DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Got1 and ASP1

DIOPT Version :9

Sequence 1:	NP_725534.1	Gene:	Got1 / 36782	FlyBaseID:	FBgn0001124	Length:	437	Species:	Drosophila melanogaster
Sequence 2:	NP_001118421.1	Gene:	ASP1 / 817648	AraportID:	AT2G30970	Length:	430	Species:	Arabidopsis thaliana

Alignment Length:	406	Identity:	185/406 - (45%)
Similarity:	249/406 - (61%)	Gaps:	3/406 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 STMSIYADVPKGPAIEVFALTQAFKDDSNPNKVNLSVGAYRTDAGVPWVLPVVRKTEISIASDEQ 84
            |..|.:..|...|...:..:|:||..|.:|.|||:.|||||.|.|.|.||..||:.|..:|....
plant    28 SMSSWWKSVEPAPKDPILGVTEAFLADPSPEKVNVGVGAYRDDNGKPVVLECVREAEKRLAGSTF 92

  Fly    85 VNHEYLPVTGLETFTNAATELVLGADSPAIKENRAFGVQTISGTGALRVAADFLHTQLNRNVVYY 149
            :  ||||:.|.....:...:|..|.:|..||:.|...|||:|||||.|:.|||.......:.:|.
plant    93 M--EYLPMGGSAKMVDLTLKLAYGDNSEFIKDKRIAAVQTLSGTGACRLFADFQKRFSPGSQIYI 155

  Fly   150 SNPTWENHHKIFCDAGFTTVKSYRYWDQNKRELDFKNMLADLNDAPPGAVIILHACAHNPTGIDP 214
            ..|||.|||.|:.||. ...|:|.|:....:.|||..::.|:.:||.|:..:||||||||||:||
plant   156 PVPTWSNHHNIWKDAQ-VPQKTYHYYHPETKGLDFSALMDDVKNAPEGSFFLLHACAHNPTGVDP 219

  Fly   215 TQEQWTELADLMEKKKLFPLFDSAYQGFASGDPDRDAWAARYFVQRGFELFICQSFAKNFGLYCE 279
            |:|||.|::.|.:.||.|..||.||||||||||.|||.:.|.|::.|..:.|.||:|||.|||.:
plant   220 TEEQWREISQLFKAKKHFAFFDMAYQGFASGDPARDAKSIRIFLEDGHHIGISQSYAKNMGLYGQ 284

  Fly   280 RTGNLAVVQKNGATKAAVHSQLTLLIRGQYSNPPAYGARIVSKVLNTPELRKEWMASIQAMSSRI 344
            |.|.|:|:.::.....||.|||..|.|..|||||.:||::||.:|..|||:..|:..::.|:.||
plant   285 RVGCLSVLCEDPKQAVAVKSQLQQLARPMYSNPPLHGAQLVSTILEDPELKSLWLKEVKVMADRI 349

  Fly   345 REMRTALRDKLVALGTPGTWDHIVNQIGMFSYTGLNESHVRVLIDQYHIYLLKTGRISMSGLNKG 409
            ..|||.||:.|..||:|.:|:|:..|||||.|:||....|..|..:||||:.:.|||||:|:..|
plant   350 IGMRTTLRESLEKLGSPLSWEHVTKQIGMFCYSGLTPEQVDRLTSEYHIYMTRNGRISMAGVTTG 414

  Fly   410 NVEYVAKAIHAAVTGS 425
            ||.|:|.|||.....|
plant   415 NVGYLANAIHEVTKSS 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Got1	NP_725534.1	PTZ00376	21..423	CDD:240390	183/401 (46%)
Got1	NP_725534.1	Aminotran_1_2	49..418	CDD:278580	173/368 (47%)
ASP1	NP_001118421.1	PLN02397	10..429	CDD:215222	184/403 (46%)
ASP1	NP_001118421.1	Aminotran_1_2	57..423	CDD:278580	173/368 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1448
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62835
OrthoDB	1	1.010	-	-		D1104596at2759
OrthoFinder	1	1.000	-	-		FOG0000707
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100337
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X428
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.730