:275380	10/22 (45%)
		leucine-rich repeat	435..457	CDD:275380	8/22 (36%)
		leucine-rich repeat	458..481	CDD:275380	5/22 (23%)
		leucine-rich repeat	482..505	CDD:275380	8/22 (36%)
		leucine-rich repeat	506..529	CDD:275380	2/22 (9%)
		leucine-rich repeat	530..553	CDD:275380	7/22 (32%)
		leucine-rich repeat	554..577	CDD:275380	5/22 (23%)
		leucine-rich repeat	578..604	CDD:275380	6/25 (24%)
		leucine-rich repeat	607..630	CDD:275380	4/22 (18%)
		leucine-rich repeat	631..652	CDD:275380	2/20 (10%)
		LRRCT	665..712	CDD:214507	6/46 (13%)
		Ig_3	717..816	CDD:464046	8/36 (22%)
		Ig	835..924	CDD:472250
		Ig strand B	851..855	CDD:409353
		Ig strand C	864..868	CDD:409353
		Ig strand E	890..894	CDD:409353
		Ig strand F	904..909	CDD:409353
		Ig strand G	917..920	CDD:409353
		Ig_3	927..1013	CDD:464046
lrrtm4	XP_031755133.1	leucine-rich repeat	43..61	CDD:275380	3/41 (7%)
		leucine-rich repeat	64..86	CDD:275380	6/21 (29%)
		LRR	<81..>312	CDD:443914	79/315 (25%)
		leucine-rich repeat	87..110	CDD:275380	5/22 (23%)
		leucine-rich repeat	111..134	CDD:275380	7/22 (32%)
		leucine-rich repeat	135..158	CDD:275380	7/22 (32%)
		leucine-rich repeat	159..182	CDD:275380	10/22 (45%)
		leucine-rich repeat	183..206	CDD:275380	8/22 (36%)
		leucine-rich repeat	207..230	CDD:275380	5/22 (23%)
		leucine-rich repeat	231..254	CDD:275380	10/46 (22%)
		leucine-rich repeat	255..278	CDD:275380	12/46 (26%)
		leucine-rich repeat	279..297	CDD:275380	8/43 (19%)
		leucine-rich repeat	303..315	CDD:275378	2/22 (9%)