Protein Alignment CysRS and CysRS-m

DIOPT Version :10

• Sequence 1: NP_611087.1
• Gene: CysRS / 36784
• FlyBaseID: FBgn0027091
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: XP_001238361.3
• Gene: CysRS-m / 4577535
• VectorBaseID: AGAMI1_000174
• Length: 523
• Species: Anopheles gambiae
• Alignment Length: 630
• Identity: 186/630 - (29%)
• Similarity: 286/630 - (45%)
• Gaps: 153/630 - (24%)

  Fly    20 LKLFNSLTRQKEDFVPL----DGNNVTWYSCGPTVYDASHMGHARSYISFDILRRILSDYFGYNI 80
            |:|::...::|   |.|    ..:.:::|:|||||||::|:|||..|:..|||:|||..:|...:
Mosquito    18 LRLYDGRLKEK---VALQIHPSKSYLSFYTCGPTVYDSAHIGHASCYVRLDILQRILRHHFHLPL 79

  Fly    81 HYVMNITDIDDKIIRRARQNHLFDEYAAEAQKLPLDELLGQQKEVLQRFQDTCAKNTDPDKKIML 145
            ...|||||||||||.||.:..:
Mosquito    80 VTAMNITDIDDKIIARALEQQV------------------------------------------- 101

  Fly   146 DKTLQRMNDAVEALTKAVGKGDEREISEKRLLYLNEAKDPISDWLDSLKGAQINDNAVFEALPRY 210
                                                      ||               :.|...
Mosquito   102 ------------------------------------------DW---------------QQLASR 109

  Fly   211 WEDQFHNDMKSLNILPPDVLTRVSEYVPQIVTFIQKIIDNGLAYA-ANNSVYFDVNGFDKREKHH 274
            :||:|.:|::.||:..|||..||::::|.|:.|:|.:::.|.||: |:.||||:...:::
Mosquito   110 YEDEFWSDLQRLNVRAPDVKLRVTDHIPAIIRFVQTLVEKGFAYSTADGSVYFETAKYER----- 169

  Fly   275 YAKLVPEAYGDTKSLQEGEGDLSIAEDRLSEKRSANDFALWKASKAGEPWWDSP-WGKGRPGWHI 338
            |.||       .|.:.|.|.:.|     ..:||..:|||||||||.|||:|.:. :.:|||||||
Mosquito   170 YGKL-------QKVIIEPESNAS-----KGQKRHQSDFALWKASKPGEPFWTAQGFAQGRPGWHI 222

  Fly   339 ECSAMASDIFGPTFDIHTGGVDLKFPHHDNELAQSEAAFNESEWVKYFLHTGHLTIAG--CKMSK 401
            |||.:||.:||...|.|.||:||:||||:||..||....:..:||.::||||.|.:.|  .||||
Mosquito   223 ECSTLASHLFGRALDFHAGGLDLRFPHHENEETQSCCYHDVPDWVTHWLHTGQLHLEGQTHKMSK 287

  Fly   402 SLKNFVTIQEALKKHSATQLRLAFLLHSWKDTLDYSENTMEMATQYEKFLNEFFLNVKDLTRHVL 466
            ||||.|:|.|.|..:.|.:.|:..||..::..::|....|..|....:....||   .|....:.
Mosquito   288 SLKNTVSIGELLGAYGADEFRMLCLLSHYRSAIEYGPEAMGTARNVLRKFASFF---SDAKAFID 349

  Fly   467 SEEPRRQFDAWTEVEAALQKKFSNAQVQVHASLCDNIDTRSALDAIRELVSVSNVYIRDNKTRLN 531
            ..:| ..:|| |..|:.|: |.||.:..|...|.::.:|.:::.|:.||.|.....|..::...:
Mosquito   350 GLKP-ATYDA-TTTESLLE-KLSNTRTTVREFLKNDFNTANSVLALGELASNVQRIINSHEPSTS 411

  Fly   532 SLLLRN---------VATYITDLLHVFGAISGPRGGIGFPVSGGSGAQAAGADLETTVLPYVQSL 587
            .:.|..         |..||.:.|..:|..|       ........::..|.|...::...::::
Mosquito   412 GVSLIGSSNVGAVLAVTEYIREELVSYGVQS-------LDKQSPQHSRQMGNDANQSLEQLIEAM 469

  Fly   588 AEFRYLVREQAKTLKAFDILKLCDDLRDNVLPNLGVRLEDKDIGK 632
            ...|..:|.||...|...:.|:||.|||.:..   ..:|.||.||
Mosquito   470 VATRSEIRLQAIETKNPQLFKVCDLLRDRLKQ---ANVEVKDHGK 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CysRS	NP_611087.1	PTZ00399	2..737	CDD:240402	186/630 (30%)
CysRS-m	XP_001238361.3	None