DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Got1 and SPAC10F6.13c

DIOPT Version :9

Sequence 1:	NP_725534.1	Gene:	Got1 / 36782	FlyBaseID:	FBgn0001124	Length:	437	Species:	Drosophila melanogaster
Sequence 2:	NP_593264.1	Gene:	SPAC10F6.13c / 2543020	PomBaseID:	SPAC10F6.13c	Length:	409	Species:	Schizosaccharomyces pombe

Alignment Length:	401	Identity:	196/401 - (48%)
Similarity:	264/401 - (65%)	Gaps:	4/401 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 YADVPKGPAIEVFALTQAFKDDSNPNKVNLSVGAYRTDAGVPWVLPVVRKTEISIASDEQVNHEY 89
            :|::.:..|..:|.|...:..|.:|.|||:||||||.|.|.||:||.|:|....:......||||
pombe     6 FANIEEAKADAIFKLNAQYHQDEDPKKVNMSVGAYRDDTGKPWILPAVKKASKIVEEQASFNHEY 70

  Fly    90 LPVTGLETFTNAATELVLGADSPAIKENRAFGVQTISGTGALRVAADFLHTQLNRNV---VYYSN 151
            ||:.||..||.||.|::...:...:.|:|...:|::|||||..:||.|:.|...::.   ||.||
pombe    71 LPIAGLPRFTKAAAEVLFRPNPHLLSEDRVASMQSVSGTGANFLAASFIETFYVKHTGAHVYISN 135

  Fly   152 PTWENHHKIFCDAGFTTVKSYRYWDQNKRELDFKNMLADLNDAPPGAVIILHACAHNPTGIDPTQ 216
            |||..|..::...| .||.:|.|||...|..|::.||:.:..||.|::.:||||||||||||||:
pombe   136 PTWPVHRTLWEKLG-VTVDTYPYWDAKNRSFDYEGMLSTIKSAPEGSIFLLHACAHNPTGIDPTR 199

  Fly   217 EQWTELADLMEKKKLFPLFDSAYQGFASGDPDRDAWAARYFVQRGFELFICQSFAKNFGLYCERT 281
            |||..:.:.:..:|...:||.|||||||||.:||:||...||:...:.|:|||||||.|||.|||
pombe   200 EQWLSIFESLLSRKHLVVFDIAYQGFASGDLNRDSWALNEFVKYNKDFFVCQSFAKNMGLYGERT 264

  Fly   282 GNLAVVQKNGATKAAVHSQLTLLIRGQYSNPPAYGARIVSKVLNTPELRKEWMASIQAMSSRIRE 346
            |.:..|.|:.:||..|.|||.::.|...||||||||||.:::||:|:|..||...::.|||||.|
pombe   265 GCMHYVAKDASTKNKVLSQLCIVQRNTISNPPAYGARIAAEILNSPQLFAEWEQDLKTMSSRIIE 329

  Fly   347 MRTALRDKLVALGTPGTWDHIVNQIGMFSYTGLNESHVRVLIDQYHIYLLKTGRISMSGLNKGNV 411
            ||..|||.||||.|||:||||..||||||:|||..:.|:...::||:|....|||||:|||..||
pombe   330 MRKRLRDSLVALKTPGSWDHITQQIGMFSFTGLTPAQVQFCQERYHLYFSANGRISMAGLNNSNV 394

  Fly   412 EYVAKAIHAAV 422
            |:||:|.:.||
pombe   395 EHVAQAFNHAV 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Got1	NP_725534.1	PTZ00376	21..423	CDD:240390	196/401 (49%)
Got1	NP_725534.1	Aminotran_1_2	49..418	CDD:278580	188/371 (51%)
SPAC10F6.13c	NP_593264.1	TyrB	5..405	CDD:224365	194/399 (49%)
SPAC10F6.13c	NP_593264.1	Aminotran_1_2	30..401	CDD:278580	188/371 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	382	1.000	Domainoid score	I128
eggNOG	1	0.900	-	-		E1_COG1448
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1571
Inparanoid	1	1.050	399	1.000	Inparanoid score	I383
OMA	1	1.010	-	-		QHG62835
OrthoFinder	1	1.000	-	-		FOG0000707
OrthoInspector	1	1.000	-	-		oto100864
orthoMCL	1	0.900	-	-		OOG6_100337
Panther	1	1.100	-	-	LDO	PTHR11879
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2019
SonicParanoid	1	1.000	-	-		X428
TreeFam	1	0.960	-	-
	14	13.860