Protein Alignment CysRS and cysS

DIOPT Version :10

• Sequence 1: NP_611087.1
• Gene: CysRS / 36784
• FlyBaseID: FBgn0027091
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_415059.1
• Gene: cysS / 946969
• ECOCYCID: EG10196
• Length: 461
• Species: Escherichia coli
• Alignment Length: 620
• Identity: 185/620 - (29%)
• Similarity: 269/620 - (43%)
• Gaps: 182/620 - (29%)

  Fly    20 LKLFNSLTRQKEDFVPLDGNNVTWYSCGPTVYDASHMGHARSYISFDILRRILSDYFGYNIHYVM 84
            ||:||:||||||:|.|:....|..|.||.||||..|:||.|::::||::.|.|. :.||.:.||.
E. coli     2 LKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLR-FLGYKLKYVR 65

  Fly    85 NITDIDDKIIRRARQNHLFDEYAAEAQKLPLDELLGQQKEVLQRFQDTCAKNTDPDKKIMLDKTL 149
            ||||||||||:||.:|.  :.:.|                                   |:|:.:
E. coli    66 NITDIDDKIIKRANENG--ESFVA-----------------------------------MVDRMI 93

  Fly   150 QRMNDAVEALTKAVGKGDEREISEKRLLYLNEAKDPISDWLDSLKGAQINDNAVFEALPRYWEDQ 214
            ..|
E. coli    94 AEM-------------------------------------------------------------- 96

  Fly   215 FHNDMKSLNILPPDVLTRVSEYVPQIVTFIQKIIDNGLAYAANN-SVYFDVNGFDKREKHHYAKL 278
             |.|..:||||.||:..|.:.::.:|:...:::|..|.||.|:| .|.|||.
E. coli    97 -HKDFDALNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVADNGDVMFDVP------------- 147

  Fly   279 VPEAYG-----DTKSLQEGEGDLSIAEDRLSEKRSANDFALWKASKAGEPWWDSPWGKGRPGWHI 338
            ....||     |...||.|     ...|.:.:||:..||.|||.||.|||.|.||||.|||||||
E. coli   148 TDPTYGVLSRQDLDQLQAG-----ARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHI 207

  Fly   339 ECSAMASDIFGPTFDIHTGGVDLKFPHHDNELAQSEAAFNESEWVKYFLHTGHLTIAGCKMSKSL 403
            |||||.....|..||||.||.||.||||:||:|||..| ::.::|.|::|:|.:.:...||||||
E. coli   208 ECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCA-HDGQYVNYWMHSGMVMVDREKMSKSL 271

  Fly   404 KNFVTIQEALKKHSATQLRLAFLLHSWKDTLDYSENTMEMATQYEKFLNEFFLNVKDLTRHVLSE 468
            .||.|:::.||.:.|..:|...:...::..|:|||..::.|   ...|...:..::...:.|.
E. coli   272 GNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQA---RAALERLYTALRGTDKTVA-- 331

  Fly   469 EPRRQFDAWTEVEAALQKKFSNAQVQVHASLCDNIDTRSA----LDAIRELVSVSNVYIRDNKTR 529
                  .|..|   |.:.:|..|       :.|:.:|..|    .|..||:          |:.:
E. coli   332 ------PAGGE---AFEARFIEA-------MDDDFNTPEAYSVLFDMAREV----------NRLK 370

  Fly   530 LNSLLLRN-VATYITDLLHVFGAI-SGPRGGIGFPVSGGSGAQAAGADLETTVLPYVQSLAEFRY 592
            ...:...| :|:::..|..|.|.: ..|...:      .|||||..::           :||...
E. coli   371 AEDMAAANAMASHLRKLSAVLGLLEQEPEAFL------QSGAQADDSE-----------VAEIEA 418

  Fly   593 LVREQAKTLKAFDILKLCDDLRDNVLPNLGVRLED 627
            |::::....||.| ....|..||. |..:|:.|||
E. coli   419 LIQQRLDARKAKD-WAAADAARDR-LNEMGIVLED 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CysRS	NP_611087.1	PTZ00399	2..737	CDD:240402	185/620 (30%)
cysS	NP_415059.1	CysS	1..461	CDD:439985	185/620 (30%)