Protein Alignment Jhe and Ces1h

DIOPT Version :9

• Sequence 1: NP_001163166.1
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001357759.1
• Gene: Ces1h / 75704
• MGIID: 1922954
• Length: 562
• Species: Mus musculus
• Alignment Length: 599
• Identity: 168/599 - (28%)
• Similarity: 266/599 - (44%)
• Gaps: 123/599 - (20%)

  Fly    36 PPSVGCLKG------TNLQGYQSERFEAFMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMD 94
            ||.|....|      .:|:|: ::....|:|:|:|.||:|.|||:.|:.......:.:|::....
Mouse    23 PPVVNTTHGKVLGKYISLEGF-TQPVAVFLGVPFAKPPLGSLRFAPPQPPEPWSFVKNATSYPPM 86

  Fly    95 CIQKNYL--LPTPVVYGD---------EDCLYLNVYRP-EIRKSA--LPVMVYIHGGGFF--GGS 143
            |.|...|  :...::..:         |||||||||.| ::.|:.  |||||:|||||..  |.|
Mouse    87 CSQDAVLGQMVNDLIINNKEKIRLRFSEDCLYLNVYTPVDLMKNTNRLPVMVWIHGGGLVVGGAS 151

  Fly   144 AGPGVTGPEYFMDSGE-VILVTMAYRLGPFGFLSTQDAVMSGNFGLKDQNLALRWVQRNIRFFGG 207
            |..|.|     :.:.| |::||:.|||..:||.||.|....||:|..||..||.|:|.||..|||
Mouse   152 AYDGRT-----LSAHENVVVVTIQYRLAIWGFFSTGDEHSRGNWGHLDQLAALHWIQDNIANFGG 211

  Fly   208 DPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMSG---TANVPFAIAEQPLEQARLLAEFAD 269
            ||..||||||||||.:..:.:|||.:..||||.||.||   |:.:....|....||..:.|
Mouse   212 DPGSVTIFGQSAGGESVSVLVLSPLAKNLFHRAISQSGVVFTSGLFMEDASSVTEQIAVTA---- 272

  Fly   270 VPDARNLSTVKLTKALRRINATKLLNAGDGLKYWDVDHMTN------FRPVVEEGLEVDAFLNAH 328
              ..:..::..:...||:....:||.....:..:.:|...|      |.|.|.:|:    .|...
Mouse   273 --GCKTTTSAVIVHCLRQKTEEELLEIMQKMNLFKLDAQENTKKNYPFLPTVLDGV----VLPKA 331

  Fly   329 PMDMLAQGMPTSIPLLLGTVPGEGAVRVVNILGNETLRQSFNLRFDELLQELLEF-PASFSQDRR 392
            |..:||:....::|.::|          :|       :|.|..    .|..::|| |.....|::
Mouse   332 PEAILAEKNFNTVPYIVG----------IN-------KQEFGW----TLPMIMEFPPTDVKLDKK 375

  Fly   393 ----------------EKMMDLLVEVYFQGQHEVNELTVQGFMNLISDRGFKQP--LYNTIHKNV 439
                            |..:.:.:|.|.:|..:..:..| ..:.||.|..|..|  :.:..|::
Mouse   376 VISLFLRKLAYFFNIPEDGIPVAIEKYSKGTDDPIQNRV-WLLQLIGDVMFGIPSVIVSRGHRD- 438

  Fly   440 CHTPNPVYLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDLLYLFRSPLLFPDFQRNSTEAKVIH 504
              ...|.|:|.|  |...|::|......|||.:|    |::..:|.:|:|    :..|:|.::..
Mouse   439 --AGAPTYMYEF--QSRPSFSSELKPKTVTGDHG----DEVYSVFGAPIL----REGSSEEEINL 491

  Fly   505 S--FVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGICDYHEFANAPDAYQ--GFEVHVASEFQ 565
            |  .:.::.:||:.|.|..                .|:..:.|: |....|.  |.....|...:
Mouse   492 SKMMMKFWANFARNGNPNG----------------QGLPHWPEY-NQKKGYLQIGATTQQAQGLK 539

  Fly   566 TDRVNLWSHILNEK 579
            ...|:||:.:..:|
Mouse   540 DKEVSLWTELRAKK 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_001163166.1	COesterase	40..527	CDD:278561	155/539 (29%)
Ces1h	NP_001357759.1	COesterase	24..546	CDD:365897	164/589 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832549
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.840